Patients with Klinefelter syndrome appear to be predisposed to the development of extragonadal cerebral germinomas. A case of a pineal region germinoma in a boy 15 years of age with Klinefelter syndrome is documented in this article. In view of three other cases of cerebral germinomas associated with Klinefelter syndrome in the literature, a hypothesis for this predisposition is suggested.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Mar 15 1988|
ASJC Scopus subject areas
- Cancer Research