Cerebral dysfunction after coronary artery bypass grafting done with mild or moderate hypothermia

E. J. Heyer, David C. Adams, Ellise S. Delphin, D. J. McMahon, S. D. Steneck, M. C. Oz, Robert E. Michler, E. A. Rose

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objective: Ninety-nine patients undergoing elective coronary artery bypass grafting were enrolled in a prospective, randomized study to evaluate the incidence of cerebral dysfunction after 'mild' or 'moderate' hypothermia during cardiopulmonary bypass. Methods: Patients were evaluated before and after operation before hospital discharge and in some cases at follow-up at least 6 weeks later with a complete neurologic examination (85 patients) and a battery of standard neuropsychometric tests (86 patients). Results: Postoperative changes detected by neurologic examination consisted of the appearance of new primitive reflexes in both groups. No statistically significant differences in incidence were found. The neuropsychometric performances of the two groups were statistically similar by either event- rate or group-rate analysis. Conclusions: There is no detectable difference in postoperative cerebral dysfunction in patients undergoing coronary artery bypass grafting who are supported by cardiopulmonary bypass with either mild or moderate hypothermia.

Original languageEnglish (US)
Pages (from-to)270-277
Number of pages8
JournalJournal of Thoracic and Cardiovascular Surgery
Volume114
Issue number2
DOIs
StatePublished - 1997
Externally publishedYes

Fingerprint

Hypothermia
Coronary Artery Bypass
Neurologic Examination
Cardiopulmonary Bypass
Incidence
Reflex
Prospective Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Cerebral dysfunction after coronary artery bypass grafting done with mild or moderate hypothermia. / Heyer, E. J.; Adams, David C.; Delphin, Ellise S.; McMahon, D. J.; Steneck, S. D.; Oz, M. C.; Michler, Robert E.; Rose, E. A.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 114, No. 2, 1997, p. 270-277.

Research output: Contribution to journalArticle

@article{502077b41b9842a89fc068ab4e516b83,
title = "Cerebral dysfunction after coronary artery bypass grafting done with mild or moderate hypothermia",
abstract = "Objective: Ninety-nine patients undergoing elective coronary artery bypass grafting were enrolled in a prospective, randomized study to evaluate the incidence of cerebral dysfunction after 'mild' or 'moderate' hypothermia during cardiopulmonary bypass. Methods: Patients were evaluated before and after operation before hospital discharge and in some cases at follow-up at least 6 weeks later with a complete neurologic examination (85 patients) and a battery of standard neuropsychometric tests (86 patients). Results: Postoperative changes detected by neurologic examination consisted of the appearance of new primitive reflexes in both groups. No statistically significant differences in incidence were found. The neuropsychometric performances of the two groups were statistically similar by either event- rate or group-rate analysis. Conclusions: There is no detectable difference in postoperative cerebral dysfunction in patients undergoing coronary artery bypass grafting who are supported by cardiopulmonary bypass with either mild or moderate hypothermia.",
author = "Heyer, {E. J.} and Adams, {David C.} and Delphin, {Ellise S.} and McMahon, {D. J.} and Steneck, {S. D.} and Oz, {M. C.} and Michler, {Robert E.} and Rose, {E. A.}",
year = "1997",
doi = "10.1016/S0022-5223(97)70155-7",
language = "English (US)",
volume = "114",
pages = "270--277",
journal = "Journal of Thoracic and Cardiovascular Surgery",
issn = "0022-5223",
publisher = "Mosby Inc.",
number = "2",

}

TY - JOUR

T1 - Cerebral dysfunction after coronary artery bypass grafting done with mild or moderate hypothermia

AU - Heyer, E. J.

AU - Adams, David C.

AU - Delphin, Ellise S.

AU - McMahon, D. J.

AU - Steneck, S. D.

AU - Oz, M. C.

AU - Michler, Robert E.

AU - Rose, E. A.

PY - 1997

Y1 - 1997

N2 - Objective: Ninety-nine patients undergoing elective coronary artery bypass grafting were enrolled in a prospective, randomized study to evaluate the incidence of cerebral dysfunction after 'mild' or 'moderate' hypothermia during cardiopulmonary bypass. Methods: Patients were evaluated before and after operation before hospital discharge and in some cases at follow-up at least 6 weeks later with a complete neurologic examination (85 patients) and a battery of standard neuropsychometric tests (86 patients). Results: Postoperative changes detected by neurologic examination consisted of the appearance of new primitive reflexes in both groups. No statistically significant differences in incidence were found. The neuropsychometric performances of the two groups were statistically similar by either event- rate or group-rate analysis. Conclusions: There is no detectable difference in postoperative cerebral dysfunction in patients undergoing coronary artery bypass grafting who are supported by cardiopulmonary bypass with either mild or moderate hypothermia.

AB - Objective: Ninety-nine patients undergoing elective coronary artery bypass grafting were enrolled in a prospective, randomized study to evaluate the incidence of cerebral dysfunction after 'mild' or 'moderate' hypothermia during cardiopulmonary bypass. Methods: Patients were evaluated before and after operation before hospital discharge and in some cases at follow-up at least 6 weeks later with a complete neurologic examination (85 patients) and a battery of standard neuropsychometric tests (86 patients). Results: Postoperative changes detected by neurologic examination consisted of the appearance of new primitive reflexes in both groups. No statistically significant differences in incidence were found. The neuropsychometric performances of the two groups were statistically similar by either event- rate or group-rate analysis. Conclusions: There is no detectable difference in postoperative cerebral dysfunction in patients undergoing coronary artery bypass grafting who are supported by cardiopulmonary bypass with either mild or moderate hypothermia.

UR - http://www.scopus.com/inward/record.url?scp=0030793058&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030793058&partnerID=8YFLogxK

U2 - 10.1016/S0022-5223(97)70155-7

DO - 10.1016/S0022-5223(97)70155-7

M3 - Article

C2 - 9270646

AN - SCOPUS:0030793058

VL - 114

SP - 270

EP - 277

JO - Journal of Thoracic and Cardiovascular Surgery

JF - Journal of Thoracic and Cardiovascular Surgery

SN - 0022-5223

IS - 2

ER -