Cerebellar alterations in the weaver mouse

Asao Hirano, Herbert M. Dembitzerc

Research output: Contribution to journalArticle

133 Scopus citations

Abstract

The fine structure of the cerebellum of weaver mouse was examined and the paucity of granule cells and their axons, the parallel fibers, was confirmed. Unexpectedly, however, the dendritic spines of the Purkinje cells which, in normal animals, are the postsynaptic mates of the parallel fibers, were present. Furthermore, their essential morphology and their staining reactions were indistinguishable from those of the Purkinie cell dendritic spines in normal animals. Possible mechanisms of development are discussed.

Original languageEnglish (US)
Pages (from-to)478-486
Number of pages9
JournalJournal of Cell Biology
Volume56
Issue number2
DOIs
StatePublished - Feb 1 1973

ASJC Scopus subject areas

  • Cell Biology

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