Cellular transport and homeostasis of essential and nonessential metals

Ebany J. Martinez-Finley; Sudipta Chakraborty; Stephanie J.B. Fretham; Michael Aschner

doi:10.1039/c2mt00185c

Cellular transport and homeostasis of essential and nonessential metals

Ebany J. Martinez-Finley, Sudipta Chakraborty, Stephanie J.B. Fretham, Michael Aschner

Research output: Contribution to journal › Article › peer-review

164 Scopus citations

Abstract

Metals can have a number of detrimental or beneficial effects in the cell, but first they must get in. Organisms have evolved transport mechanisms to get metals that are required, or essential into the cell. Nonessential metals often enter the cell through use of the machinery provided for essential metals. Much work has been done to advance our understanding of how these metals are transported across plasma and organelle membranes. This review provides an overview of essential and nonessential metal transport and homeostatic processes.

Original language	English (US)
Pages (from-to)	593-605
Number of pages	13
Journal	Metallomics
Volume	4
Issue number	7
DOIs	https://doi.org/10.1039/c2mt00185c
State	Published - Jul 2012
Externally published	Yes

ASJC Scopus subject areas

Chemistry (miscellaneous)
Biophysics
Biomaterials
Biochemistry
Metals and Alloys

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10.1039/c2mt00185c

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Cellular transport and homeostasis of essential and nonessential metals

Abstract

ASJC Scopus subject areas

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