CDK6, a new target in MLL-driven leukemia

Iléana Antony-Debré, Ulrich Steidl

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

In this issue of Blood, Placke et al identify the cell-cycle regulator CDK6 as a promising new target in mixed lineage leukemia (MLL)-rearranged acute myeloid leukemia (AML) and show that its downregulation or pharmacological inhibition leads to growth inhibition and differentiation of MLL-driven leukemic cells.

Original languageEnglish (US)
Pages (from-to)5-6
Number of pages2
JournalBlood
Volume124
Issue number1
DOIs
StatePublished - Jul 3 2014

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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