Case report: Baylisascaris procyonis and herpes simplex virus 2 coinfection presenting as ocular larva migrans with granuloma formation in a child

Grace Liu, Glenn Fennelly, Kevin R. Kazacos, Charles Grose, Joanna Dobroszycki, Norman Saffra, Christina M. Coyle, Louis M. Weiss, Moshe M. Szlechter, Herbert B. Tanowitz

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Ocular Baylisascaris procyonis infection results from ingestion of infective eggs of B. procyonis, the raccoon ascarid. Herpes simplex virus type 2 (HSV-2) infection of the retina is the result of either primary infection or reactivated disease. Herein, we report a case of a 12-year-old female resident of the Bronx in New York City, who presented with pan-uveitis and vision loss. Initial evaluation for etiologic causes was nondiagnostic. Serology for anti-Baylisascaris procyonis antibodies in serum and vitreous fluid were both positive. Polymerase chain reaction (PCR) of vitreous fluid was positive for HSV-2. Treatment with vitrectomy, albendazole, and acyclovir resulted in mild improvement of visual acuity. The atypical presentation of B. procyonis in this case, as ocular larva migrans with a peripheral granuloma and retinal detachment, underscores the importance of maintaining a high degree of suspicion for this pathogen even in non-diffuse unilateral subacute neuroretinitis (DUSN) patients in urban areas. This case further illustrates that it is possible to have coexisting infections in cases of posterior uveitis.

Original languageEnglish (US)
Pages (from-to)612-614
Number of pages3
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number3
StatePublished - Sep 1 2015


ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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