Abstract
Ocular Baylisascaris procyonis infection results from ingestion of infective eggs of B. procyonis, the raccoon ascarid. Herpes simplex virus type 2 (HSV-2) infection of the retina is the result of either primary infection or reactivated disease. Herein, we report a case of a 12-year-old female resident of the Bronx in New York City, who presented with pan-uveitis and vision loss. Initial evaluation for etiologic causes was nondiagnostic. Serology for anti-Baylisascaris procyonis antibodies in serum and vitreous fluid were both positive. Polymerase chain reaction (PCR) of vitreous fluid was positive for HSV-2. Treatment with vitrectomy, albendazole, and acyclovir resulted in mild improvement of visual acuity. The atypical presentation of B. procyonis in this case, as ocular larva migrans with a peripheral granuloma and retinal detachment, underscores the importance of maintaining a high degree of suspicion for this pathogen even in non-diffuse unilateral subacute neuroretinitis (DUSN) patients in urban areas. This case further illustrates that it is possible to have coexisting infections in cases of posterior uveitis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 612-614 |
| Number of pages | 3 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 93 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1 2015 |
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ASJC Scopus subject areas
- Parasitology
- Infectious Diseases
- Virology
Cite this
Case report : Baylisascaris procyonis and herpes simplex virus 2 coinfection presenting as ocular larva migrans with granuloma formation in a child. / Liu, Grace; Fennelly, Glenn; Kazacos, Kevin R.; Grose, Charles; Dobroszycki, Joanna; Saffra, Norman; Coyle, Christina M.; Weiss, Louis M.; Szlechter, Moshe M.; Tanowitz, Herbert B.
In: American Journal of Tropical Medicine and Hygiene, Vol. 93, No. 3, 01.09.2015, p. 612-614.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Case report
T2 - Baylisascaris procyonis and herpes simplex virus 2 coinfection presenting as ocular larva migrans with granuloma formation in a child
AU - Liu, Grace
AU - Fennelly, Glenn
AU - Kazacos, Kevin R.
AU - Grose, Charles
AU - Dobroszycki, Joanna
AU - Saffra, Norman
AU - Coyle, Christina M.
AU - Weiss, Louis M.
AU - Szlechter, Moshe M.
AU - Tanowitz, Herbert B.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Ocular Baylisascaris procyonis infection results from ingestion of infective eggs of B. procyonis, the raccoon ascarid. Herpes simplex virus type 2 (HSV-2) infection of the retina is the result of either primary infection or reactivated disease. Herein, we report a case of a 12-year-old female resident of the Bronx in New York City, who presented with pan-uveitis and vision loss. Initial evaluation for etiologic causes was nondiagnostic. Serology for anti-Baylisascaris procyonis antibodies in serum and vitreous fluid were both positive. Polymerase chain reaction (PCR) of vitreous fluid was positive for HSV-2. Treatment with vitrectomy, albendazole, and acyclovir resulted in mild improvement of visual acuity. The atypical presentation of B. procyonis in this case, as ocular larva migrans with a peripheral granuloma and retinal detachment, underscores the importance of maintaining a high degree of suspicion for this pathogen even in non-diffuse unilateral subacute neuroretinitis (DUSN) patients in urban areas. This case further illustrates that it is possible to have coexisting infections in cases of posterior uveitis.
AB - Ocular Baylisascaris procyonis infection results from ingestion of infective eggs of B. procyonis, the raccoon ascarid. Herpes simplex virus type 2 (HSV-2) infection of the retina is the result of either primary infection or reactivated disease. Herein, we report a case of a 12-year-old female resident of the Bronx in New York City, who presented with pan-uveitis and vision loss. Initial evaluation for etiologic causes was nondiagnostic. Serology for anti-Baylisascaris procyonis antibodies in serum and vitreous fluid were both positive. Polymerase chain reaction (PCR) of vitreous fluid was positive for HSV-2. Treatment with vitrectomy, albendazole, and acyclovir resulted in mild improvement of visual acuity. The atypical presentation of B. procyonis in this case, as ocular larva migrans with a peripheral granuloma and retinal detachment, underscores the importance of maintaining a high degree of suspicion for this pathogen even in non-diffuse unilateral subacute neuroretinitis (DUSN) patients in urban areas. This case further illustrates that it is possible to have coexisting infections in cases of posterior uveitis.
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U2 - 10.4269/ajtmh.15-0272
DO - 10.4269/ajtmh.15-0272
M3 - Article
VL - 93
SP - 612
EP - 614
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 3
ER -