Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin.

Y. Yiting, Iti Chaturvedi, Liew Kim Meow, Pandjassarame Kangueane, Meena Kishore Sakharkar

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Gene fusion has been described as an important evolutionary phenomenon. This report focuses on identifying, analyzing, and tabulating human fusion proteins of prokaryotic origin. These fusion proteins are found to mimic operons, simulate protein-protein interfaces in prokaryotes, exhibiting multiple functions and alternative splicing in humans. The accredited biological functions for each of these proteins is made available as a database at http://sege.ntu.edu.sg/wester/fusion/

Original languageEnglish (US)
Pages (from-to)2964-2971
Number of pages8
JournalFrontiers in Bioscience
Volume9
StatePublished - 2004
Externally publishedYes

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Gene Fusion
Fusion reactions
Genes
Proteins
Alternative Splicing
Operon
Databases

Cite this

Yiting, Y., Chaturvedi, I., Meow, L. K., Kangueane, P., & Sakharkar, M. K. (2004). Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin. Frontiers in Bioscience, 9, 2964-2971.

Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin. / Yiting, Y.; Chaturvedi, Iti; Meow, Liew Kim; Kangueane, Pandjassarame; Sakharkar, Meena Kishore.

In: Frontiers in Bioscience, Vol. 9, 2004, p. 2964-2971.

Research output: Contribution to journalArticle

Yiting, Y, Chaturvedi, I, Meow, LK, Kangueane, P & Sakharkar, MK 2004, 'Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin.', Frontiers in Bioscience, vol. 9, pp. 2964-2971.
Yiting Y, Chaturvedi I, Meow LK, Kangueane P, Sakharkar MK. Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin. Frontiers in Bioscience. 2004;9:2964-2971.
Yiting, Y. ; Chaturvedi, Iti ; Meow, Liew Kim ; Kangueane, Pandjassarame ; Sakharkar, Meena Kishore. / Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin. In: Frontiers in Bioscience. 2004 ; Vol. 9. pp. 2964-2971.
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