Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin.

Y. Yiting; Iti Chaturvedi; Liew Kim Meow; Pandjassarame Kangueane; Meena Kishore Sakharkar

doi:10.2741/1451

Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin.

Y. Yiting, Iti Chaturvedi, Liew Kim Meow, Pandjassarame Kangueane, Meena Kishore Sakharkar

Epidemiology & Population Health

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Gene fusion has been described as an important evolutionary phenomenon. This report focuses on identifying, analyzing, and tabulating human fusion proteins of prokaryotic origin. These fusion proteins are found to mimic operons, simulate protein-protein interfaces in prokaryotes, exhibiting multiple functions and alternative splicing in humans. The accredited biological functions for each of these proteins is made available as a database at http://sege.ntu.edu.sg/wester/fusion/

Original language	English (US)
Pages (from-to)	2964-2971
Number of pages	8
Journal	Frontiers in bioscience : a journal and virtual library
Volume	9
DOIs	https://doi.org/10.2741/1451
State	Published - Sep 1 2004

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)

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