Abstract
Gene fusion has been described as an important evolutionary phenomenon. This report focuses on identifying, analyzing, and tabulating human fusion proteins of prokaryotic origin. These fusion proteins are found to mimic operons, simulate protein-protein interfaces in prokaryotes, exhibiting multiple functions and alternative splicing in humans. The accredited biological functions for each of these proteins is made available as a database at http://sege.ntu.edu.sg/wester/fusion/
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2964-2971 |
| Number of pages | 8 |
| Journal | Frontiers in bioscience : a journal and virtual library |
| Volume | 9 |
| DOIs | |
| State | Published - Sep 1 2004 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)
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Cite this
Yiting, Y., Chaturvedi, I., Meow, L. K., Kangueane, P., & Sakharkar, M. K. (2004). Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin. Frontiers in bioscience : a journal and virtual library, 9, 2964-2971. https://doi.org/10.2741/1451