Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin.

Y. Yiting, Iti Chaturvedi, Liew Kim Meow, Pandjassarame Kangueane, Meena Kishore Sakharkar

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Gene fusion has been described as an important evolutionary phenomenon. This report focuses on identifying, analyzing, and tabulating human fusion proteins of prokaryotic origin. These fusion proteins are found to mimic operons, simulate protein-protein interfaces in prokaryotes, exhibiting multiple functions and alternative splicing in humans. The accredited biological functions for each of these proteins is made available as a database at http://sege.ntu.edu.sg/wester/fusion/

Original languageEnglish (US)
Pages (from-to)2964-2971
Number of pages8
JournalFrontiers in bioscience : a journal and virtual library
Volume9
DOIs
Publication statusPublished - Sep 1 2004

    Fingerprint

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this