Blood transfusion and lung cancer recurrence

Steven M. Keller, Nael Martini, Larry R. Kaiser, Susan Groshen

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

Recent reports have suggested that perioperative blood transfusions may adversely affect prognosis after resection of non‐small cell lung cancer (NSCLC). To determine the impact of perioperative transfusion on the recurrence‐free interval, the status of 352 patients who underwent pulmonary resection for pathologic Stages I and II NSCLC was investigated. Transfused patients were significantly older than untransfused patients (P = 0.0009) but were not significantly different in sex distribution (P = 0.12) or tumor stage (P = 0.09). Recurrence was not significantly different in transfused patients when compared with patients who received no blood (P = 0.23) even when stratified for stage (Stage I, P = 0.58; Stage II, P = 0.14). Furthermore, the number of units transfused was not associated with time to tumor recurrence (P = 0.58). Contrary to other reports, these results do not support the contention that perioperative blood transfusion is significantly associated with decreased recurrence‐free survival.

Original languageEnglish (US)
Pages (from-to)606-610
Number of pages5
JournalCancer
Volume62
Issue number3
DOIs
StatePublished - Aug 1 1988

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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