Blood transfusion and lung cancer recurrence

Steven M. Keller; Nael Martini; Larry R. Kaiser; Susan Groshen

doi:10.1002/1097-0142(19880801)62:3<606::AID-CNCR2820620327>3.0.CO;2-Q

Blood transfusion and lung cancer recurrence

Steven M. Keller, Nael Martini, Larry R. Kaiser, Susan Groshen

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

Recent reports have suggested that perioperative blood transfusions may adversely affect prognosis after resection of non‐small cell lung cancer (NSCLC). To determine the impact of perioperative transfusion on the recurrence‐free interval, the status of 352 patients who underwent pulmonary resection for pathologic Stages I and II NSCLC was investigated. Transfused patients were significantly older than untransfused patients (P = 0.0009) but were not significantly different in sex distribution (P = 0.12) or tumor stage (P = 0.09). Recurrence was not significantly different in transfused patients when compared with patients who received no blood (P = 0.23) even when stratified for stage (Stage I, P = 0.58; Stage II, P = 0.14). Furthermore, the number of units transfused was not associated with time to tumor recurrence (P = 0.58). Contrary to other reports, these results do not support the contention that perioperative blood transfusion is significantly associated with decreased recurrence‐free survival.

Original language	English (US)
Pages (from-to)	606-610
Number of pages	5
Journal	Cancer
Volume	62
Issue number	3
DOIs	https://doi.org/10.1002/1097-0142(19880801)62:3<606::AID-CNCR2820620327>3.0.CO;2-Q
State	Published - Aug 1 1988
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/1097-0142(19880801)62:3<606::AID-CNCR2820620327>3.0.CO;2-Q

Cite this

@article{defe7707cfcc445f8d6cd041f2966785,

title = "Blood transfusion and lung cancer recurrence",

abstract = "Recent reports have suggested that perioperative blood transfusions may adversely affect prognosis after resection of non‐small cell lung cancer (NSCLC). To determine the impact of perioperative transfusion on the recurrence‐free interval, the status of 352 patients who underwent pulmonary resection for pathologic Stages I and II NSCLC was investigated. Transfused patients were significantly older than untransfused patients (P = 0.0009) but were not significantly different in sex distribution (P = 0.12) or tumor stage (P = 0.09). Recurrence was not significantly different in transfused patients when compared with patients who received no blood (P = 0.23) even when stratified for stage (Stage I, P = 0.58; Stage II, P = 0.14). Furthermore, the number of units transfused was not associated with time to tumor recurrence (P = 0.58). Contrary to other reports, these results do not support the contention that perioperative blood transfusion is significantly associated with decreased recurrence‐free survival.",

author = "Keller, {Steven M.} and Nael Martini and Kaiser, {Larry R.} and Susan Groshen",

year = "1988",

month = aug,

day = "1",

doi = "10.1002/1097-0142(19880801)62:3<606::AID-CNCR2820620327>3.0.CO;2-Q",

language = "English (US)",

volume = "62",

pages = "606--610",

journal = "Cancer",

issn = "0008-543X",

publisher = "John Wiley and Sons Inc.",

number = "3",

}

TY - JOUR

T1 - Blood transfusion and lung cancer recurrence

AU - Keller, Steven M.

AU - Martini, Nael

AU - Kaiser, Larry R.

AU - Groshen, Susan

PY - 1988/8/1

Y1 - 1988/8/1

N2 - Recent reports have suggested that perioperative blood transfusions may adversely affect prognosis after resection of non‐small cell lung cancer (NSCLC). To determine the impact of perioperative transfusion on the recurrence‐free interval, the status of 352 patients who underwent pulmonary resection for pathologic Stages I and II NSCLC was investigated. Transfused patients were significantly older than untransfused patients (P = 0.0009) but were not significantly different in sex distribution (P = 0.12) or tumor stage (P = 0.09). Recurrence was not significantly different in transfused patients when compared with patients who received no blood (P = 0.23) even when stratified for stage (Stage I, P = 0.58; Stage II, P = 0.14). Furthermore, the number of units transfused was not associated with time to tumor recurrence (P = 0.58). Contrary to other reports, these results do not support the contention that perioperative blood transfusion is significantly associated with decreased recurrence‐free survival.

AB - Recent reports have suggested that perioperative blood transfusions may adversely affect prognosis after resection of non‐small cell lung cancer (NSCLC). To determine the impact of perioperative transfusion on the recurrence‐free interval, the status of 352 patients who underwent pulmonary resection for pathologic Stages I and II NSCLC was investigated. Transfused patients were significantly older than untransfused patients (P = 0.0009) but were not significantly different in sex distribution (P = 0.12) or tumor stage (P = 0.09). Recurrence was not significantly different in transfused patients when compared with patients who received no blood (P = 0.23) even when stratified for stage (Stage I, P = 0.58; Stage II, P = 0.14). Furthermore, the number of units transfused was not associated with time to tumor recurrence (P = 0.58). Contrary to other reports, these results do not support the contention that perioperative blood transfusion is significantly associated with decreased recurrence‐free survival.

UR - http://www.scopus.com/inward/record.url?scp=0023801988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023801988&partnerID=8YFLogxK

U2 - 10.1002/1097-0142(19880801)62:3<606::AID-CNCR2820620327>3.0.CO;2-Q

DO - 10.1002/1097-0142(19880801)62:3<606::AID-CNCR2820620327>3.0.CO;2-Q

M3 - Article

C2 - 3390797

AN - SCOPUS:0023801988

SN - 0008-543X

VL - 62

SP - 606

EP - 610

JO - Cancer

JF - Cancer

IS - 3

ER -

Blood transfusion and lung cancer recurrence

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this