Blood transfusion and lung cancer recurrence

S. M. Keller, S. Groshen, N. Martini, L. R. Kaiser

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Recent reports have suggested that perioperative blood transfusions may advrsely affect prognosis after resection of non-small cell lung cancer (NSCLC). To determine the impact of perioperative transfusion on the recurrence-free interval, the status of 352 patients who underwent pulmonary resection for pathologic Stages I and II NSCLC was investigated. Tranfused patients were significantly older than untransfused patients (P = 0.0009) but were not significantly different in sex distribution (P = 0.12) or tumor stage (P = 0.09). Recurrence was not significantly different in transfused patients when compared with patients who received no blood (P = 0.23) even when stratified for stage (Stage I, P = 0.58; Stage II, P = 0.14). Furthermore, the number of units transfused was not associated with time to tumor recurrence (P = 0.58). Contrary to other reports, these results do not support the contention that perioperative blood transfusion is significantly associated with decreased recurrence-free survival.

Original languageEnglish (US)
Pages (from-to)606-610
Number of pages5
JournalCancer
Volume62
Issue number3
StatePublished - 1988
Externally publishedYes

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Blood Transfusion
Lung Neoplasms
Recurrence
Non-Small Cell Lung Carcinoma
Sex Distribution
Neoplasms
Lung
Survival

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Keller, S. M., Groshen, S., Martini, N., & Kaiser, L. R. (1988). Blood transfusion and lung cancer recurrence. Cancer, 62(3), 606-610.

Blood transfusion and lung cancer recurrence. / Keller, S. M.; Groshen, S.; Martini, N.; Kaiser, L. R.

In: Cancer, Vol. 62, No. 3, 1988, p. 606-610.

Research output: Contribution to journalArticle

Keller, SM, Groshen, S, Martini, N & Kaiser, LR 1988, 'Blood transfusion and lung cancer recurrence', Cancer, vol. 62, no. 3, pp. 606-610.
Keller SM, Groshen S, Martini N, Kaiser LR. Blood transfusion and lung cancer recurrence. Cancer. 1988;62(3):606-610.
Keller, S. M. ; Groshen, S. ; Martini, N. ; Kaiser, L. R. / Blood transfusion and lung cancer recurrence. In: Cancer. 1988 ; Vol. 62, No. 3. pp. 606-610.
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