Biocompatible carbon nanotubes generated by functionalization with glycodendrimers

Peng Wu, Xing Chen, Nancy Hu, Un Chong Tam, Ola Blixt, Alex Zettl, Carolyn R. Bertozzi

Research output: Contribution to journalArticlepeer-review

171 Scopus citations

Abstract

Protective coatings: Glycodendrimers can function as homogeneous bioactive coatings that mitigate the cytotoxicity of single-walled carbon nanotubes (SWNTs). The bifunctional glycodendrimers (see picture) have peripheral carbohydrate units and a pyrene tail capable of binding SWNT surfaces through π-π interaction. Cells cultured with glycodendrimer-coated SWNTs proliferate at the same rate as untreated cells. (Chemical Equation Presented)

Original languageEnglish (US)
Pages (from-to)5022-5025
Number of pages4
JournalAngewandte Chemie - International Edition
Volume47
Issue number27
DOIs
StatePublished - Jun 23 2008
Externally publishedYes

Keywords

  • Biomimetic synthesis
  • Carbon
  • Dendrimers
  • Glycoconjugates
  • Nanotubes

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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