Behavior and social competency in idiopathic and cryptogenic childhood epilepsy

Anne T. Berg, Barbara G. Vickrey, Francine M. Testa, Susan R. Levy, Shlomo Shinnar, Francis Dimario

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Behavioral and related disorders are frequently reported in association with childhood epilepsy but the reasons for this are unclear. In a long-term prospective, community-based study of newly-diagnosed childhood epilepsy, behavioral assessments (Child Behavior Checklist) were performed in children 8 to 9 years after the initial diagnosis of epilepsy to determine the impact of remission and medication status on behavioral problems. Children with epilepsy were also compared with sibling controls. A total of 226 children (108 females, 118 males; mean age 13y 1mo [SD 2y 8mo], range 8-17y) with idiopathic or cryptogenic epilepsy were included in the analyses. One hundred and twenty-eight matched pairs were included in analyses of case-sibling differences. Lack of remission and current medication use were associated with worse behavioral problem and competency scores. Lack of remission generally had a greater effect than medication use, except for attention problems; medication status had the more deleterious effect (p<0.001). Children with epilepsy had significantly worse behavioral problems and competency scores relative to sibling controls. Even in paris in which the patient was seizure-free and off medication, significant case-sibling differences persisted for most scales (p=0.05 to p=0.001). Lack of remission and continued use of antiepileptic drugs have a negative influence on behavioral problems in children with epilepsy but do not fully explain the worse scores relative to siblings. This suggests an independent effect associated with the epilepsy itself.

Original languageEnglish (US)
Pages (from-to)487-492
Number of pages6
JournalDevelopmental Medicine and Child Neurology
Volume49
Issue number7
DOIs
StatePublished - Jul 2007

Fingerprint

Epilepsy
Siblings
Child Behavior
Paris
Checklist
Anticonvulsants
Seizures
Problem Behavior

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

Cite this

Behavior and social competency in idiopathic and cryptogenic childhood epilepsy. / Berg, Anne T.; Vickrey, Barbara G.; Testa, Francine M.; Levy, Susan R.; Shinnar, Shlomo; Dimario, Francis.

In: Developmental Medicine and Child Neurology, Vol. 49, No. 7, 07.2007, p. 487-492.

Research output: Contribution to journalArticle

Berg, Anne T. ; Vickrey, Barbara G. ; Testa, Francine M. ; Levy, Susan R. ; Shinnar, Shlomo ; Dimario, Francis. / Behavior and social competency in idiopathic and cryptogenic childhood epilepsy. In: Developmental Medicine and Child Neurology. 2007 ; Vol. 49, No. 7. pp. 487-492.
@article{bd5e23d45867447782bfdc1e4f030e6f,
title = "Behavior and social competency in idiopathic and cryptogenic childhood epilepsy",
abstract = "Behavioral and related disorders are frequently reported in association with childhood epilepsy but the reasons for this are unclear. In a long-term prospective, community-based study of newly-diagnosed childhood epilepsy, behavioral assessments (Child Behavior Checklist) were performed in children 8 to 9 years after the initial diagnosis of epilepsy to determine the impact of remission and medication status on behavioral problems. Children with epilepsy were also compared with sibling controls. A total of 226 children (108 females, 118 males; mean age 13y 1mo [SD 2y 8mo], range 8-17y) with idiopathic or cryptogenic epilepsy were included in the analyses. One hundred and twenty-eight matched pairs were included in analyses of case-sibling differences. Lack of remission and current medication use were associated with worse behavioral problem and competency scores. Lack of remission generally had a greater effect than medication use, except for attention problems; medication status had the more deleterious effect (p<0.001). Children with epilepsy had significantly worse behavioral problems and competency scores relative to sibling controls. Even in paris in which the patient was seizure-free and off medication, significant case-sibling differences persisted for most scales (p=0.05 to p=0.001). Lack of remission and continued use of antiepileptic drugs have a negative influence on behavioral problems in children with epilepsy but do not fully explain the worse scores relative to siblings. This suggests an independent effect associated with the epilepsy itself.",
author = "Berg, {Anne T.} and Vickrey, {Barbara G.} and Testa, {Francine M.} and Levy, {Susan R.} and Shlomo Shinnar and Francis Dimario",
year = "2007",
month = "7",
doi = "10.1111/j.1469-8749.2007.00487.x",
language = "English (US)",
volume = "49",
pages = "487--492",
journal = "Developmental Medicine and Child Neurology",
issn = "0012-1622",
publisher = "Wiley-Blackwell",
number = "7",

}

TY - JOUR

T1 - Behavior and social competency in idiopathic and cryptogenic childhood epilepsy

AU - Berg, Anne T.

AU - Vickrey, Barbara G.

AU - Testa, Francine M.

AU - Levy, Susan R.

AU - Shinnar, Shlomo

AU - Dimario, Francis

PY - 2007/7

Y1 - 2007/7

N2 - Behavioral and related disorders are frequently reported in association with childhood epilepsy but the reasons for this are unclear. In a long-term prospective, community-based study of newly-diagnosed childhood epilepsy, behavioral assessments (Child Behavior Checklist) were performed in children 8 to 9 years after the initial diagnosis of epilepsy to determine the impact of remission and medication status on behavioral problems. Children with epilepsy were also compared with sibling controls. A total of 226 children (108 females, 118 males; mean age 13y 1mo [SD 2y 8mo], range 8-17y) with idiopathic or cryptogenic epilepsy were included in the analyses. One hundred and twenty-eight matched pairs were included in analyses of case-sibling differences. Lack of remission and current medication use were associated with worse behavioral problem and competency scores. Lack of remission generally had a greater effect than medication use, except for attention problems; medication status had the more deleterious effect (p<0.001). Children with epilepsy had significantly worse behavioral problems and competency scores relative to sibling controls. Even in paris in which the patient was seizure-free and off medication, significant case-sibling differences persisted for most scales (p=0.05 to p=0.001). Lack of remission and continued use of antiepileptic drugs have a negative influence on behavioral problems in children with epilepsy but do not fully explain the worse scores relative to siblings. This suggests an independent effect associated with the epilepsy itself.

AB - Behavioral and related disorders are frequently reported in association with childhood epilepsy but the reasons for this are unclear. In a long-term prospective, community-based study of newly-diagnosed childhood epilepsy, behavioral assessments (Child Behavior Checklist) were performed in children 8 to 9 years after the initial diagnosis of epilepsy to determine the impact of remission and medication status on behavioral problems. Children with epilepsy were also compared with sibling controls. A total of 226 children (108 females, 118 males; mean age 13y 1mo [SD 2y 8mo], range 8-17y) with idiopathic or cryptogenic epilepsy were included in the analyses. One hundred and twenty-eight matched pairs were included in analyses of case-sibling differences. Lack of remission and current medication use were associated with worse behavioral problem and competency scores. Lack of remission generally had a greater effect than medication use, except for attention problems; medication status had the more deleterious effect (p<0.001). Children with epilepsy had significantly worse behavioral problems and competency scores relative to sibling controls. Even in paris in which the patient was seizure-free and off medication, significant case-sibling differences persisted for most scales (p=0.05 to p=0.001). Lack of remission and continued use of antiepileptic drugs have a negative influence on behavioral problems in children with epilepsy but do not fully explain the worse scores relative to siblings. This suggests an independent effect associated with the epilepsy itself.

UR - http://www.scopus.com/inward/record.url?scp=34347378673&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34347378673&partnerID=8YFLogxK

U2 - 10.1111/j.1469-8749.2007.00487.x

DO - 10.1111/j.1469-8749.2007.00487.x

M3 - Article

VL - 49

SP - 487

EP - 492

JO - Developmental Medicine and Child Neurology

JF - Developmental Medicine and Child Neurology

SN - 0012-1622

IS - 7

ER -