Bacterial infection in the acquired immunodeficiency syndrome of children

Larry J. Bernstein, Ben Zion Krieger, Brian Novick, Marc J. Sicklick, Arye Rubinstein

Research output: Chapter in Book/Report/Conference proceedingChapter

142 Citations (Scopus)

Abstract

We have followed 46 children with acquired immunodeficiency syndrome and acquired im-munodeficiency syndrome-related complex. Twenty-six patients had at least one episode of serious bacterial infection. Twenty-seven episodes of sepsis were documented in 21 patients. Soft tissue infection was common in both the presence and the absence of documented bacteremia. Urinary tract infection commonly presented as worsening diarrhea in the absence of sepsis. Organisms commonly isolated included Streptococcus pneumoniae, Haemophilus influenzae and Salmonella sp. Staphylococcal infection accompanied episodes of cellulitis/abscess. Escherichia coli commonly caused urinary tract infection in the absence of sepsis. Enteric and nosocomial sepsis was limited to hospitalized, instrumented patients or to individuals who had received prior antibiotic therapy as outpatients. We conclude that bacterial infection causes serious morbidity in acquired immunodeficiency syndrome and acquired immunodeficiency syndrome-related complex and may be further evidence for altered humoral immunity in the disorder.

Original languageEnglish (US)
Title of host publicationPediatric Infectious Disease
Pages472-475
Number of pages4
Volume4
Edition5
StatePublished - 1985

Fingerprint

Bacterial Infections
Sepsis
Acquired Immunodeficiency Syndrome
Urinary Tract Infections
Staphylococcal Infections
Soft Tissue Infections
Cellulitis
Haemophilus influenzae
Humoral Immunity
Bacteremia
Streptococcus pneumoniae
Salmonella
Abscess
Diarrhea
Outpatients
Escherichia coli
Anti-Bacterial Agents
Morbidity
Therapeutics

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)
  • Infectious Diseases

Cite this

Bernstein, L. J., Krieger, B. Z., Novick, B., Sicklick, M. J., & Rubinstein, A. (1985). Bacterial infection in the acquired immunodeficiency syndrome of children. In Pediatric Infectious Disease (5 ed., Vol. 4, pp. 472-475)

Bacterial infection in the acquired immunodeficiency syndrome of children. / Bernstein, Larry J.; Krieger, Ben Zion; Novick, Brian; Sicklick, Marc J.; Rubinstein, Arye.

Pediatric Infectious Disease. Vol. 4 5. ed. 1985. p. 472-475.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bernstein, LJ, Krieger, BZ, Novick, B, Sicklick, MJ & Rubinstein, A 1985, Bacterial infection in the acquired immunodeficiency syndrome of children. in Pediatric Infectious Disease. 5 edn, vol. 4, pp. 472-475.
Bernstein LJ, Krieger BZ, Novick B, Sicklick MJ, Rubinstein A. Bacterial infection in the acquired immunodeficiency syndrome of children. In Pediatric Infectious Disease. 5 ed. Vol. 4. 1985. p. 472-475
Bernstein, Larry J. ; Krieger, Ben Zion ; Novick, Brian ; Sicklick, Marc J. ; Rubinstein, Arye. / Bacterial infection in the acquired immunodeficiency syndrome of children. Pediatric Infectious Disease. Vol. 4 5. ed. 1985. pp. 472-475
@inbook{0e39cfbf45a742c08e6616b17efd9fe8,
title = "Bacterial infection in the acquired immunodeficiency syndrome of children",
abstract = "We have followed 46 children with acquired immunodeficiency syndrome and acquired im-munodeficiency syndrome-related complex. Twenty-six patients had at least one episode of serious bacterial infection. Twenty-seven episodes of sepsis were documented in 21 patients. Soft tissue infection was common in both the presence and the absence of documented bacteremia. Urinary tract infection commonly presented as worsening diarrhea in the absence of sepsis. Organisms commonly isolated included Streptococcus pneumoniae, Haemophilus influenzae and Salmonella sp. Staphylococcal infection accompanied episodes of cellulitis/abscess. Escherichia coli commonly caused urinary tract infection in the absence of sepsis. Enteric and nosocomial sepsis was limited to hospitalized, instrumented patients or to individuals who had received prior antibiotic therapy as outpatients. We conclude that bacterial infection causes serious morbidity in acquired immunodeficiency syndrome and acquired immunodeficiency syndrome-related complex and may be further evidence for altered humoral immunity in the disorder.",
author = "Bernstein, {Larry J.} and Krieger, {Ben Zion} and Brian Novick and Sicklick, {Marc J.} and Arye Rubinstein",
year = "1985",
language = "English (US)",
volume = "4",
pages = "472--475",
booktitle = "Pediatric Infectious Disease",
edition = "5",

}

TY - CHAP

T1 - Bacterial infection in the acquired immunodeficiency syndrome of children

AU - Bernstein, Larry J.

AU - Krieger, Ben Zion

AU - Novick, Brian

AU - Sicklick, Marc J.

AU - Rubinstein, Arye

PY - 1985

Y1 - 1985

N2 - We have followed 46 children with acquired immunodeficiency syndrome and acquired im-munodeficiency syndrome-related complex. Twenty-six patients had at least one episode of serious bacterial infection. Twenty-seven episodes of sepsis were documented in 21 patients. Soft tissue infection was common in both the presence and the absence of documented bacteremia. Urinary tract infection commonly presented as worsening diarrhea in the absence of sepsis. Organisms commonly isolated included Streptococcus pneumoniae, Haemophilus influenzae and Salmonella sp. Staphylococcal infection accompanied episodes of cellulitis/abscess. Escherichia coli commonly caused urinary tract infection in the absence of sepsis. Enteric and nosocomial sepsis was limited to hospitalized, instrumented patients or to individuals who had received prior antibiotic therapy as outpatients. We conclude that bacterial infection causes serious morbidity in acquired immunodeficiency syndrome and acquired immunodeficiency syndrome-related complex and may be further evidence for altered humoral immunity in the disorder.

AB - We have followed 46 children with acquired immunodeficiency syndrome and acquired im-munodeficiency syndrome-related complex. Twenty-six patients had at least one episode of serious bacterial infection. Twenty-seven episodes of sepsis were documented in 21 patients. Soft tissue infection was common in both the presence and the absence of documented bacteremia. Urinary tract infection commonly presented as worsening diarrhea in the absence of sepsis. Organisms commonly isolated included Streptococcus pneumoniae, Haemophilus influenzae and Salmonella sp. Staphylococcal infection accompanied episodes of cellulitis/abscess. Escherichia coli commonly caused urinary tract infection in the absence of sepsis. Enteric and nosocomial sepsis was limited to hospitalized, instrumented patients or to individuals who had received prior antibiotic therapy as outpatients. We conclude that bacterial infection causes serious morbidity in acquired immunodeficiency syndrome and acquired immunodeficiency syndrome-related complex and may be further evidence for altered humoral immunity in the disorder.

UR - http://www.scopus.com/inward/record.url?scp=0021881431&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021881431&partnerID=8YFLogxK

M3 - Chapter

C2 - 3900944

AN - SCOPUS:0021881431

VL - 4

SP - 472

EP - 475

BT - Pediatric Infectious Disease

ER -