Automatic localization of the prostatic urethra for image guided radiation therapy

Nicola J. Nasser; Jonathan Klein; Eyal Fenig; Abed Agbarya

doi:10.1016/j.tipsro.2021.05.002

Automatic localization of the prostatic urethra for image guided radiation therapy

Nicola J. Nasser, Jonathan Klein, Eyal Fenig, Abed Agbarya

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

Abstract

Treatment of prostate cancer with radiation therapy (RT) requires image guided RT (IGRT) to focus the radiation on the target volumes while minimizing doses to organs at risk. Here we describe a urinary catheter that allows imaging of the prostatic urethra and uses it for automatic localization of the prostate for IGRT. The catheter has a contrast lumen that can be empty or full with contrast. Computerized tomography is performed twice, with contrast lumen empty and full, allowing urethral autosegmentation using digital subtraction. Under ultrasound, continuous urethral visualization is possible by pumping aerated gel in- and out of the contrast lumen.

Original language	English (US)
Pages (from-to)	1-6
Number of pages	6
Journal	Technical Innovations and Patient Support in Radiation Oncology
Volume	19
DOIs	https://doi.org/10.1016/j.tipsro.2021.05.002
State	Published - Sep 2021

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Care Planning
Oncology(nursing)
Health Policy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tipsro.2021.05.002

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title = "Automatic localization of the prostatic urethra for image guided radiation therapy",

abstract = "Treatment of prostate cancer with radiation therapy (RT) requires image guided RT (IGRT) to focus the radiation on the target volumes while minimizing doses to organs at risk. Here we describe a urinary catheter that allows imaging of the prostatic urethra and uses it for automatic localization of the prostate for IGRT. The catheter has a contrast lumen that can be empty or full with contrast. Computerized tomography is performed twice, with contrast lumen empty and full, allowing urethral autosegmentation using digital subtraction. Under ultrasound, continuous urethral visualization is possible by pumping aerated gel in- and out of the contrast lumen.",

author = "Nasser, {Nicola J.} and Jonathan Klein and Eyal Fenig and Abed Agbarya",

note = "Funding Information: The authors would like to thank Ms. Terry Helms from the office of Design and Creative Services of the Memorial Sloan Kettering Cancer Center for crafting the Nasser – Zelefsky US catheter drawings based on description provided by the author (N.J.N.). The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: N.J.N. declare being an inventor on a patent application filed by the Memorial Sloan-Kettering Cancer Center (MSKCC) about the catheters described in the manuscript. US provisional application number 62/142,032, International Application Number PCT/US2016/025607, International Publication Number WO2016/161313A1. N.J.N. have a license agreement with MSKCC regarding this invention. J.K. E.F. A.A. declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Publisher Copyright: {\textcopyright} 2021 The Author(s)",

year = "2021",

month = sep,

doi = "10.1016/j.tipsro.2021.05.002",

language = "English (US)",

volume = "19",

pages = "1--6",

journal = "Technical Innovations and Patient Support in Radiation Oncology",

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TY - JOUR

T1 - Automatic localization of the prostatic urethra for image guided radiation therapy

AU - Nasser, Nicola J.

AU - Klein, Jonathan

AU - Fenig, Eyal

AU - Agbarya, Abed

N1 - Funding Information: The authors would like to thank Ms. Terry Helms from the office of Design and Creative Services of the Memorial Sloan Kettering Cancer Center for crafting the Nasser – Zelefsky US catheter drawings based on description provided by the author (N.J.N.). The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: N.J.N. declare being an inventor on a patent application filed by the Memorial Sloan-Kettering Cancer Center (MSKCC) about the catheters described in the manuscript. US provisional application number 62/142,032, International Application Number PCT/US2016/025607, International Publication Number WO2016/161313A1. N.J.N. have a license agreement with MSKCC regarding this invention. J.K. E.F. A.A. declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Publisher Copyright: © 2021 The Author(s)

PY - 2021/9

Y1 - 2021/9

N2 - Treatment of prostate cancer with radiation therapy (RT) requires image guided RT (IGRT) to focus the radiation on the target volumes while minimizing doses to organs at risk. Here we describe a urinary catheter that allows imaging of the prostatic urethra and uses it for automatic localization of the prostate for IGRT. The catheter has a contrast lumen that can be empty or full with contrast. Computerized tomography is performed twice, with contrast lumen empty and full, allowing urethral autosegmentation using digital subtraction. Under ultrasound, continuous urethral visualization is possible by pumping aerated gel in- and out of the contrast lumen.

AB - Treatment of prostate cancer with radiation therapy (RT) requires image guided RT (IGRT) to focus the radiation on the target volumes while minimizing doses to organs at risk. Here we describe a urinary catheter that allows imaging of the prostatic urethra and uses it for automatic localization of the prostate for IGRT. The catheter has a contrast lumen that can be empty or full with contrast. Computerized tomography is performed twice, with contrast lumen empty and full, allowing urethral autosegmentation using digital subtraction. Under ultrasound, continuous urethral visualization is possible by pumping aerated gel in- and out of the contrast lumen.

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JO - Technical Innovations and Patient Support in Radiation Oncology

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ER -

Automatic localization of the prostatic urethra for image guided radiation therapy

Abstract

ASJC Scopus subject areas

UN SDGs

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