TY - JOUR
T1 - Atypical ST-Segment-Elevation Myocardial Infarction Presentation in Patients With COVID-19 at a High-Volume Center in New York City
AU - Villela, Miguel A.Alvarez
AU - Alkhalil, Ahmad
AU - Weinreich, Michael A.
AU - Koslowsky, Jonathan
AU - Aoi, Shunsuke
AU - Latib, M. Azeem
N1 - Publisher Copyright:
© 2021 by the Texas Heart® Institute, Houston.
PY - 2021
Y1 - 2021
N2 - Atypical presentations of ST-segment-elevation myocardial infarction (STEMI) have been reported in patients who have COVID-19. We have seen this occurrence in our center in Bronx, New York, where multitudes of patients sought treatment for the coronavirus. We studied the prevalence of atypical STEMI findings among patients with COVID-19 who presented during the first 2 months of the pandemic. Consistent with previous reports, 4 of our 10 patients with COVID-19 and STEMI had no identifiable culprit coronary lesion; rather, they often had diffuse ST-segment elevations on surface electrocardiograms along with higher levels of D-dimer and inflammatory markers. In contrast, 32 of 33 patients without COVID-19 (97%) had a culprit lesion. The patients with COVID-19 and a culprit lesion more often needed thrombectomy catheterization and administration of glycoprotein IIb/IIIa inhibitors. Our study confirms that patients with COVID-19 often have atypical STEMI presentations, including the frequent absence of a culprit coronary lesion. Our findings can help clinicians prepare for these atypical clinical presentations.
AB - Atypical presentations of ST-segment-elevation myocardial infarction (STEMI) have been reported in patients who have COVID-19. We have seen this occurrence in our center in Bronx, New York, where multitudes of patients sought treatment for the coronavirus. We studied the prevalence of atypical STEMI findings among patients with COVID-19 who presented during the first 2 months of the pandemic. Consistent with previous reports, 4 of our 10 patients with COVID-19 and STEMI had no identifiable culprit coronary lesion; rather, they often had diffuse ST-segment elevations on surface electrocardiograms along with higher levels of D-dimer and inflammatory markers. In contrast, 32 of 33 patients without COVID-19 (97%) had a culprit lesion. The patients with COVID-19 and a culprit lesion more often needed thrombectomy catheterization and administration of glycoprotein IIb/IIIa inhibitors. Our study confirms that patients with COVID-19 often have atypical STEMI presentations, including the frequent absence of a culprit coronary lesion. Our findings can help clinicians prepare for these atypical clinical presentations.
KW - COVID-19
KW - Cardiovascular dis-eases/physiopathology
KW - Coronary angiography
KW - Coronavirus infections/ diagnosis
KW - Retrospective studies
KW - ST elevation myocar-dial infarction/complica-tions/epidemiology
KW - Time-to-treatment
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UR - http://www.scopus.com/inward/citedby.url?scp=85122103882&partnerID=8YFLogxK
U2 - 10.14503/THIJ-20-7446
DO - 10.14503/THIJ-20-7446
M3 - Article
C2 - 34913970
AN - SCOPUS:85122103882
SN - 0730-2347
VL - 48
JO - Texas Heart Institute Journal
JF - Texas Heart Institute Journal
IS - 5
M1 - e207446
ER -