Astrocytic oxidative/nitrosative stress contributes to parkinson’s disease pathogenesis: The dual role of reactive astrocytes

Agriculture & Biology

• Parkinson disease 99%
• astrocytes 88%
• pathogenesis 66%
• oxidative stress 57%
• etiology 25%
• toxic substances 23%
• reactive nitrogen species 16%
• rotenone 15%
• neurodegenerative diseases 15%
• paraquat 13%
• neuroglia 13%
• central nervous system 12%
• environmental impact 11%
• manganese 11%
• inflammation 11%
• phosphotransferases (kinases) 10%
• neurons 10%
• reactive oxygen species 10%
• genes 8%
• mutation 8%
• antioxidants 7%
• proteins 4%

Medicine & Life Sciences

• Nitrosative Stress 100%
• Astrocytes 67%
• Parkinson Disease 61%
• Oxidative Stress 53%
• Protein Deglycase DJ-1 20%
• Synucleins 18%
• Rotenone 16%
• Paraquat 16%
• Reactive Nitrogen Species 16%
• Pars Compacta 15%
• 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 15%
• Manganese 14%
• Neuroglia 10%
• Neurodegenerative Diseases 10%
• Theoretical Models 9%
• Genes 9%
• Reactive Oxygen Species 9%
• Phosphotransferases 9%
• Antioxidants 9%
• Central Nervous System 9%
• Neurons 7%
• Inflammation 7%
• Mutation 6%

Chemical Compounds

• 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 19%
• Rotenone 17%
• Reactive Nitrogen Species 16%
• Paraquat 16%
• Detoxification 13%
• Oxidative Stress 12%
• Reactive Oxygen Metabolite 11%
• Mutation 10%
• Metabolic 9%
• Antioxidant Agent 9%
• Protein 5%