Assessment of seizure risk in pre-clinical studies

Strengths and limitations of the electroencephalogram (EEG)

Monica Metea, Mona Litwak, Joseph C. Arezzo

Research output: Contribution to journalArticle

6 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)135-142
Number of pages8
JournalJournal of Pharmacological and Toxicological Methods
Volume75
DOIs
StatePublished - Sep 1 2015

Fingerprint

Telemetering
Electroencephalography
Animals

Keywords

  • Convulsions
  • EEG spectral analysis
  • Electromyography/EMG
  • Preclinical seizure risk assessment
  • Premonitory signs
  • Regulatory drug development
  • Safety pharmacology
  • Seizure
  • Sharp waves
  • Telemetry
  • Tremors
  • Video-EEG

ASJC Scopus subject areas

  • Pharmacology
  • Toxicology

Cite this

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title = "Assessment of seizure risk in pre-clinical studies: Strengths and limitations of the electroencephalogram (EEG)",
keywords = "Convulsions, EEG spectral analysis, Electromyography/EMG, Preclinical seizure risk assessment, Premonitory signs, Regulatory drug development, Safety pharmacology, Seizure, Sharp waves, Telemetry, Tremors, Video-EEG",
author = "Monica Metea and Mona Litwak and Arezzo, {Joseph C.}",
year = "2015",
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pages = "135--142",
journal = "Journal of Pharmacological and Toxicological Methods",
issn = "1056-8719",
publisher = "Elsevier Inc.",

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T1 - Assessment of seizure risk in pre-clinical studies

T2 - Strengths and limitations of the electroencephalogram (EEG)

AU - Metea, Monica

AU - Litwak, Mona

AU - Arezzo, Joseph C.

PY - 2015/9/1

Y1 - 2015/9/1

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KW - EEG spectral analysis

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KW - Premonitory signs

KW - Regulatory drug development

KW - Safety pharmacology

KW - Seizure

KW - Sharp waves

KW - Telemetry

KW - Tremors

KW - Video-EEG

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U2 - 10.1016/j.vascn.2015.04.001

DO - 10.1016/j.vascn.2015.04.001

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EP - 142

JO - Journal of Pharmacological and Toxicological Methods

JF - Journal of Pharmacological and Toxicological Methods

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