Assessing minimal residual disease (MRD) in leukemia: A changing definition and concept?

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The term minimal residual disease (MRD) in its currently accepted application refers to low-level disease detected in a whole variety of clinical situations. It is used to describe residual disease after suboptimal induction chemotherapy, but at the same time refers to the lowest levels of disease potentially compatible with cure or to molecularly defined relapse after long-term remission. This discussion intends to redefine MRD into some biologically relevant subcategories which may warrant their own independent terminology.

Original languageEnglish (US)
Pages (from-to)459-465
Number of pages7
JournalBone Marrow Transplantation
Volume29
Issue number6
DOIs
StatePublished - 2002
Externally publishedYes

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Residual Neoplasm
Leukemia
Induction Chemotherapy
Terminology
Recurrence

Keywords

  • Minimal residual disease
  • New definitions

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Assessing minimal residual disease (MRD) in leukemia : A changing definition and concept? / Paietta, Elisabeth M.

In: Bone Marrow Transplantation, Vol. 29, No. 6, 2002, p. 459-465.

Research output: Contribution to journalArticle

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