Arterial and venous thrombelastograph® variables differ during cardiac surgery

Heather E. Manspeizer, Mayuko Imai, Robert J. Frumento, Michael K. Parides, Berend Mets, Elliott Bennett-Guerrero

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The Thrombelastograph® (TEG®; Haemoscope Corp., Skokie, IL) coagulation analyzer is an effective point-of-care monitor for routine clinical practice and clinical research. Prior investigators have used either arterial or venous samples of blood for TEG® measurements. We conducted this prospective cohort study to determine potential differences in TEG® variables between arterial and venous blood samples. Arterial and venous samples were drawn from 40 cardiac surgical patients, yielding 134 pairs for comparison. Twenty-nine comparisons (control) were between arterial and arterial samples and were not significantly different. For the arterial and venous comparisons (n = 105), mean (±SD) arterial and venous values were the following: reaction time, 10 ± 2 mm vs 13 ± 4 mm, P = 0.004; maximum amplitude, 59 ± 9 mm vs 49 ± 12 mm, P < 0.001; α angle, 61 ± 10 degrees vs 51 ± 14 degrees, P < 0.001; K, 5 ± 2 mm vs 8 ± 4 mm, P = 0.007; and lysis, 2.5 ± 1.7 vs 2.5 ± 2.0 (not significant), arterial versus venous, respectively. Arterial blood samples demonstrated TEG® values reflecting stronger (larger maximum amplitude) and faster (shorter reaction time and K value, wider α angle) clot formation. The results suggest that users of TEG® coagulation analyzers should be consistent with the site of blood sampling given the potential differences obtained.

Original languageEnglish (US)
Pages (from-to)277-281
Number of pages5
JournalAnesthesia and Analgesia
Volume93
Issue number2
StatePublished - Aug 14 2001
Externally publishedYes

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Thoracic Surgery
Point-of-Care Systems
Cohort Studies
Research Personnel
Prospective Studies
Research

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Manspeizer, H. E., Imai, M., Frumento, R. J., Parides, M. K., Mets, B., & Bennett-Guerrero, E. (2001). Arterial and venous thrombelastograph® variables differ during cardiac surgery. Anesthesia and Analgesia, 93(2), 277-281.

Arterial and venous thrombelastograph® variables differ during cardiac surgery. / Manspeizer, Heather E.; Imai, Mayuko; Frumento, Robert J.; Parides, Michael K.; Mets, Berend; Bennett-Guerrero, Elliott.

In: Anesthesia and Analgesia, Vol. 93, No. 2, 14.08.2001, p. 277-281.

Research output: Contribution to journalArticle

Manspeizer, HE, Imai, M, Frumento, RJ, Parides, MK, Mets, B & Bennett-Guerrero, E 2001, 'Arterial and venous thrombelastograph® variables differ during cardiac surgery', Anesthesia and Analgesia, vol. 93, no. 2, pp. 277-281.
Manspeizer HE, Imai M, Frumento RJ, Parides MK, Mets B, Bennett-Guerrero E. Arterial and venous thrombelastograph® variables differ during cardiac surgery. Anesthesia and Analgesia. 2001 Aug 14;93(2):277-281.
Manspeizer, Heather E. ; Imai, Mayuko ; Frumento, Robert J. ; Parides, Michael K. ; Mets, Berend ; Bennett-Guerrero, Elliott. / Arterial and venous thrombelastograph® variables differ during cardiac surgery. In: Anesthesia and Analgesia. 2001 ; Vol. 93, No. 2. pp. 277-281.
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