Aptamers and aptamer targeted delivery

Amy C. Yan, Matthew Levy

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

When aptamers first emerged almost two decades ago, most were RNA species that bound and tagged or inhibited simple target ligands. Very soon after, the 'selectionologists' developing aptamer technology quickly realized more potential for the aptamer. In recent years, advances in aptamer techniques have enabled the use of aptamers as small molecule inhibitors, diagnostic tools and even therapeutics. Aptamers are now being employed in novel applications. We review, herein, some of the recent and exciting applications of aptamers in cell-specific recognition and delivery.

Original languageEnglish (US)
Pages (from-to)106-110
Number of pages5
JournalRNA Biology
Volume6
Issue number3
StatePublished - Jul 2009

Fingerprint

RNA
Ligands
Technology
Therapeutics

Keywords

  • Aptamers
  • In vitro selection
  • SELEX
  • siRNA delivery
  • Targeted delivery

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Cite this

Yan, A. C., & Levy, M. (2009). Aptamers and aptamer targeted delivery. RNA Biology, 6(3), 106-110.

Aptamers and aptamer targeted delivery. / Yan, Amy C.; Levy, Matthew.

In: RNA Biology, Vol. 6, No. 3, 07.2009, p. 106-110.

Research output: Contribution to journalArticle

Yan, AC & Levy, M 2009, 'Aptamers and aptamer targeted delivery', RNA Biology, vol. 6, no. 3, pp. 106-110.
Yan AC, Levy M. Aptamers and aptamer targeted delivery. RNA Biology. 2009 Jul;6(3):106-110.
Yan, Amy C. ; Levy, Matthew. / Aptamers and aptamer targeted delivery. In: RNA Biology. 2009 ; Vol. 6, No. 3. pp. 106-110.
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