Abstract
When aptamers first emerged almost two decades ago, most were RNA species that bound and tagged or inhibited simple target ligands. Very soon after, the 'selectionologists' developing aptamer technology quickly realized more potential for the aptamer. In recent years, advances in aptamer techniques have enabled the use of aptamers as small molecule inhibitors, diagnostic tools and even therapeutics. Aptamers are now being employed in novel applications. We review, herein, some of the recent and exciting applications of aptamers in cell-specific recognition and delivery.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 316-320 |
| Number of pages | 5 |
| Journal | RNA biology |
| Volume | 6 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2009 |
| Externally published | Yes |
Keywords
- Aptamers
- In vitro selection
- SELEX
- Targeted delivery
- siRNA delivery
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology