Anterior ischaemic optic neuropathy and intraocular pressure

Barrett Katz, R. N. Weinreb, D. T. Wheeler, M. R. Klauber

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Anterior ischaemic optic neuropathy is a stroke syndrome of the distal optic nerve, characterised by disc oedema and optic nerve dysfunction - loss of central vision, loss of colour vision, a relative afferent pupillary defect, and nerve fibre layer field loss. We prospectively evaluated the changes of intraocular pressure throughout the day in 16 patients with non-arteritic anterior ischaemic optic neuropathy and 15 normal control subjects of similar age and race. The peak intraocular pressure exceeded 21 mm Hg in five of the ischaemic optic neuropathy patients but none of the controls. The mean peak intraocular pressure was 19.9 mm Hg for the ischaemic optic neuropathy group versus 17.6 mm Hg for controls (p = 0.034). The range of intraocular pressure was also greater for the ischaemic optic neuropathy group (p = 0.030). Eight of 16 ischaemic optic neuropathy patients had a range of intraocular pressure of 6 mm Hg or more, compared with three of 15 control subjects. The intraocular pressure exceeded 21 mm Hg during a subsequent visit in two additional patients in whom the hourly determined intraocular pressure peaked at less than 21 mm Hg. Thus, seven of 16 of our ischaemic optic neuropathy group had an intraocular pressure exceeding 21 mm Hg during the study period. Raised intraocular pressure may be a predisposing factor in some patients who develop anterior ischaemic optic neuropathy.

Original languageEnglish (US)
Pages (from-to)99-102
Number of pages4
JournalBritish Journal of Ophthalmology
Volume74
Issue number2
StatePublished - 1990
Externally publishedYes

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Ischemic Optic Neuropathy
Intraocular Pressure
Optic Nerve
Pupil Disorders
Color Vision
Nerve Fibers
Causality
Edema
Stroke

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Katz, B., Weinreb, R. N., Wheeler, D. T., & Klauber, M. R. (1990). Anterior ischaemic optic neuropathy and intraocular pressure. British Journal of Ophthalmology, 74(2), 99-102.

Anterior ischaemic optic neuropathy and intraocular pressure. / Katz, Barrett; Weinreb, R. N.; Wheeler, D. T.; Klauber, M. R.

In: British Journal of Ophthalmology, Vol. 74, No. 2, 1990, p. 99-102.

Research output: Contribution to journalArticle

Katz, B, Weinreb, RN, Wheeler, DT & Klauber, MR 1990, 'Anterior ischaemic optic neuropathy and intraocular pressure', British Journal of Ophthalmology, vol. 74, no. 2, pp. 99-102.
Katz, Barrett ; Weinreb, R. N. ; Wheeler, D. T. ; Klauber, M. R. / Anterior ischaemic optic neuropathy and intraocular pressure. In: British Journal of Ophthalmology. 1990 ; Vol. 74, No. 2. pp. 99-102.
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