Anesthetic Management of a Pediatric Patient With Pelizaeus-Merzbacher Syndrome: A Case Report

Roshan S. Patel, Madelyn Kahana

Research output: Contribution to journalArticle


A 3-year-old pediatric patient with previously diagnosed Pelizaeus-Merzbacher syndrome presented for outpatient dental restoration. Given the infrequency of this demyelinating disorder, an anesthetic plan was tailored to address the patient's hypotonia and aspiration risk, as well as minimize potential complications including seizures, hemodynamic instability, and postoperative respiratory support. Multimodal analgesia, along with an appropriate ventilation strategy and normothermia, allowed the patient to successfully undergo a general anesthetic and be safely discharged home the same day.

Original languageEnglish (US)
Pages (from-to)351-352
Number of pages2
JournalA&A practice
Issue number12
Publication statusPublished - Dec 15 2018


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