An audit of adverse events in children sedated with chloral hydrate or propofol during imaging studies

CRAIG MEROLA, CYNTHIA ALBARRACIN, PHILIP LEBOWITZ, ROBERT S. BIENKOWSKI, SAMUEL M. BARST

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

We examined records of sedations provided by the paediatric anaesthesiology staff for 455 children (ages 1 mo‐17 yr) undergoing MRI or CT scans at our institution over a twelve‐month period with regard to the monitoring of adverse events: excessive sedation, agitation, vomiting, hypoxaemia, and major airway compromise. One hundred‐and‐thirty‐one patients (29%) received chloral hydrate; 324 patients (71%) received propofol. All patients were monitored with continuous noninvasive pulse oximetry and received supplemental oxygen via nasal cannulae. Of the patients who received chloral hydrate, 64 (49%) were over one year of age; of the patients who received propofol, 318 (98%) were one year of age or older. In the chloral hydrate group, 23 patients (19%) were deemed excessively sedated and four patients (3%) were agitated; no patients in the propofol group experienced any of the adverse outcomes reviewed. Furthermore, no patients in either group had significant airway compromise and none was admitted to the hospital as a result of the sedation.

Original languageEnglish (US)
Pages (from-to)375-378
Number of pages4
JournalPediatric Anesthesia
Volume5
Issue number6
DOIs
StatePublished - Nov 1995

Keywords

  • CT
  • MRI
  • chloral hydrate
  • propofol

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anesthesiology and Pain Medicine

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    MEROLA, CRAIG., ALBARRACIN, CYNTHIA., LEBOWITZ, PHILIP., BIENKOWSKI, ROBERT. S., & BARST, SAMUEL. M. (1995). An audit of adverse events in children sedated with chloral hydrate or propofol during imaging studies. Pediatric Anesthesia, 5(6), 375-378. https://doi.org/10.1111/j.1460-9592.1995.tb00330.x