TY - JOUR
T1 - Adherence to pharmacotherapy and medication-related beliefs in patients with hypertension in Lima, Peru
AU - Fernandez-Arias, Marta
AU - Acuna-Villaorduna, Ana
AU - Miranda, J. Jaime
AU - Diez-Canseco, Francisco
AU - Malaga, German
N1 - Publisher Copyright:
© 2014 Fernandez-Arias et al.
PY - 2014/12/3
Y1 - 2014/12/3
N2 - Objective: To characterize adherence to pharmacological medication and beliefs towards medication in a group of patients with hypertension in a large national hospital.Materials and Methods: Cross-sectional survey among patients with hypertension attending the outpatient clinic of a large national hospital. Exposure of interest was the patient's beliefs towards general medication and antihypertensive drugs, i.e. beliefs of harm, overuse, necessity and concern, measured using the Beliefs about Medication questionnaire. Main outcome was adherence measured using the Morisky Medication Adherence Scale-8. Multivariate analysis was conducted using Poisson distribution logistic regression, prevalence ratios and 95% confidence intervals were calculated.Results: Data from 115 participants, 67% females and mean age 62.7 years were analyzed. Low adherence was found in 57.4%. Highest scores were on the ideas of necessity and one of the most rated statements was "physicians would prescribe less medication if they spent more time with patients". Beliefs of harm about medications and concerns about antihypertensive drugs were higher in the low adherence group (p<0.01). Those who scored higher on ideas of harm were 52% less likely of being high adherents (PR 0.48; 95% CI 0.25-0.93) and those with higher scores on concerns were 41% less likely of being high adherents (PR 0.59; 95% CI 0.39-0.91). Patients whose ideas of necessity outweighed their concerns were more likely to be adherent (PR 2.65; 95% CI 1.21-5.81).Conclusions: Low adherence to antihypertensive medication is common. High scores on ideas of harm, concern and a high necessity-concern differential were predictors of medication adherence.
AB - Objective: To characterize adherence to pharmacological medication and beliefs towards medication in a group of patients with hypertension in a large national hospital.Materials and Methods: Cross-sectional survey among patients with hypertension attending the outpatient clinic of a large national hospital. Exposure of interest was the patient's beliefs towards general medication and antihypertensive drugs, i.e. beliefs of harm, overuse, necessity and concern, measured using the Beliefs about Medication questionnaire. Main outcome was adherence measured using the Morisky Medication Adherence Scale-8. Multivariate analysis was conducted using Poisson distribution logistic regression, prevalence ratios and 95% confidence intervals were calculated.Results: Data from 115 participants, 67% females and mean age 62.7 years were analyzed. Low adherence was found in 57.4%. Highest scores were on the ideas of necessity and one of the most rated statements was "physicians would prescribe less medication if they spent more time with patients". Beliefs of harm about medications and concerns about antihypertensive drugs were higher in the low adherence group (p<0.01). Those who scored higher on ideas of harm were 52% less likely of being high adherents (PR 0.48; 95% CI 0.25-0.93) and those with higher scores on concerns were 41% less likely of being high adherents (PR 0.59; 95% CI 0.39-0.91). Patients whose ideas of necessity outweighed their concerns were more likely to be adherent (PR 2.65; 95% CI 1.21-5.81).Conclusions: Low adherence to antihypertensive medication is common. High scores on ideas of harm, concern and a high necessity-concern differential were predictors of medication adherence.
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U2 - 10.1371/journal.pone.0112875
DO - 10.1371/journal.pone.0112875
M3 - Article
C2 - 25470372
AN - SCOPUS:84916203344
SN - 1932-6203
VL - 9
JO - PloS one
JF - PloS one
IS - 12
M1 - e0112875
ER -