Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins

G. B. Evans; R. H. Furneaux; T. L. Hutchison; H. S. Kezar; Jr E. Morris; V. L. Schramm; P. C. Tyler

doi:10.1021/jo0155613

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins

G. B. Evans, R. H. Furneaux, T. L. Hutchison, H. S. Kezar, Jr E. Morris, V. L. Schramm, P. C. Tyler

Biochemistry

Research output: Contribution to journal › Article › peer-review

97 Scopus citations

Abstract

Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.

Original language	English (US)
Pages (from-to)	5723-5730
Number of pages	8
Journal	Journal of Organic Chemistry
Volume	66
Issue number	17
DOIs	https://doi.org/10.1021/jo0155613
State	Published - Aug 24 2001

ASJC Scopus subject areas

Organic Chemistry

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10.1021/jo0155613

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title = "Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins",

abstract = "Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.",

author = "Evans, {G. B.} and Furneaux, {R. H.} and Hutchison, {T. L.} and Kezar, {H. S.} and Morris, {Jr E.} and Schramm, {V. L.} and Tyler, {P. C.}",

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T2 - Convergent synthesis of the aza-C-nucleoside immucillins

AU - Evans, G. B.

AU - Furneaux, R. H.

AU - Hutchison, T. L.

AU - Kezar, H. S.

AU - Morris, Jr E.

AU - Schramm, V. L.

AU - Tyler, P. C.

PY - 2001/8/24

Y1 - 2001/8/24

N2 - Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.

AB - Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.

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Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins

Abstract

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