Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine

Convergent synthesis of the aza-C-nucleoside immucillins

G. B. Evans, R. H. Furneaux, T. L. Hutchison, H. S. Kezar, Jr E. Morris, Vern L. Schramm, P. C. Tyler

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.

Original languageEnglish (US)
Pages (from-to)5723-5730
Number of pages8
JournalJournal of Organic Chemistry
Volume66
Issue number17
DOIs
StatePublished - Aug 24 2001

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Imines
Nucleosides
Carbohydrates
Derivatives

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine : Convergent synthesis of the aza-C-nucleoside immucillins. / Evans, G. B.; Furneaux, R. H.; Hutchison, T. L.; Kezar, H. S.; Morris, Jr E.; Schramm, Vern L.; Tyler, P. C.

In: Journal of Organic Chemistry, Vol. 66, No. 17, 24.08.2001, p. 5723-5730.

Research output: Contribution to journalArticle

Evans, G. B. ; Furneaux, R. H. ; Hutchison, T. L. ; Kezar, H. S. ; Morris, Jr E. ; Schramm, Vern L. ; Tyler, P. C. / Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine : Convergent synthesis of the aza-C-nucleoside immucillins. In: Journal of Organic Chemistry. 2001 ; Vol. 66, No. 17. pp. 5723-5730.
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