Acute lung injury

Michelle Ng Gong, David C. Christiani

Research output: Chapter in Book/Report/Conference proceedingChapter


The acute respiratory distress syndrome (ARDS)/acute lung injury is a major cause of morbidity and mortality throughout the world. ARDS is an acute syndrome of lung inflammation and increased permeability associated with severe hypoxia and bilateral infiltrates on chest radiographs with no evidence of left heart failure. This chapter reviews the evidence for genetic determinants in acute lung injury and ARDS with a focus on potential candidate gene polymorphism that may be important in the development and outcome of ARDS.

Original languageEnglish (US)
Title of host publicationPrinciples of Molecular Medicine
PublisherHumana Press
Number of pages8
ISBN (Print)9781588292025
StatePublished - Dec 1 2006
Externally publishedYes


  • Acute lung injury (ALI)
  • acute respiratory distress
  • angiotensin-converting enzyme (ACE)
  • glutathnione-S-transferase (GST)
  • syndrome (ARDS)

ASJC Scopus subject areas

  • Medicine(all)


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