Acute eosinophilic pneumonia associated with shock

Venkata L. Buddharaju, Joseph L. Saraceno, Jonathan M. Rosen, Simon D. Spivack, Thomas C. Smith, Riivo Ilves, Donald A. Killam, Barbara J. McKenna

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Objective: To describe an unusual case of acute eosinophilic pneumonia (AEP) associated with hemodynamic instability. Design: Case report, clinical. Settings: Tertiary care intensive care unit (ICU). Patient: A single patient admitted to the ICU. Interventions: Intravenous corticosteroids. Measurements and Main Results: Resolution of distributive shock and respiratory failure. Conclusions: AEP with respiratory failure was first reported in 1989 as a distinct clinical entity. Patients with this variant of eosinophilic lung disease develop acute hypoxemic respiratory failure with a rapid response to treatment with corticosteroids. The characteristic feature of this syndrome is a predominance of eosinophils found in bronchoalveolar lavage fluid and lung biopsy. Despite the increasing number of reported cases, to our knowledge, distributive shock has not been reported as a feature of AEP. We report a unique case of AEP associated with shock and review the pertinent literature.

Original languageEnglish (US)
Pages (from-to)2014-2016
Number of pages3
JournalCritical care medicine
Volume27
Issue number9
DOIs
StatePublished - Oct 7 1999

Keywords

  • Eosinophilic
  • Interleukins
  • Pneumonia
  • Shock

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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    Buddharaju, V. L., Saraceno, J. L., Rosen, J. M., Spivack, S. D., Smith, T. C., Ilves, R., Killam, D. A., & McKenna, B. J. (1999). Acute eosinophilic pneumonia associated with shock. Critical care medicine, 27(9), 2014-2016. https://doi.org/10.1097/00003246-199909000-00048