A twin study of self-regulatory eating in early childhood

Estimates of genetic and environmental influence, and measurement considerations

M. S. Faith, A. Pietrobelli, Moonseong Heo, S. L. Johnson, K. L. Keller, S. B. Heymsfield, D. B. Allison

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: Children differ greatly in their ability to self-regulate food intake for reasons that are poorly understood. This laboratory-based twin study tested the genetic and environmental contributions to self-regulatory eating and body fat in early childhood. Methods: A total of 69 4-7 year-old same-sex twin pairs, including 40 monozygotic and 29 dizygotic pairs, were studied. Self-regulatory eating was operationalized as the percentage compensation index (COMPX%), assessed by a preload challenge in which lunch intake was measured following a low-(3 kcal) or high-calorie (159 kcal) drink. Body fat indexes also were measured. The familial association for COMPX% was estimated by an intraclass correlation, and biometric analyses estimated heritability. Results: Children ate more at lunch following the low-compared with high-energy preload (P<0.001), although variability in COMPX% was considerable. Compensation was significantly poorer among African American and Hispanic compared with European American children, and among girls compared with boys. There was a familial association for self-regulatory eating (p=0.23, P=0.03) but no significant genetic component. In all, 22% of the variance in COMPX% was due to shared environmental household factors, with the remaining variance attributable to child-specific unique or random environments. Poorer self-regulatory eating was associated with greater percent body fat (r=-0.21, P=0.04). Conclusions: Self-regulatory eating was influenced by environmental factors, especially those differing among siblings. The absence of a significant genetic effect may reflect the age of the sample or could be artifactual due to measurement issues that need to be considered in future studies.

Original languageEnglish (US)
Pages (from-to)931-937
Number of pages7
JournalInternational Journal of Obesity
Volume36
Issue number7
DOIs
StatePublished - Jul 2012

Fingerprint

Twin Studies
Eating
Adipose Tissue
Lunch
Aptitude
Hispanic Americans
African Americans
Siblings

Keywords

  • behavior genetics
  • compensation
  • heritability
  • pediatric obesity
  • self-regulatory eating
  • twins

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Endocrinology, Diabetes and Metabolism

Cite this

A twin study of self-regulatory eating in early childhood : Estimates of genetic and environmental influence, and measurement considerations. / Faith, M. S.; Pietrobelli, A.; Heo, Moonseong; Johnson, S. L.; Keller, K. L.; Heymsfield, S. B.; Allison, D. B.

In: International Journal of Obesity, Vol. 36, No. 7, 07.2012, p. 931-937.

Research output: Contribution to journalArticle

Faith, M. S. ; Pietrobelli, A. ; Heo, Moonseong ; Johnson, S. L. ; Keller, K. L. ; Heymsfield, S. B. ; Allison, D. B. / A twin study of self-regulatory eating in early childhood : Estimates of genetic and environmental influence, and measurement considerations. In: International Journal of Obesity. 2012 ; Vol. 36, No. 7. pp. 931-937.
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