A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury

Mark K. Lyons, Michael D. Partington, Fredric B. Meyer, Gary M. Yarkony, Elliot J. Roth, Moris Senegor, Henry G. Stifel, Margaret Brown, Michael B. Bracken, Mary jo Shepard, William F. Collins, Theodore R. Holford, Wise Young, Joseph Piepmeier, Linda Leo-Summers, David S. Baskin, Howard M. Eisenberg, Eugene Flamm, Lawrence F. Marshall, Joseph MaroonJack Wilberger, Phanor L. Perot, Volker K.h. Sonntag, Franklin C. Wagner, H. Richard Winn

Research output: Contribution to journalLetter

5 Scopus citations

Abstract

To the Editor: After reading the recent article by Bracken et al. (May 17 issue),1 we have several questions regarding data not discussed that would facilitate our analysis of this very important work. First, we understand from the description of the neurologic examination that proprioceptive function was not recorded and that in patients with a “complete” injury, proprioception may have been intact. A recent study suggests that the presence or absence of proprioception is strongly predictive of neurologic outcome in patients with acute spinal-cord injury.2 Bracken et al.3 reported previously that a complete sensory examination (including tests of proprioception) was.

Original languageEnglish (US)
Pages (from-to)1207-1209
Number of pages3
JournalNew England Journal of Medicine
Volume323
Issue number17
DOIs
StatePublished - Oct 25 1990

ASJC Scopus subject areas

  • Medicine(all)

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    Lyons, M. K., Partington, M. D., Meyer, F. B., Yarkony, G. M., Roth, E. J., Senegor, M., Stifel, H. G., Brown, M., Bracken, M. B., Shepard, M. J., Collins, W. F., Holford, T. R., Young, W., Piepmeier, J., Leo-Summers, L., Baskin, D. S., Eisenberg, H. M., Flamm, E., Marshall, L. F., ... Winn, H. R. (1990). A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. New England Journal of Medicine, 323(17), 1207-1209. https://doi.org/10.1056/NEJM199010253231712