A New Quassinoid from Brucea javanica

Jun Li; Dayong Zheng; Ning Wei; Yunfeng Sun; Li Liu; Yuan Yuan; Qinghua Jiang

doi:10.1007/s10600-022-03762-2

A New Quassinoid from Brucea javanica

Jun Li, Dayong Zheng, Ning Wei, Yunfeng Sun, Li Liu, Yuan Yuan, Qinghua Jiang

Research output: Contribution to journal › Article › peer-review

Abstract

A new quassinoid, dehydrobruceantinol B (1), was isolated from the seeds of Brucea javanica, together with two known compounds, bruceantinol (2) and bruceine A (3). The structure of the new compound 1 was elucidated by advanced spectrometric methods, including HR-MS, UV, IR, 1D and 2D NMR experiments. The inhibitory effects of 1–3 on nitric oxide production in lipopolysaccharide-activated macrophages were also investigated in this study.

Original language	English (US)
Pages (from-to)	650-652
Number of pages	3
Journal	Chemistry of Natural Compounds
Volume	58
Issue number	4
DOIs	https://doi.org/10.1007/s10600-022-03762-2
State	Published - Jul 2022
Externally published	Yes

Keywords

Brucea javanica
Simaroubaceae
nitric oxide production
quassinoid

ASJC Scopus subject areas

General Chemistry
General Biochemistry, Genetics and Molecular Biology
Plant Science

Access to Document

10.1007/s10600-022-03762-2

Cite this

@article{44c87cdf58bd4dc38df2d1139ea61f71,

title = "A New Quassinoid from Brucea javanica",

abstract = "A new quassinoid, dehydrobruceantinol B (1), was isolated from the seeds of Brucea javanica, together with two known compounds, bruceantinol (2) and bruceine A (3). The structure of the new compound 1 was elucidated by advanced spectrometric methods, including HR-MS, UV, IR, 1D and 2D NMR experiments. The inhibitory effects of 1–3 on nitric oxide production in lipopolysaccharide-activated macrophages were also investigated in this study.",

keywords = "Brucea javanica, Simaroubaceae, nitric oxide production, quassinoid",

author = "Jun Li and Dayong Zheng and Ning Wei and Yunfeng Sun and Li Liu and Yuan Yuan and Qinghua Jiang",

note = "Publisher Copyright: {\textcopyright} 2022, Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2022",

month = jul,

doi = "10.1007/s10600-022-03762-2",

language = "English (US)",

volume = "58",

pages = "650--652",

journal = "Chemistry of Natural Compounds",

issn = "0009-3130",

publisher = "Springer New York",

number = "4",

}

TY - JOUR

T1 - A New Quassinoid from Brucea javanica

AU - Li, Jun

AU - Zheng, Dayong

AU - Wei, Ning

AU - Sun, Yunfeng

AU - Liu, Li

AU - Yuan, Yuan

AU - Jiang, Qinghua

PY - 2022/7

Y1 - 2022/7

N2 - A new quassinoid, dehydrobruceantinol B (1), was isolated from the seeds of Brucea javanica, together with two known compounds, bruceantinol (2) and bruceine A (3). The structure of the new compound 1 was elucidated by advanced spectrometric methods, including HR-MS, UV, IR, 1D and 2D NMR experiments. The inhibitory effects of 1–3 on nitric oxide production in lipopolysaccharide-activated macrophages were also investigated in this study.

AB - A new quassinoid, dehydrobruceantinol B (1), was isolated from the seeds of Brucea javanica, together with two known compounds, bruceantinol (2) and bruceine A (3). The structure of the new compound 1 was elucidated by advanced spectrometric methods, including HR-MS, UV, IR, 1D and 2D NMR experiments. The inhibitory effects of 1–3 on nitric oxide production in lipopolysaccharide-activated macrophages were also investigated in this study.

KW - Brucea javanica

KW - Simaroubaceae

KW - nitric oxide production

KW - quassinoid

UR - http://www.scopus.com/inward/record.url?scp=85136120339&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85136120339&partnerID=8YFLogxK

U2 - 10.1007/s10600-022-03762-2

DO - 10.1007/s10600-022-03762-2

M3 - Article

AN - SCOPUS:85136120339

SN - 0009-3130

VL - 58

SP - 650

EP - 652

JO - Chemistry of Natural Compounds

JF - Chemistry of Natural Compounds

IS - 4

ER -

A New Quassinoid from Brucea javanica

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this