A comparison of transcutaneous PO2 in patients sedated with diazepam-fentanyl or midazolam-fentanyl

Stephen H. Sutley, Lieutenant Colonel, Richard A. Kraut

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Fifty oral and maxillofacial surgery patients undergoing outpatient surgical removal of third molars under intravenous conscious sedation comprised the study group. All patients received 1 μg/kg of fentanyl prior to receiving either diazepam or midazolam. The results show no statistically significant differences in blood pressure or pulse over time between the two groups, nor was there a statistically significant difference between the transcutaneous PO2 responses of the groups. However, a statistically significant time effect as well as a group by time interaction was present. Both groups show respiratory depression at the 8- and 10-minute time intervals. The use of supplemental oxygen and monitoring of respiration is recommended with the use of these drug combinations.

Original languageEnglish (US)
Pages (from-to)93-97
Number of pages5
JournalAnesthesia Progress
Volume36
Issue number3
StatePublished - May 1989
Externally publishedYes

Fingerprint

Midazolam
Fentanyl
Diazepam
Oral Surgery
Conscious Sedation
Third Molar
Drug Combinations
Respiratory Insufficiency
Respiration
Outpatients
Oxygen
Blood Pressure

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

A comparison of transcutaneous PO2 in patients sedated with diazepam-fentanyl or midazolam-fentanyl. / Sutley, Stephen H.; Colonel, Lieutenant; Kraut, Richard A.

In: Anesthesia Progress, Vol. 36, No. 3, 05.1989, p. 93-97.

Research output: Contribution to journalArticle

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