Fifty oral and maxillofacial surgery patients undergoing outpatient surgical removal of third molars under intravenous conscious sedation comprised the study group. All patients received 1 μg/kg of fentanyl prior to receiving either diazepam or midazolam. The results show no statistically significant differences in blood pressure or pulse over time between the two groups, nor was there a statistically significant difference between the transcutaneous PO2 responses of the groups. However, a statistically significant time effect as well as a group by time interaction was present. Both groups show respiratory depression at the 8- and 10-minute time intervals. The use of supplemental oxygen and monitoring of respiration is recommended with the use of these drug combinations.
|Original language||English (US)|
|Number of pages||5|
|Publication status||Published - May 1 1989|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine