SIGNALING PATHWAYS &TRANSCRIPTIONAL REGULATION

Project: Research project

Project Details

Description

DESCRIPTION(adapted from applicant's abstract): Transcription of the large
ribosomal RNAs and ribosomal protein mRNAs account for more than 70 percent of
nuclear transcription and must be under tight control to prevent their
energetically costly synthesis at inappropriate times. The transcription of
these ribosomal RNAs is coordinately regulated to ensure the synthesis of
stoichiometric amounts of ribosomal components and optimal levels of protein
synthetic substrates. And prevent their energetically costly synthesis at
inappropriate times. The long term goal of the proposed application is to
elucidate the relationship between cell proliferation and transcription of the
protein synthetic machinery.
StatusFinished
Effective start/end date7/1/006/30/01

Funding

  • National Institute of General Medical Sciences: $268,000.00

ASJC

  • Genetics
  • Molecular Biology
  • Cell Biology
  • Microbiology
  • Organic Chemistry

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