HEMATOPOIESIS IN RETROVIRUS INFECTED SIMIANS

  • Mani, Sridhar (PI)
  • Reimann, Keith (PI)
  • Weiss, Ned M. (PI)
  • Goldberg, Leon (PI)
  • Schuster, Charles (PI)
  • Rabinovich, C. Egla (PI)
  • Kremser, Cynthia (PI)
  • Buse, John (PI)
  • Solway, Julian (PI)
  • Josephson, Michelle (PI)
  • Asplin, John (PI)
  • Herbst, Arthur L. (PI)
  • Lashner, Bret (PI)
  • Mazzone, Theodore (PI)
  • Kreiter, Mary (PI)
  • Dewit, Harriet (PI)
  • Brown, Frederick D. (PI)
  • Scoeller, Dale (PI)
  • Rajfer, Sol (PI)
  • Pononsky, Kenneth (PI)
  • Richman, David (PI)
  • Douglas, Frank L. (PI)
  • Baron, Joseph M. (PI)
  • Thistlethwaite, J. Richard (PI)
  • Jones, Thomas (PI)
  • Meltzer, Herbert Yale (PI)
  • Johanson, Chris E. (PI)
  • Aycinena, P. (PI)
  • Chelmickaschorr, E.V.A. (PI)
  • Rosenberg, Irwin (PI)
  • Arcilla, Rene (PI)
  • Zacny, James (PI)
  • Roos, Raymond P. (PI)
  • Polansky, Kenneth (PI)
  • Scany, Angelo M. (PI)
  • Tartof, David (PI)
  • Davidson, Nicholas (PI)
  • Lichtor, J. Lance (PI)
  • Knowles, Jarol B. (PI)
  • Jonas, Richard B. (PI)
  • January, Craig (PI)
  • Hall, Jesse (PI)
  • Roizan, Nancy (PI)
  • Voke, Tamara (PI)
  • Cara, Jose (PI)
  • Cuttler, Leona (PI)
  • Senay, Edward (PI)
  • Beebe, Christine A. (PI)
  • Loy, Gary (PI)
  • Palonsky, Kenneth S. (PI)
  • Huttenlocher, Peter (PI)
  • Barron, William M. (PI)
  • Kaplan, Edward (PI)
  • Benca, Ruth (PI)
  • Antel, Jack (PI)
  • Murphy, Michael B. (PI)
  • Degroot, Leslie (PI)
  • Baker, Alfred L. (PI)
  • Schueller, Dale (PI)
  • Cohen, Louis (PI)
  • Burstein, Stephen (PI)
  • Roizen, Nancy (PI)
  • Fellner, Susan K. (PI)
  • Samuels, Brian (PI)
  • Sommerfeld, Eberhard (PI)
  • Lau, Kai (PI)
  • Kaplan, Edwin (PI)
  • Landau, Richard (PI)
  • Kirschner, Barbara (PI)
  • Saper, Clifford (PI)
  • Hopkins, Joyce (PI)
  • Reder, Anthony T. (PI)
  • Berkelhammer, Charles (PI)
  • Rose, Robert P. (PI)
  • Apfelbaum, Jeffrey (PI)
  • Jonghorbani, Morteza (PI)
  • Schuette, Sally (PI)
  • Pliskin, Neil (PI)
  • Scanu, Angelo (PI)
  • Sarne, David (PI)
  • Moll, George W. (PI)
  • Robertson, Gary L. (PI)
  • Goldman, Morris (PI)
  • Crayton, John (PI)
  • Sitrin, Michael (PI)
  • Golomb, Harvey (PI)
  • Richards, Jon (PI)
  • Jaspar, Jonathan (PI)
  • Little, Alex G. (PI)
  • Jaspan, Jonathan B. (PI)
  • Bergenstal, Richard (PI)
  • Rubenstein, Arthur H. (PI)
  • Roizen, Michael (PI)
  • Lang, Roberto (PI)
  • Cura, Jose (PI)
  • Rolzen, Michael (PI)
  • Fang, Victor S. (PI)
  • Lindheimer, Marshall (PI)
  • Chait, Larry (PI)
  • Whitington, Peter (PI)
  • King, Donald (PI)
  • Yost, Michael (PI)
  • Hellman, Samuel (PI)
  • Arnason, Barry (PI)
  • Sarpong, Sampson (PI)
  • Johnson, Daniel (PI)
  • Draganich, Louis Frank (PI)
  • McClintock, Martha (PI)
  • Ndukwu, I. (PI)
  • Getz, Godfrey Shalom (PI)
  • Keenan, Kathryn Elizabeth (PI)
  • Steele, Glenn (PI)
  • Murray, Patrick (PI)
  • Kindler, Hedy (PI)
  • Conjeevaram, Hari (PI)
  • Olopade, Olufunmilayo (PI)
  • McNally, Beth (PI)
  • Ratain, Mark (PI)
  • Kyle, John (PI)
  • King, Andrea (PI)
  • Yuan, Chun- (PI)
  • Vogelzang, Nicholas (PI)
  • Ehrenpreis, Eli (PI)
  • Cook, Edwin (PI)
  • Weir, Bryce (PI)
  • [No Value], Frederick L. (PI)
  • Vokes, Tamara (PI)
  • Madara, James (PI)
  • Vokes, Everett (PI)
  • Woodle, E. Steve (PI)
  • Covert, Robert (PI)
  • Ehrman, David (PI)
  • Lauderdale, Diane (PI)
  • Gajewski, Thomas (PI)
  • Ober, Carole (PI)
  • McBurnett, Keith (PI)
  • Clark, Marcus (PI)
  • Brady, Lynda (PI)
  • Rosenfield, Robert (PI)
  • Brady, Lynda (PI)
  • Ober, Carole (PI)
  • Hanauer, Stephen B. (PI)
  • McBurnett, Keith (PI)
  • Keenan, Kathryn Elizabeth (PI)
  • Murray, Patrick (PI)
  • van Cauter, E.V.E. (PI)
  • Kindler, Hedy (PI)
  • Rabinovich, Consuelo Diana (PI)
  • Conjeevaram, Hari (PI)
  • Lauderdale, Diane (PI)
  • Refetoff, Samuel (PI)
  • Schilsky, Richard (PI)
  • Weiss, Roy (PI)
  • Olopade, Olufunmilayo (PI)
  • Bell, Graeme (PI)
  • Ehrman, David (PI)
  • Polonsky, Kenneth (PI)
  • McNally, Beth (PI)
  • De, Harriet (PI)
  • Barnes, Randall (PI)
  • Ehramann, David (PI)
  • Ratain, Mark (PI)
  • Cho, Judy (PI)
  • Clark, Marcus (PI)
  • Gajewski, Thomas (PI)
  • Kyle, John (PI)
  • King, Andrea (PI)
  • Yuan, Chun- (PI)
  • Vogelzang, Nicholas (PI)
  • Ehrenpreis, Eli (PI)
  • Cook, Edwin (PI)
  • Favus, Murray (PI)
  • Ehrmann, David (PI)
  • David, Frank (PI)
  • Refetoff, Samuel (PI)
  • Sokoloff, Mitchell (PI)
  • Phillipson, Leslie (PI)
  • Hall, Jesse B. (PI)
  • Radovick, Sally (PI)
  • Vogelzang, Nicholas (PI)
  • Kim, Karen (PI)
  • Dachman, Abraham (PI)
  • Owley, Thomas (PI)
  • Alverdy, John C. (PI)
  • Mc Closkey, Michael (PI)
  • Te, Helen (PI)
  • Rosenfield, Robert (PI)
  • Garfinkel, Marc (PI)
  • Cocca, Emil Frank (PI)
  • McConville, John (PI)
  • Ober, Carole (PI)
  • White, Steven (PI)
  • van Cauter, E.V.E. (PI)
  • Weiss, Roy (PI)
  • McNally, Elizabeth (PI)
  • Royce, Lee (PI)
  • Lipton, Rebecca B. (PI)
  • De, Harriet (PI)
  • Cho, Judy (PI)
  • Penev, Plamen (PI)
  • King, Andrea (PI)
  • Yuan, Chun- (PI)
  • Ehrmann, David (PI)
  • Philipson, Louis H. (PI)
  • Favus, Murray (PI)
  • Burnett, Deborah (PI)
  • Utset, Tammy (PI)
  • Ratain, Mark (PI)
  • Sperling, Anne I. (PI)
  • Stephenson, Mary (PI)
  • Lahn, Bruce (PI)
  • Noth, Imre (PI)
  • Phan, K. Luan (PI)
  • Refetoff, Samuel (PI)
  • Pannain, Silvana (PI)
  • Nicolae, Dan Liviu (PI)
  • Gomberg-Maitland, Mardi (PI)
  • Bell, Graeme (PI)
  • [No Value], Nancy J. (PI)
  • Burnet, Deborah (PI)
  • Tasali, Esra (PI)
  • Olopade, Funmi (PI)
  • Clark, Marcus (PI)
  • Maitland, Michael L. (PI)
  • Le Grange, Daniel (PI)
  • Kusher, Robert (PI)
  • Byrne, Maria (PI)
  • Clarke, Bart (PI)
  • Umans, Jason (PI)
  • Ober, Carole (PI)
  • Aikens, James (PI)
  • Herold, Kevan (PI)
  • Schoeller, Dale A. (PI)
  • Gerber, Glenn (PI)
  • Lichtor, J. (PI)
  • Wagner-Weiner, Linda (PI)
  • Yurk, Helene (PI)
  • Scholler, Dale (PI)
  • Albert, Daniel (PI)
  • Fleming, Gini (PI)
  • Bartosh, Sharon (PI)
  • Kushner, Robert F. (PI)
  • Foss, Joseph (PI)
  • Rosenfield, Robert L. (PI)
  • Hanauer, Stephen (PI)
  • Favus, Murray J. (PI)
  • van Cauter, E.V.E. (PI)
  • Rabinovich, Consuelo Diana (PI)
  • Refetoff, Samuel (PI)
  • Schilsky, Richard (PI)
  • Weiss, Roy (PI)
  • Bell, Graeme (PI)
  • Polonsky, Kenneth (PI)
  • De, Harriet (PI)
  • Barnes, Randall B. (PI)
  • Ehramann, David (PI)
  • Cho, Judy (PI)
  • Ehrmann, David (PI)
  • Weiss, Ned M. (PI)
  • Rabinovich, C. Egla (PI)
  • Herbst, Arthur L. (PI)
  • Brown, Frederick D. (PI)
  • Douglas, Frank L. (PI)
  • Baron, Joseph M. (PI)
  • Thistlethwaite, J. Richard (PI)
  • Johanson, Chris E. (PI)
  • Chelmickaschorr, E.V.A. (PI)
  • Roos, Raymond P. (PI)
  • Scany, Angelo M. (PI)
  • Lichtor, J. Lance (PI)
  • Knowles, Jarol B. (PI)
  • Jonas, Richard B. (PI)
  • Beebe, Christine A. (PI)
  • Palonsky, Kenneth S. (PI)
  • Barron, William M. (PI)
  • Aycinena, P. (PI)
  • Murphy, Michael B. (PI)
  • Baker, Alfred L. (PI)
  • Robertson, Gary L. (PI)
  • Fellner, Susan K. (PI)
  • Reder, Anthony T. (PI)
  • Fang, Victor S. (PI)
  • Rose, Robert P. (PI)
  • Moll, George W. (PI)
  • Little, Alex G. (PI)
  • Jaspan, Jonathan B. (PI)
  • Rubenstein, Arthur H. (PI)
  • Ndukwu, I. (PI)
  • [No Value], Frederick L. (PI)
  • Woodle, E. Steve (PI)
  • Hanauer, Stephen B. (PI)
  • van Cauter, E.V.E. (PI)
  • Hall, Jesse B. (PI)
  • Alverdy, John C. (PI)
  • van Cauter, E.V.E. (PI)
  • Lipton, Rebecca B. (PI)
  • Sperling, Anne I. (PI)
  • Phan, K. Luan (PI)
  • [No Value], Nancy J. (PI)
  • Maitland, Michael L. (PI)
  • Dachman, Abraham (PI)
  • Owley, Thomas (PI)
  • Alverdy, John C. (PI)
  • Mc Closkey, Michael (PI)
  • Te, Helen (PI)
  • Rosenfield, Robert (PI)
  • Garfinkel, Marc (PI)
  • Cocca, Emil Frank (PI)
  • McConville, John (PI)
  • Coe, Frederic (PI)
  • Ober, Carole (PI)
  • White, Steven (PI)
  • van Cauter, E.V.E. (PI)
  • Weiss, Roy (PI)
  • McNally, Elizabeth (PI)
  • Royce, Lee (PI)
  • Lipton, Rebecca B. (PI)
  • De, Harriet (PI)
  • Cho, Judy (PI)
  • Vokes, Tamara (PI)
  • Penev, Plamen (PI)
  • King, Andrea (PI)
  • Yuan, Chun- (PI)
  • Ehrmann, David (PI)
  • Kusher, Robert (PI)
  • Byrne, Maria (PI)
  • Clarke, Bart (PI)
  • Umans, Jason (PI)
  • Ober, Carole (PI)
  • Aikens, James (PI)
  • Herold, Kevan (PI)
  • Schoeller, Dale A. (PI)
  • Gerber, Glenn (PI)
  • Lichtor, J. (PI)
  • Wagner-Weiner, Linda (PI)
  • Yurk, Helene (PI)
  • Scholler, Dale (PI)
  • Albert, Daniel (PI)
  • Fleming, Gini (PI)
  • Bartosh, Sharon (PI)
  • Kushner, Robert F. (PI)
  • Foss, Joseph (PI)
  • Rosenfield, Robert L. (PI)
  • Hanauer, Stephen (PI)
  • Favus, Murray J. (PI)
  • van Cauter, E.V.E. (PI)
  • Rabinovich, Consuelo Diana (PI)
  • Refetoff, Samuel (PI)
  • Schilsky, Richard (PI)
  • Weiss, Roy (PI)
  • Bell, Graeme (PI)
  • Polonsky, Kenneth (PI)
  • De, Harriet (PI)
  • Barnes, Randall B. (PI)
  • Ehramann, David (PI)
  • Cho, Judy (PI)
  • Ehrmann, David (PI)

Project: Research project

Project Details

Description

This research proposal is to establish the macaque monkey as a model for
studying normal primate hematopoiesis. During years 1-3, the
distribution of lymphocyte subsets within bone marrow, lymph node,
spleen, and peripheral blood compartments will be compared and the
maturation and turnover of specific subsets of cells will be assessed
using cell cycle analysis and dual fluorescence flow cytometry. These
techniques, together with assays to assess maturation of cells of the
monocytic/granulocytic series will be employed to study the
hematopathology associated with type D retrovirus and SIV infection of
macaques. Studies during years 4 and 5 will extend the observations on
mechanisms of virus induced hematopathology and begin to explore
domestic species as models for hematopoiesis.
StatusFinished
Effective start/end date12/1/782/28/11

Funding

  • National Center for Research Resources
  • National Center for Research Resources

ASJC

  • Medicine(all)

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