ELECTROPHYSIOLOGIC STUDIES OF PSYCHOMOTER PROCESSES

Project: Research project

Description

This research project will define the intracortical patterns of neural
activity that underlie visual evoked potentials and the endogenous event
related potentials (ERP) associated with discriminative performance. Old
world monkeys will be employed as an animal model of human ERP generation.
Methods for concurrent recording of field potentials and multiple unit
activity (MUA), augmented by current source density (CSD) analysis will be
used to examine the effect of manipulating stimulus and task variables on
intracortical activity. These studies are intended to bridge the gap
between investigations of scalp recorded ERP in humans and the more
detailed analyses of intracortical activity that can only be carried out in
experimental animals.
StatusFinished
Effective start/end date4/1/786/30/95

Funding

  • National Institutes of Health: $318,513.00
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $297,453.00
  • National Institutes of Health

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Visual Cortex
Electrophysiology
Evoked Potentials
Cercopithecidae
Neurotransmitter Agents
Scalp
Bicuculline
Electrodes
Hand
GABA Antagonists
Injections
Neurons
gamma-Aminobutyric Acid
Brain
N-Methyl-D-Aspartate Receptors
Visual Evoked Potentials
Research
Haplorhini
Animal Models

ASJC

  • Medicine(all)