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Zhengdong Zhang, Ph.D.

  • 21182 Citations
  • 30 h-Index
20002022
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  • 5 Similar Profiles
Human Genome Medicine & Life Sciences
Genome Medicine & Life Sciences
Genes Medicine & Life Sciences
Mole Rats Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
Genomic Structural Variation Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
RNA Medicine & Life Sciences

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Grants 2007 2022

Resilience to Alzheimer's disease in humans with exceptional longevity

Barzilai, N. & Zhang, Z.

National Institutes of Health

9/15/17 → 5/31/22

Project: Research project

Alzheimer Disease
Genotype
Cognition
Genes
Research

Interpreting human enhancer variants with a network-regularized composite model

Zhang, Z.

National Institutes of Health

9/12/16 → 7/31/19

Project: Research project

Genes
Composite materials
Computational methods
Medical problems
Risk assessment

Comparative genomes of longevity

Vijg, J., Zhang, Z., Seluanov, A., Gladyshev, V. N. & Gorbunova, V.

National Institutes of Health

5/1/14 → 4/30/19

Project: Research project

Mutation Rate
Bioinformatics
Mutation
Rodentia
Genome

Gene regulation in metastasis and new methods to analyze its microarray profiles

Zhang, Z.

National Institutes of Health

9/30/07 → 9/29/14

Project: Research project

Microarray Analysis
Neoplasm Metastasis
Research
Genes
Neoplasms

Publications 2000 2019

  • 21182 Citations
  • 30 h-Index
  • 63 Article
  • 2 Conference contribution
  • 1 Comment/debate
4 Citations (Scopus)

SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

Tian, X., Firsanov, D., Zhang, Z., Cheng, Y., Luo, L., Tombline, G., Tan, R., Simon, M., Henderson, S., Steffan, J., Goldfarb, A., Tam, J., Zheng, K., Cornwell, A., Johnson, A., Yang, J. N., Mao, Z., Manta, B., Dang, W., Zhang, Z. & 8 others, Vijg, J., Wolfe, A., Moody, K., Kennedy, B. K., Bohmann, D., Gladyshev, V. N., Seluanov, A. & Gorbunova, V., Apr 18 2019, In : Cell. 177, 3, p. 622-638.e22

Research output: Contribution to journal › Article

Double-Stranded DNA Breaks
Rodentia
Repair
DNA
2 Citations (Scopus)

Epigenetic alterations to Polycomb targets precede malignant transition in a mouse model of breast cancer

Cai, Y., Lin, J. R., Zhang, Q., O'Brien, K., Montagna, C. & Zhang, Z., Dec 1 2018, In : Scientific Reports. 8, 1, 5535.

Research output: Contribution to journal › Article

Epigenomics
Breast Neoplasms
DNA Methylation
Neoplasms
Methylation
1 Citation (Scopus)

Global, integrated analysis of methylomes and transcriptomes from laser capture microdissected bronchial and alveolar cells in human lung

Dong, X., Shi, M., Lee, M., Toro, R., Gravina, S., Han, W., Yasuda, S., Wang, T., Zhang, Z., Vijg, J., Suh, Y. & Spivack, S. D., May 1 2018, (Accepted/In press) In : Epigenetics. p. 1-11 11 p.

Research output: Contribution to journal › Article

Alveolar Epithelial Cells
Gene Expression Profiling
Lasers
Lung
GTP Phosphohydrolases
4 Citations (Scopus)

HEDD: Human Enhancer Disease Database

Wang, Z., Zhang, Q., Zhang, W., Lin, J. R., Cai, Y., Mitra, J. & Zhang, Z., Jan 1 2018, In : Nucleic Acids Research. 46, D1, p. D113-D120

Research output: Contribution to journal › Article

Databases
Genes
Gene Regulatory Networks
Human Genome
1 Citation (Scopus)

PGA: Post-GWAS analysis for disease gene identification

Lin, J. R., Jaroslawicz, D., Cai, Y., Zhang, Q., Wang, Z. & Zhang, Z., May 15 2018, In : Bioinformatics. 34, 10, p. 1786-1788 3 p.

Research output: Contribution to journal › Article

Prostaglandins A
Genome-Wide Association Study
Genome
Genes
Gene