Projects per year
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Dive into the research topics where William R. Jacobs Jr. is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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TB Phage therapy: Optimizing delivery methods of mycobacteriophages to target intracellular Mycobacterium tuberculosis
12/7/20 → 11/30/21
Project: Research project
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Molecular Genetic Analysis of Mycobacterium Tuberculosis
National Institute of Allergy and Infectious Diseases
1/1/90 → 8/31/22
Project: Research project
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Shortening Tuberculosis Chemotherapies using N-acetylcysteine
6/15/18 → 5/31/20
Project: Research project
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Generation of a Complete Set of Precise Null Bar-Coded Deletion Mutants of Mycobacterium tuberculosis
9/14/17 → 8/31/21
Project: Research project
Publications
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A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis
Gupta, P., Thomas, S. E., Zaidan, S. A., Pasillas, M. A., Cory-Wright, J., Sebastián-Pérez, V., Burgess, A., Cattermole, E., Meghir, C., Abell, C., Coyne, A. G., Jacobs, W. R., Blundell, T. L., Tiwari, S. & Mendes, V., Jan 2021, In: Computational and Structural Biotechnology Journal. 19, p. 3491-3506 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A recombinant herpes virus expressing influenza hemagglutinin confers protection and induces antibody-dependent cellular cytotoxicity
Kaugars, K., Dardick, J., de Oliveira, A. P., Weiss, K. A., Lukose, R., Kim, J., Leung, L., Rajagopalan, S., Wolin, S., Akabas, L., Knipe, D. M., Bajic, G. & Jacobs, W. R., Aug 24 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 34, e2110714118.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Sterilization by adaptive immunity of a conditionally persistent mutant of mycobacterium tuberculosis
Vilchèze, C., Porcelli, S. A., Chan, J. & Jacobs, W. R., Jan 1 2021, In: mBio. 12, 1, p. 1-5 5 p., e02391-20.Research output: Contribution to journal › Article › peer-review
Open Access -
The promises and limitations of n-acetylcysteine as a potentiator of first-line and second-line tuberculosis drugs
Vilchèze, C. & Jacobs, W. R., May 2021, In: Antimicrobial agents and chemotherapy. 65, 5, e01703-20.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
3-(Phenethylamino)demethyl(oxy)aaptamine as an anti-dormant mycobacterial substance: Isolation, evaluation and total synthesis
Sumii, Y., Kotoku, N., Han, C., Kamiya, K., Setiawan, A., Vilchèze, C., Jacobs, W. R. & Arai, M., May 28 2020, In: Tetrahedron Letters. 61, 22, 151924.Research output: Contribution to journal › Article › peer-review
2 Scopus citations