Projects per year
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Dive into the research topics where William R. Jacobs Jr. is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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TB Phage therapy: Optimizing delivery methods of mycobacteriophages to target intracellular Mycobacterium tuberculosis
Jacobs, W. W. R. & Jacobs Jr., W. R.
National Institute of Allergy and Infectious Diseases
12/7/20 → 11/30/22
Project: Research project
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TB Phage therapy: Optimizing delivery methods of mycobacteriophages to target intracellular Mycobacterium tuberculosis
12/7/20 → 11/30/21
Project: Research project
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Shortening Tuberculosis Chemotherapies using N-acetylcysteine
6/15/18 → 5/31/20
Project: Research project
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Shortening Tuberculosis Chemotherapies using N-acetylcysteine
Jacobs Jr., W. R. & Jacobs, W. R.
National Institute of Allergy and Infectious Diseases
6/15/18 → 5/31/20
Project: Research project
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Generation of a Complete Set of Precise Null Bar-Coded Deletion Mutants of Mycobacterium tuberculosis
9/14/17 → 8/31/21
Project: Research project
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Commonalities of Mycobacterium tuberculosis Transcriptomes in Response to Defined Persisting Macrophage Stresses
Vilchèze, C., Yan, B., Casey, R., Hingley-Wilson, S., Ettwiller, L. & Jacobs, W. R., Jul 1 2022, In: Frontiers in immunology. 13, 909904.Research output: Contribution to journal › Article › peer-review
Open Access -
Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates
Wang, L., Asare, E., Shetty, A. C., Sanchez-Tumbaco, F., Edwards, M. R., Saranathan, R., Weinrick, B., Xu, J., Chen, B., Bénard, A., Dougan, G., Leung, D. W., Amarasinghe, G. K., Chan, J., Basler, C. F., Jacobs, W. R. & Tufariello, J. A. M., Feb 22 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 8, e2112608119.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis
Gupta, P., Thomas, S. E., Zaidan, S. A., Pasillas, M. A., Cory-Wright, J., Sebastián-Pérez, V., Burgess, A., Cattermole, E., Meghir, C., Abell, C., Coyne, A. G., Jacobs, W. R., Blundell, T. L., Tiwari, S. & Mendes, V., Jan 2021, In: Computational and Structural Biotechnology Journal. 19, p. 3491-3506 16 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
A recombinant herpes virus expressing influenza hemagglutinin confers protection and induces antibody-dependent cellular cytotoxicity
Kaugars, K., Dardick, J., de Oliveira, A. P., Weiss, K. A., Lukose, R., Kim, J., Leung, L., Rajagopalan, S., Wolin, S., Akabas, L., Knipe, D. M., Bajic, G. & Jacobs, W. R., Aug 24 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 34, e2110714118.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2
Báez-Ramírez, E., Querales, L., Aranaga, C. A., López, G., Guerrero, E., Kremer, L., Carrère-Kremer, S., Viljoen, A., Daffé, M., Laval, F., Cole, S. T., Benjak, A., Alzari, P., André-Leroux, G., Jacobs, W. R., Vilcheze, C. & Takiff, H. E., Dec 2021, In: Cell Surface. 7, 100060.Research output: Contribution to journal › Article › peer-review
Open Access