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  • 43 Similar Profiles
Acute Myeloid Leukemia Medicine & Life Sciences
Myelodysplastic Syndromes Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Genes Medicine & Life Sciences

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Grants 2008 2022

Stem Cells
Small Interfering RNA
Leukemia
Recurrence
Critical Pathways
Homeobox Genes
Acute Myeloid Leukemia
Transcription Factors
Leukemia
Critical Pathways

Transcriptional regulation of leukemic stem cells in acute myeloid leukemia

Steidl, U. G.

National Institutes of Health

9/1/084/30/12

Project: Research projectResearch Transition Award, Career Transition Award

Acute Myeloid Leukemia
Stem Cells
Leukemia
Transcription Factors
Maintenance

Publications 1998 2017

  • 3277 Citations
  • 35 h-Index
  • 97 Article
  • 3 Review article
  • 2 Short survey
  • 1 Chapter

A myeloid tumor suppressor role for NOL3

Stanley, R. F., Piszczatowski, R. T., Bartholdy, B., Mitchell, K., McKimpson, W. M., Narayanagari, S., Walter, D., Todorova, T. I., Hirsch, C., Makishima, H., Will, B., McMahon, C., Gritsman, K., Maciejewski, J. P., Kitsis, R. N. & Steidl, U. Mar 6 2017 In : The Journal of experimental medicine. 214, 3, p. 753-771 19 p.

Research output: Research - peer-reviewArticle

Neoplasms
Primary Myelofibrosis
Nuclear Proteins
Cyclin-Dependent Kinase 6
Cell Biology

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

Reyna, D. E., Garner, T. P., Lopez, A., Kopp, F., Choudhary, G. S., Sridharan, A., Narayanagari, S. R., Mitchell, K., Dong, B., Bartholdy, B. A., Walensky, L. D., Verma, A., Steidl, U. & Gavathiotis, E. Oct 9 2017 In : Cancer Cell. 32, 4, p. 490-505.e10

Research output: Research - peer-reviewArticle

Acute Myeloid Leukemia
Apoptosis
Proteins
Therapeutics
Myeloid Cells

Epigenetically aberrant stroma in MDS propagates disease via Wnt/β-catenin activation

Bhagat, T. D. , Chen, S. , Bartenstein, M. , Barlowe, A. T. , Von Ahrens, D. , Choudhary, G. S. , Tivnan, P. , Amin, E. , Marcondes, A. M. , Sanders, M. A. , Hoogenboezem, R. M. , Kambhampati, S. , Ramachandra, N. , Mantzaris, I. , Sukrithan, V. , Laurence, R. , Lopez, R. , Bhagat, P. , Giricz, O. , Sohal, D. & 18 others Wickrema, A., Yeung, C., Gritsman, K., Aplan, P., Hochedlinger, K., Yu, Y., Pradhan, K., Zhang, J., Greally, J. M., Mukherjee, S., Pellagatti, A., Boultwood, J., Will, B., Steidl, U., Raaijmakers, M. H. G. P., Deeg, H. J., Kharas, M. G. & Verma, A. Sep 15 2017 In : Cancer Research. 77, 18, p. 4846-4857 12 p.

Research output: Research - peer-reviewArticle

Myelodysplastic Syndromes
beta Catenin
Catenins
Bone Marrow
Methyltransferases

ETO2-GLIS2: A Chimeric Transcription Factor Drives Leukemogenesis through a Neomorphic Transcription Network

Wheat, J. C. & Steidl, U. Mar 13 2017 In : Cancer Cell. 31, 3, p. 307-308 2 p.

Research output: Research - peer-reviewShort survey

Leukemia, Megakaryoblastic, Acute
Transcription Factors
Leukemia
Neoplasms
Proteins

Pharmacological inhibition of the transcription factor PU.1 in leukemia

Antony-Debré, I. , Paul, A. , Leite, J. , Mitchell, K. , Kim, H. M. , Carvajal, L. A. , Todorova, T. I. , Huang, K. , Kumar, A. , Farahat, A. A. , Bartholdy, B. , Narayanagari, S. R. , Chen, J. , Ambesi-Impiombato, A. , Ferrando, A. A. , Mantzaris, I. , Gavathiotis, E. , Verma, A. , Will, B. , Boykin, D. W. & 3 others Wilson, W. D., Poon, G. M. K. & Steidl, U. Dec 1 2017 In : Journal of Clinical Investigation. 127, 12, p. 4297-4313 17 p.

Research output: Research - peer-reviewArticle

Acute Myeloid Leukemia
Leukemia
Pharmacology
proto-oncogene protein Spi-1
Therapeutics