Projects per year
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- 37 Similar Profiles
Acute Myeloid Leukemia
Medicine & Life Sciences
Myelodysplastic Syndromes
Medicine & Life Sciences
Hematopoietic Stem Cells
Medicine & Life Sciences
Stem Cells
Medicine & Life Sciences
Stem cells
Chemical Compounds
Leukemia
Medicine & Life Sciences
Multiple Myeloma
Medicine & Life Sciences
Epigenomics
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2008 2022
Therapeutic targeting of MDS stem cells
8/20/18 → 6/30/22
Project: Research project › Research Project
Interleukin-8
Stem Cells
Therapeutics
Heterografts
Disease Progression
Mechanisms of Formation and Progression of Preleukemic Stem Cells
4/1/17 → 3/31/22
Project: Research project › Research Project
Stem Cells
Small Interfering RNA
Leukemia
Recurrence
Critical Pathways
Role of a Novel Homeobox Transcription Factor (HLX) in Acute Myeloid Leukemia
4/1/13 → 3/31/19
Project: Research project › Research Project
Homeobox Genes
Acute Myeloid Leukemia
Transcription Factors
Leukemia
Critical Pathways
Transcriptional regulation of leukemic stem cells in acute myeloid leukemia
9/1/08 → 4/30/12
Project: Research project › Research Transition Award, Career Transition Award
Acute Myeloid Leukemia
Stem Cells
Leukemia
Transcription Factors
Maintenance
Publications 1998 2018
Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia
Carvajal, L. A., Ben Neriah, D., Senecal, A., Benard, L., Thiruthuvanathan, V., Yatsenko, T., Narayanagari, S-R., Wheat, J. C., Todorova, T. I., Mitchell, K., Kenworthy, C., Guerlavais, V., Annis, D. A., Bartholdy, B. A., Will, B., Anampa Mesias, J. D., Mantzaris, I., Aivado, M., Singer, R. H., Coleman, R. A. & 2 others, Apr 11 2018, In : Science Translational Medicine. 10, 436, aao3003.Research output: Contribution to journal › Article
Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints
Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD
Escudero, S., Zaganjor, E., Lee, S., Mill, C. P., Morgan, A. M., Crawford, E. B., Chen, J., Wales, T. E., Mourtada, R., Luccarelli, J., Bird, G. H., Steidl, U. G., Engen, J. R., Haigis, M. C., Opferman, J. T. & Walensky, L. D., Mar 1 2018, In : Molecular Cell. 69, 5, p. 802-819.e1Research output: Contribution to journal › Article
Long-Chain Acyl-CoA Dehydrogenase
Fatty Acids
Lipid Metabolism
Palmitic Acid
Human Development
Erratum to: Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level (Nature Medicine, (2018), 10.1038/s41591-018-0267-4)
Chen, J., Kao, Y. R., Sun, D., Todorova, T. I., Reynolds, D., Narayanagari, S-R., Montagna, C., Will, B., Verma, A. K. & Steidl, U. G., Jan 1 2018, (Accepted/In press) In : Nature medicine.Research output: Contribution to journal › Article
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Myelodysplastic Syndromes
Stem cells
Acute Myeloid Leukemia
Medicine
IL1RAP potentiates multiple oncogenic signaling pathways in AML
Mitchell, K., Barreyro, L., Todorova, T. I., Taylor, S. J., Antony-Debré, I., Narayanagari, S-R., Carvajal, L. A., Leite, J., Piperdi, Z., Pendurti, G., Mantzaris, I., Paietta, E. M., Verma, A. K., Gritsman, K. & Steidl, U. G., Jun 1 2018, In : Journal of Experimental Medicine. 215, 6, p. 1709-1727 19 p.Research output: Contribution to journal › Article
Interleukin-1 Receptor Accessory Protein
Acute Myeloid Leukemia
Interleukin-1 Receptors
Receptor Protein-Tyrosine Kinases
Protein Transport
Inhibition of HIF1α Signaling: A Grand Slam for MDS Therapy?
Chen, J. & Steidl, U. G., Nov 1 2018, In : Cancer discovery. 8, 11, p. 1355-1357 3 p.Research output: Contribution to journal › Article
Myelodysplastic Syndromes
Therapeutics
Genetic Heterogeneity
Hematopoiesis
Genomics