Projects per year
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- 32 Similar Profiles
Acute Myeloid Leukemia
Medicine & Life Sciences
Myelodysplastic Syndromes
Medicine & Life Sciences
Hematopoietic Stem Cells
Medicine & Life Sciences
Stem Cells
Medicine & Life Sciences
Leukemia
Medicine & Life Sciences
Stem cells
Chemical Compounds
Epigenomics
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2008 2022
Mechanisms of Formation and Progression of Preleukemic Stem Cells
4/1/17 → 3/31/22
Project: Research project › Research Project
Stem Cells
Small Interfering RNA
Leukemia
Recurrence
Critical Pathways
Role of a Novel Homeobox Transcription Factor (HLX) in Acute Myeloid Leukemia
4/1/13 → 3/31/18
Project: Research project › Research Project
Homeobox Genes
Acute Myeloid Leukemia
Transcription Factors
Leukemia
Critical Pathways
Transcriptional regulation of leukemic stem cells in acute myeloid leukemia
9/1/08 → 4/30/12
Project: Research project › Research Transition Award, Career Transition Award
Acute Myeloid Leukemia
Stem Cells
Leukemia
Transcription Factors
Maintenance
Publications 1998 2018
Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia
Carvajal, L. A. , Ben Neriah, D. , Senecal, A. , Benard, L. , Thiruthuvanathan, V. , Yatsenko, T. , Narayanagari, S. R. , Wheat, J. C. , Todorova, T. I. , Mitchell, K. , Kenworthy, C. , Guerlavais, V. , Annis, D. A. , Bartholdy, B. , Will, B. , Anampa, J. D. , Mantzaris, I. , Aivado, M. , Singer, R. H. , Coleman, R. A. & 2 others Apr 11 2018 In : Science Translational Medicine. 10, 436, aao3003Research output: Contribution to journal › Article
Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints
Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD
Escudero, S., Zaganjor, E., Lee, S., Mill, C. P., Morgan, A. M., Crawford, E. B., Chen, J., Wales, T. E., Mourtada, R., Luccarelli, J., Bird, G. H., Steidl, U., Engen, J. R., Haigis, M. C., Opferman, J. T. & Walensky, L. D. Mar 1 2018 In : Molecular Cell. 69, 5, p. 802-819.e1Research output: Contribution to journal › Article
Long-Chain Acyl-CoA Dehydrogenase
Mitochondria
Fatty Acids
Apoptosis
Lipid Metabolism
IL1RAP potentiates multiple oncogenic signaling pathways in AML
Mitchell, K., Barreyro, L., Todorova, T. I., Taylor, S. J., Antony-Debré, I., Narayanagari, S. R., Carvajal, L. A., Leite, J., Piperdi, Z., Pendurti, G., Mantzaris, I., Paietta, E., Verma, A., Gritsman, K. & Steidl, U. Jun 1 2018 In : Journal of Experimental Medicine. 215, 6, p. 1709-1727 19 p.Research output: Contribution to journal › Article
Interleukin-1 Receptor Accessory Protein
Acute Myeloid Leukemia
Interleukin-1 Receptors
Receptor Protein-Tyrosine Kinases
Protein Transport
LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPa-dependent enhancers in AML
Cusan, M., Cai, S. F., Mohammad, H., Krivtsov, A., Chramiec, A., Loizou, E., Witkin, M. D., Smitheman, K. N., Tenen, D. G., Ye, M., Will, B., Steidl, U., Kruger, R. G., Levine, R. L., Rienhoff, H. Y., Koche, R. P. & Armstrong, S. A. Apr 12 2018 In : Blood. 131, 15, p. 1730-1742 13 p.Research output: Contribution to journal › Article
Rotary engines
Efflorescence
Acute Myeloid Leukemia
Lysine
Leukemia
Macrocytosis and dysplastic anemia is associated with the cyclin-dependent kinase 4/6 inhibitor palbociclib in metastatic breast cancer
Anampa, J., Haque, T., Murakhovskaya, I., Wang, Y., Bachiashvili, K., Papazoglu, C., Pradhan, K., Steidl, U. G., Sparano, J. A. & Verma, A. Feb 28 2018 In : Haematologica. 103, 3, p. e98-e102Research output: Contribution to journal › Letter
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase 4
Anemia
Breast Neoplasms
palbociclib