• 3714 Citations
  • 37 h-Index
19982022
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  • 26 Similar Profiles
Acute Myeloid Leukemia Medicine & Life Sciences
Myelodysplastic Syndromes Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Stem cells Chemical Compounds
Multiple Myeloma Medicine & Life Sciences
Epigenomics Medicine & Life Sciences

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Grants 2008 2022

Therapeutic targeting of MDS stem cells

Verma, A. K. & Steidl, U. G.

National Institutes of Health

8/20/186/30/22

Project: Research projectResearch Project

Interleukin-8
Stem Cells
Therapeutics
Heterografts
Disease Progression
Stem Cells
Small Interfering RNA
Leukemia
Recurrence
Critical Pathways
Homeobox Genes
Acute Myeloid Leukemia
Transcription Factors
Leukemia
Critical Pathways

Transcriptional regulation of leukemic stem cells in acute myeloid leukemia

Steidl, U. G.

National Institutes of Health

9/1/084/30/12

Project: Research projectCareer Transition Award, Research Transition Award

Acute Myeloid Leukemia
Stem Cells
Leukemia
Transcription Factors
Maintenance

Publications 1998 2018

3 Citations

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Carvajal, L. A., Ben Neriah, D., Senecal, A., Benard, L., Thiruthuvanathan, V., Yatsenko, T., Narayanagari, S. R., Wheat, J. C., Todorova, T. I., Mitchell, K., Kenworthy, C., Guerlavais, V., Annis, D. A., Bartholdy, B., Will, B., Anampa, J. D., Mantzaris, I., Aivado, M., Singer, R. H., Coleman, R. A. & 2 othersVerma, A. & Steidl, U., Apr 11 2018, In : Science Translational Medicine. 10, 436, aao3003.

Research output: Contribution to journalArticle

Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints
1 Citations

Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD

Escudero, S., Zaganjor, E., Lee, S., Mill, C. P., Morgan, A. M., Crawford, E. B., Chen, J., Wales, T. E., Mourtada, R., Luccarelli, J., Bird, G. H., Steidl, U., Engen, J. R., Haigis, M. C., Opferman, J. T. & Walensky, L. D., Mar 1 2018, In : Molecular Cell. 69, 5, p. 802-819.e1

Research output: Contribution to journalArticle

Long-Chain Acyl-CoA Dehydrogenase
Fatty Acids
Lipid Metabolism
Palmitic Acid
Human Development
1 Citations

IL1RAP potentiates multiple oncogenic signaling pathways in AML

Mitchell, K., Barreyro, L., Todorova, T. I., Taylor, S. J., Antony-Debré, I., Narayanagari, S. R., Carvajal, L. A., Leite, J., Piperdi, Z., Pendurti, G., Mantzaris, I., Paietta, E., Verma, A., Gritsman, K. & Steidl, U., Jun 1 2018, In : Journal of Experimental Medicine. 215, 6, p. 1709-1727 19 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptor Accessory Protein
Acute Myeloid Leukemia
Interleukin-1 Receptors
Receptor Protein-Tyrosine Kinases
Protein Transport

Inhibition of HIF1α Signaling: A Grand Slam for MDS Therapy?

Chen, J. & Steidl, U. G., Nov 1 2018, In : Cancer discovery. 8, 11, p. 1355-1357 3 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Therapeutics
Genetic Heterogeneity
Hematopoiesis
Genomics

Linking histone methylation, transcription rates, and stem cell robustness

Wheat, J. C. & Steidl, U., Jul 3 2018, In : Haematologica. 103, 7, 1 p.

Research output: Contribution to journalEditorial

Histones
Methylation
Stem Cells