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  • 6 Similar Profiles
Proteins Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Substrates Chemical Compounds
Catalytic Domain Medicine & Life Sciences
Ligands Medicine & Life Sciences
Actins Medicine & Life Sciences
Crystal structure Chemical Compounds
T-Lymphocytes Medicine & Life Sciences

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Grants 1977 2021

Function and Mechanism of Viperin, a radical SAM antiviral protein

Almo, S. C.

National Institutes of Health

6/26/175/31/19

Project: Research projectExploratory/Developmental Grants

Cytidine Triphosphate
S-Adenosylmethionine
Antiviral Agents
Proteins
Viruses
Actins
Mechanical properties
Microfilament Proteins
Protein Subunits
Electron microscopy

Novel Strategies for the Discovery of Microbial Metabolic Pathways

Almo, S. C.

National Institutes of Health

6/15/164/30/21

Project: Research projectResearch Program Projects

Ligands
Proteins
Carrier Proteins
Metabolic Networks and Pathways
Oxygen

Novel Strategies for Precision T-cell Therapies

Almo, S. C.

National Institutes of Health

6/1/165/31/21

Project: Research projectResearch Project

T-Lymphocytes
Immunological Synapses
Cell- and Tissue-Based Therapy
Therapeutics
Biological Products

Technologies for Mapping the Extracellular Interactome

Almo, S. C.

National Institutes of Health

9/24/156/30/18

Project: Research projectResearch Project

Technology
Proteins
Membrane Proteins
Therapeutics
Automation

Publications 1988 2017

  • 12189 Citations
  • 58 h-Index
  • 337 Article
  • 2 Chapter
  • 2 Conference contribution
  • 1 Review article

A novel bifunctional transcriptional regulator of riboflavin metabolism in Archaea

Rodionova, I. A., Vetting, M. W., Li, X., Almo, S. C., Osterman, A. L. & Rodionov, D. A. Apr 20 2017 In : Nucleic Acids Research. 45, 7, p. 3785-3799 15 p.

Research output: Research - peer-reviewArticle

riboflavin kinase
Riboflavin
Archaea
Flavin Mononucleotide
Cytidine Triphosphate

Can the propensity of protein crystallization be increased by using systematic screening with metals?

Hegde, R. P., Pavithra, G. C., Dey, D., Almo, S. C., Ramakumar, S. & Ramagopal, U. A. 2017 (Accepted/In press) In : Protein Science.

Research output: Research - peer-reviewArticle

Crystallization
Screening
Metals
Proteins
Metal ions
2 Citations

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Metcalf, B. , Chuang, C. , Dufu, K. , Patel, M. P. , Silva-Garcia, A. , Johnson, C. , Lu, Q. , Partridge, J. R. , Patskovska, L. , Patskovsky, Y. , Almo, S. C. , Jacobson, M. P. , Hua, L. , Xu, Q. , Gwaltney, S. L. , Yee, C. , Harris, J. , Morgan, B. P. , James, J. , Xu, D. & 4 others Hutchaleelaha, A., Paulvannan, K., Oksenberg, D. & Li, Z. Mar 9 2017 In : ACS Medicinal Chemistry Letters. 8, 3, p. 321-326 6 p.

Research output: Research - peer-reviewArticle

Sickle Hemoglobin
Hemoglobins
Erythrocytes
Stoichiometry
Blood
1 Citations

Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex

Upla, P., Kim, S. J., Sampathkumar, P., Dutta, K., Cahill, S. M., Chemmama, I. E., Williams, R., Bonanno, J. B., Rice, W. J., Stokes, D. L., Cowburn, D., Almo, S. C., Sali, A., Rout, M. P. & Fernandez-Martinez, J. Mar 7 2017 In : Structure. 25, 3, p. 434-445 12 p.

Research output: Research - peer-reviewArticle

Nuclear Pore
Membranes
Yeasts
Nuclear Envelope
Cadherins

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth

Glass, L. N., Swapna, G., Chavadi, S. S., Tufariello, J. A. M., Mi, K., Drumm, J. E., Lam, T. K. T., Zhu, G., Zhan, C., Vilchéze, C., Arcos, J., Chen, Y., Bi, L., Mehta, S., Porcelli, S. A., Almo, S. C., Yeh, S. R., Jacobs, W. R., Torrelles, J. B. & Chan, J. Jul 1 2017 In : PLoS Pathogens. 13, 7, e1006515

Research output: Research - peer-reviewArticle

ATP-Binding Cassette Transporters
Heat-Shock Proteins
Mycobacterium tuberculosis
Growth
phosphatidylinositol mannoside