Projects per year
Fingerprint Dive into the research topics where Steven C. Almo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Catalytic Domain
Medicine & Life Sciences
Actins
Medicine & Life Sciences
Enzymes
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Profilins
Medicine & Life Sciences
Substrates
Chemical Compounds
Purine-Nucleoside Phosphorylase
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 1977 2024
Novel Biologics Designed to Mobilize HIV-specific CTL for Sustained HIV Remission
4/5/19 → 3/31/24
Project: Research project
Biological Products
HIV
T-Lymphocytes
Cytokines
Viremia
An immunotherapeutic strategy for the induction and stabilization of remission in type 1 diabetes
Almo, S. C. & DiLorenzo, T. P.
9/15/18 → 7/31/21
Project: Research project
Remission Induction
Type 1 Diabetes Mellitus
T-Lymphocytes
Antigens
Immunological Synapses
Structural, functional, and mechanistic anlaysis of autoreactive CD8 T cells
Almo, S. C. & DiLorenzo, T. P.
2/8/18 → 1/31/23
Project: Research project
T-Lymphocytes
Alleles
T-Cell Antigen Receptor
Type 1 Diabetes Mellitus
Peptides
Structural basis of allostery and mechanical properties of F-actin
8/1/16 → 7/31/20
Project: Research project
Actins
Mechanical properties
Microfilament Proteins
Protein Subunits
Electron microscopy
Novel Strategies for the Discovery of Microbial Metabolic Pathways
6/15/16 → 4/30/21
Project: Research project
Carrier Proteins
Ligands
Proteins
Metabolic Networks and Pathways
Microbiota
Publications 1988 2019
Computational Redesign of PD-1 Interface for PD-L1 Ligand Selectivity
Shrestha, R., Garrett, S. C., Almo, S. C. & Fiser, A., May 7 2019, In : Structure. 27, 5, p. 829-836.e3Research output: Contribution to journal › Article
Cell Death
Ligands
Programmed Cell Death 1 Receptor
T-Lymphocytes
Human Engineering
1
Citation
(Scopus)
Genetically modified hematopoietic stem/progenitor cells that produce IL-10–secreting regulatory T cells
Ng, S. L., Leno-Duran, E., Samanta, D., Almo, S. C. & Strominger, J. L., Feb 12 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 7, p. 2634-2639 6 p.Research output: Contribution to journal › Article
Regulatory T-Lymphocytes
Hematopoietic Stem Cells
Autoimmune Experimental Encephalomyelitis
T-Cell Antigen Receptor
Interleukin-10
2
Citations
(Scopus)
GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells
Smith, E. L., Harrington, K., Staehr, M., Masakayan, R., Jones, J., Long, T. J., Ng, K. Y., Ghoddusi, M., Purdon, T. J., Wang, X., Do, T., Pham, M. T., Brown, J. M., De Larrea, C. F., Olson, E., Peguero, E., Wang, P., Liu, H., Xu, Y., Garrett-Thomson, S. C. & 6 others, , Jan 1 2019, In : Science Translational Medicine. 11, 485, eaau7746.Research output: Contribution to journal › Article
B-Cell Maturation Antigen
G-Protein-Coupled Receptors
T-Cell Antigen Receptor
Multiple Myeloma
Immunotherapy
5
Citations
(Scopus)
Novel Metabolic Pathways and Regulons for Hexuronate Utilization in Proteobacteria
Bouvier, J. T., Sernova, N. V., Ghasempur, S., Rodionova, I. A., Vetting, M. W., Al-Obaidi, N. F., Almo, S. C., Gerlt, J. A. & Rodionov, D. A., Jan 15 2019, In : Journal of Bacteriology. 201, 2Research output: Contribution to journal › Article
Regulon
Proteobacteria
Metabolic Networks and Pathways
Ralstonia pickettii
Enzymes
Structural Basis of CD160:HVEM Recognition
Liu, W., Garrett, S. C., Fedorov, E. V., Ramagopal, U. A., Garforth, S. J., Bonanno, J. B. & Almo, S. C., Aug 6 2019, In : Structure. 27, 8, p. 1286-1295.e4Research output: Contribution to journal › Article
Open Access
Virus Internalization
Mediator Complex
Mucosal Immunity
Simplexvirus
Natural Killer Cells