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Steven C. Almo, Ph.D.

  • 13724 Citations
  • 62 h-Index
1977 …2023
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Grants 1977 2023

An immunotherapeutic strategy for the induction and stabilization of remission in type 1 diabetes

Almo, S. C. & DiLorenzo, T. P.

National Institutes of Health

9/15/18 → 7/31/21

Project: Research project › Research Project

Remission Induction
Type 1 Diabetes Mellitus
T-Lymphocytes
Antigens
Immunological Synapses

Structural, functional, and mechanistic anlaysis of autoreactive CD8 T cells

Almo, S. C. & DiLorenzo, T. P.

National Institutes of Health

2/8/18 → 1/31/23

Project: Research project › Research Project

T-Lymphocytes
Alleles
T-Cell Antigen Receptor
Type 1 Diabetes Mellitus
Peptides

Function and Mechanism of Viperin, a radical SAM antiviral protein

Almo, S. C.

National Institutes of Health

6/26/17 → 5/31/19

Project: Research project › Exploratory/Developmental Grants

Cytidine Triphosphate
S-Adenosylmethionine
Antiviral Agents
Viruses
Proteins

Structural basis of allostery and mechanical properties of F-actin

Almo, S. C.

National Institutes of Health

8/1/16 → 7/31/20

Project: Research project › Research Project

Actins
Mechanical properties
Microfilament Proteins
Protein Subunits
Electron microscopy

Novel Strategies for the Discovery of Microbial Metabolic Pathways

Almo, S. C.

6/15/16 → 4/30/21

Project: Research project › Research Program Projects

Carrier Proteins
Ligands
Proteins
Metabolic Networks and Pathways
Microbiota

Publications 1988 2018

Advantages of Molecular Weight Identification during Native MS Screening

Khan, A., Bresnick, A., Cahill, S., Girvin, M., Almo, S. & Quinn, R., May 9 2018, (Accepted/In press) In : Planta Medica.

Research output: Contribution to journal › Article

Screening
Molecular Weight
Molecular weight
Mass spectrometry
Ligands
2 Citations

A herpes simplex virus (HSV)-2 single-cycle candidate vaccine deleted in glycoprotein D protects male mice from lethal skin challenge with clinical isolates of HSV-1 and HSV-2

Burn, C., Ramsey, N., Garforth, S. J., Almo, S., Jacobs, W. R. & Herold, B. C., Mar 1 2018, In : Journal of Infectious Diseases. 217, 5, p. 754-758 5 p.

Research output: Contribution to journal › Article

Human Herpesvirus 2
Human Herpesvirus 1
Glycoproteins
Vaccines
Skin
6 Citations

A naturally occurring antiviral ribonucleotide encoded by the human genome

Gizzi, A. S., Grove, T. L., Arnold, J. J., Jose, J., Jangra, R. K., Garforth, S. J., Du, Q., Cahill, S. M., Dulyaninova, N. G., Love, J. D., Chandran, K., Bresnick, A. R., Cameron, C. E. & Almo, S. C., Jun 28 2018, In : Nature. 558, 7711, p. 610-614 5 p.

Research output: Contribution to journal › Article

Ribonucleotides
Cytidine Triphosphate
Human Genome
Antiviral Agents
Methionine
2 Citations

Anti-CTLA-4 therapy requires an Fc domain for efficacy

Ingram, J. R., Blomberg, O. S., Rashidian, M., Ali, L., Garforth, S., Fedorov, E., Fedorov, A. A., Bonanno, J. B., Le Gall, C., Crowley, S., Espinosa, C., Biary, T., Keliher, E. J., Weissleder, R., Almo, S. C., Dougan, S. K., Ploegh, H. L. & Dougan, M., Jan 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 15, p. 3912-3917 6 p.

Research output: Contribution to journal › Article

CTLA-4 Antigen
Therapeutics
Thomsen-Friedenreich antibodies
Antibodies
New World Camelids

Comparison of Alicyclobacillus acidocaldarius OSBS to its promiscuous NSAR/OSBS relatives

Odokonyero, D., McMillan, A. W., Ramagopal, U. A., Toro, R., Truong, D. P., Zhu, M., Lopez, M. S., Somiari, B., Herman, M., Aziz, A., Bonanno, J. B., Hull, K. G., Burley, S. K., Romo, D., Almo, S. C. & Glasner, M. E., Jan 26 2018, (Accepted/In press) In : Biochemistry.

Research output: Contribution to journal › Article

Alicyclobacillus
Racemases and Epimerases
Acids
Enzymes
Molecular modeling