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  • 21 Similar Profiles
Proteins Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Actins Medicine & Life Sciences
Ligands Medicine & Life Sciences
Substrates Chemical Compounds
Phosphates Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences

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Grants 1977 2021

Function and Mechanism of Viperin, a radical SAM antiviral protein

Almo, S. C.

National Institutes of Health

6/26/175/31/19

Project: Research projectExploratory/Developmental Grants

Cytidine Triphosphate
S-Adenosylmethionine
Antiviral Agents
Proteins
Viruses
Actins
Microfilament Proteins
Protein Subunits
Cryoelectron Microscopy
Actin Cytoskeleton

Novel Strategies for the Discovery of Microbial Metabolic Pathways

Almo, S. C.

National Institutes of Health

6/15/164/30/21

Project: Research projectResearch Program Projects

Ligands
Proteins
Carrier Proteins
Metabolic Networks and Pathways
Oxygen

Novel Strategies for Precision T-cell Therapies

Almo, S. C.

National Institutes of Health

6/1/165/31/21

Project: Research projectResearch Project

T-Lymphocytes
Immunological Synapses
Cell- and Tissue-Based Therapy
Biological Products
Peptides

Technologies for Mapping the Extracellular Interactome

Almo, S. C.

National Institutes of Health

9/24/156/30/18

Project: Research projectResearch Project

Technology
Proteins
Membrane Proteins
Automation
Proteome

Publications 1988 2017

  • 11975 Citations
  • 58 h-Index
  • 334 Article
  • 2 Chapter
  • 2 Conference contribution
  • 1 Review article

A novel bifunctional transcriptional regulator of riboflavin metabolism in Archaea

Rodionova, I. A., Vetting, M. W., Li, X., Almo, S. C., Osterman, A. L. & Rodionov, D. A. Apr 20 2017 In : Nucleic Acids Research. 45, 7, p. 3785-3799 15 p.

Research output: Contribution to journalArticle

Riboflavin
Archaea
Phosphotransferases
Flavin Mononucleotide
Cytidine Triphosphate

Can the propensity of protein crystallization be increased by using systematic screening with metals?

Hegde, R. P., Pavithra, G. C., Dey, D., Almo, S. C., Ramakumar, S. & Ramagopal, U. A. 2017 In : Protein Science.

Research output: Contribution to journalArticle

Crystallization
Metals
Proteins
Ions
Kernicterus
1 Citations

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Metcalf, B. , Chuang, C. , Dufu, K. , Patel, M. P. , Silva-Garcia, A. , Johnson, C. , Lu, Q. , Partridge, J. R. , Patskovska, L. , Patskovsky, Y. , Almo, S. C. , Jacobson, M. P. , Hua, L. , Xu, Q. , Gwaltney, S. L. , Yee, C. , Harris, J. , Morgan, B. P. , James, J. , Xu, D. & 4 others Hutchaleelaha, A., Paulvannan, K., Oksenberg, D. & Li, Z. Mar 9 2017 In : ACS Medicinal Chemistry Letters. 8, 3, p. 321-326 6 p.

Research output: Contribution to journalArticle

Sickle Hemoglobin
Hemoglobins
Erythrocytes
Phase III Clinical Trials
Sickle Cell Anemia

Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex

Upla, P., Kim, S. J., Sampathkumar, P., Dutta, K., Cahill, S. M., Chemmama, I. E., Williams, R., Bonanno, J. B., Rice, W. J., Stokes, D. L., Cowburn, D., Almo, S. C., Sali, A., Rout, M. P. & Fernandez-Martinez, J. Mar 7 2017 In : Structure. 25, 3, p. 434-445 12 p.

Research output: Contribution to journalArticle

Nuclear Pore
Membranes
Yeasts
Nuclear Envelope
Cadherins

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth

Glass, L. N., Swapna, G., Chavadi, S. S., Tufariello, J. A. M., Mi, K., Drumm, J. E., Lam, T. K. T., Zhu, G., Zhan, C., Vilchéze, C., Arcos, J., Chen, Y., Bi, L., Mehta, S., Porcelli, S. A., Almo, S. C., Yeh, S. R., Jacobs, W. R., Torrelles, J. B. & Chan, J. Jul 1 2017 In : PLoS Pathogens. 13, 7, e1006515

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Heat-Shock Proteins
Mycobacterium tuberculosis
Mannosides
Phosphatidylinositols