• 15114 Citations
  • 66 h-Index
1977 …2024
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Fingerprint Dive into the research topics where Steven C. Almo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Catalytic Domain Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Actins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Ligands Medicine & Life Sciences
Profilins Medicine & Life Sciences
Substrates Chemical Compounds
Purine-Nucleoside Phosphorylase Medicine & Life Sciences

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Grants 1977 2024

Biological Products
HIV
T-Lymphocytes
Cytokines
Viremia
Remission Induction
Type 1 Diabetes Mellitus
T-Lymphocytes
Antigens
Immunological Synapses
T-Lymphocytes
Alleles
T-Cell Antigen Receptor
Type 1 Diabetes Mellitus
Peptides
Actins
Mechanical properties
Microfilament Proteins
Protein Subunits
Electron microscopy
Carrier Proteins
Ligands
Proteins
Metabolic Networks and Pathways
Microbiota

Publications 1988 2019

2 Citations (Scopus)

An essential bifunctional enzyme in Mycobacterium tuberculosis for itaconate dissimilation and leucine catabolism

Wang, H., Fedorov, A. A., Fedorov, E. V., Hunt, D. M., Rodgers, A., Douglas, H. L., Garza-Garcia, A., Bonanno, J. B., Almo, S. C. & de Carvalho, L. P. S., Aug 6 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 32, p. 15907-15913 7 p.

Research output: Contribution to journalArticle

Open Access
Mycobacterium tuberculosis
Leucine
Enzymes
Mycobacterium Infections
Lyases

Computational Redesign of PD-1 Interface for PD-L1 Ligand Selectivity

Shrestha, R., Garrett, S. C., Almo, S. C. & Fiser, A., May 7 2019, In : Structure. 27, 5, p. 829-836.e3

Research output: Contribution to journalArticle

Cell Death
Ligands
Programmed Cell Death 1 Receptor
T-Lymphocytes
Human Engineering

Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens

Yuan, Y., Zallot, R., Grove, T. L., Payan, D. J., Martin-Verstraete, I., Šepić, S., Balamkundu, S., Neelakandan, R., Gadi, V. K., Liu, C. F., Swairjo, M. A., Dedon, P. C., Almo, S. C., Gerlt, J. A. & de Crécy-Lagard, V., Sep 17 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 38, p. 19126-19135 10 p.

Research output: Contribution to journalArticle

Open Access
Bacteria
queuine tRNA-ribosyltransferase
Enzymes
Eukaryota
Nucleoside Q
1 Citation (Scopus)

Genetically modified hematopoietic stem/progenitor cells that produce IL-10–secreting regulatory T cells

Ng, S. L., Leno-Duran, E., Samanta, D., Almo, S. C. & Strominger, J. L., Feb 12 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 7, p. 2634-2639 6 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Hematopoietic Stem Cells
Autoimmune Experimental Encephalomyelitis
T-Cell Antigen Receptor
Interleukin-10
5 Citations (Scopus)

GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells

Smith, E. L., Harrington, K., Staehr, M., Masakayan, R., Jones, J., Long, T. J., Ng, K. Y., Ghoddusi, M., Purdon, T. J., Wang, X., Do, T., Pham, M. T., Brown, J. M., De Larrea, C. F., Olson, E., Peguero, E., Wang, P., Liu, H., Xu, Y., Garrett-Thomson, S. C. & 6 others, Almo, S. C., Wendel, H. G., Riviere, I., Liu, C., Sather, B. & Brentjens, R. J., Jan 1 2019, In : Science Translational Medicine. 11, 485, eaau7746.

Research output: Contribution to journalArticle

B-Cell Maturation Antigen
G-Protein-Coupled Receptors
T-Cell Antigen Receptor
Multiple Myeloma
Immunotherapy