Steven C. Almo, Ph.D.

Rodionova, I. A., Vetting, M. W., Li, X., Almo, S. C., Osterman, A. L. & Rodionov, D. A. Apr 20 2017 In : Nucleic Acids Research. 45, 7, p. 3785-3799 15 p.

Research output: Contribution to journal › Article

Riboflavin

Archaea

Phosphotransferases

Flavin Mononucleotide

Cytidine Triphosphate

Can the propensity of protein crystallization be increased by using systematic screening with metals?

Hegde, R. P., Pavithra, G. C., Dey, D., Almo, S. C., Ramakumar, S. & Ramagopal, U. A. 2017 In : Protein Science.

Research output: Contribution to journal › Article

Crystallization

Metals

Proteins

Ions

Kernicterus

1 Citations

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Metcalf, B. , Chuang, C. , Dufu, K. , Patel, M. P. , Silva-Garcia, A. , Johnson, C. , Lu, Q. , Partridge, J. R. , Patskovska, L. , Patskovsky, Y. , Almo, S. C. , Jacobson, M. P. , Hua, L. , Xu, Q. , Gwaltney, S. L. , Yee, C. , Harris, J. , Morgan, B. P. , James, J. , Xu, D. & 4 others Hutchaleelaha, A., Paulvannan, K., Oksenberg, D. & Li, Z. Mar 9 2017 In : ACS Medicinal Chemistry Letters. 8, 3, p. 321-326 6 p.

Research output: Contribution to journal › Article

Sickle Hemoglobin

Hemoglobins

Erythrocytes

Phase III Clinical Trials

Sickle Cell Anemia

Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex

Upla, P., Kim, S. J., Sampathkumar, P., Dutta, K., Cahill, S. M., Chemmama, I. E., Williams, R., Bonanno, J. B., Rice, W. J., Stokes, D. L., Cowburn, D., Almo, S. C., Sali, A., Rout, M. P. & Fernandez-Martinez, J. Mar 7 2017 In : Structure. 25, 3, p. 434-445 12 p.

Research output: Contribution to journal › Article

Nuclear Pore

Membranes

Yeasts

Nuclear Envelope

Cadherins

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth

Glass, L. N., Swapna, G., Chavadi, S. S., Tufariello, J. A. M., Mi, K., Drumm, J. E., Lam, T. K. T., Zhu, G., Zhan, C., Vilchéze, C., Arcos, J., Chen, Y., Bi, L., Mehta, S., Porcelli, S. A., Almo, S. C., Yeh, S. R., Jacobs, W. R., Torrelles, J. B. & Chan, J. Jul 1 2017 In : PLoS Pathogens. 13, 7, e1006515

Research output: Contribution to journal › Article

ATP-Binding Cassette Transporters

Heat-Shock Proteins

Mycobacterium tuberculosis

Mannosides

Phosphatidylinositols