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Robert H. Singer, Ph.D.

  • 26280 Citations
  • 94 h-Index
1963 …2022
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Messenger RNA Medicine & Life Sciences
Actins Medicine & Life Sciences
RNA Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cells Chemical Compounds
Gene Expression Medicine & Life Sciences
In Situ Hybridization Medicine & Life Sciences
Transcription Chemical Compounds

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Grants 1984 2022

Tools For Imaging the Functional Genome in Living Cells and Tissues

Singer, R. H. & Darzacq, X.

National Institutes of Health

9/30/15 → 6/30/20

Project: Research project

Financial Management
Genome
Phototoxic Dermatitis
Technology
Chromosome Mapping

Tools For Imaging the Functional Genome in Living Cells and Tissues

Singer, R. H.

National Institutes of Health

9/30/15 → 6/30/20

Project: Research project

genome
Financial Management
microscopes
Genome
Phototoxic Dermatitis

RNA TRANSPORT AND LOCALIZATION IN YEAST IN SITU

Singer, R. H.

National Institutes of Health

1/1/98 → 11/30/19

Project: Research project

RNA Transport
Yeasts
Messenger RNA
Parturition
Cell Nucleus Active Transport

Mechanism of Actin mRNA Localization and Localized Translation in Neurons

Singer, R. H.

National Institutes of Health

3/3/92 → 8/31/22

Project: Research project

Neurons
Actins
Messenger RNA
Proteins
Synapses

Imaging Transcription in Living Animals

Singer, R. H.

National Institutes of Health

4/1/12 → 1/31/17

Project: Research project

Genes
Actins
Photons
Gene Expression
Capsid Proteins

Publications 1963 2019

Bidirectional analysis of cryba4-crybb1 nascent transcription and nuclear accumulation of crybb3 mrnas in lens fibers

Limi, S., Zhao, Y., Guo, P., Lopez-Jones, M., Zheng, D., Singer, R. H., Skoultchi, A. I. & Cvekl, A., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 1, p. 234-244 11 p.

Research output: Contribution to journal › Article

Lenses
Genes
Cell Nucleus
Crystallins
Alleles

The travels of mRNAs in neurons: do they know where they are going?

Das, S., Singer, R. H. & Yoon, Y. J., Aug 1 2019, In : Current Opinion in Neurobiology. 57, p. 110-116 7 p.

Research output: Contribution to journal › Review article

Neurons
Messenger RNA
Dendrites
Axons
RNA
30 Citations (Scopus)

An improved MS2 system for accurate reporting of the mRNA life cycle

Tutucci, E., Vera Ugalde, M., Biswas, J., Garcia, J., Parker, R. & Singer, R. H., Jan 3 2018, In : Nature Methods. 15, 1, p. 81-89 9 p.

Research output: Contribution to journal › Article

Life Cycle Stages
Life cycle
Messenger RNA
Capsid Proteins
RNA Stability
6 Citations (Scopus)

A transgenic mouse for imaging activity-dependent dynamics of endogenous arc mRNA in live neurons

Das, S., Moon, H. C., Singer, R. H. & Park, H. Y., Jun 20 2018, In : Science advances. 4, 6, eaar3448.

Research output: Contribution to journal › Article

Transgenic Mice
Neurons
Messenger RNA
Neuronal Plasticity
Gene Expression Regulation
11 Citations (Scopus)

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Carvajal, L. A., Ben Neriah, D., Senecal, A., Benard, L., Thiruthuvanathan, V., Yatsenko, T., Narayanagari, S-R., Wheat, J. C., Todorova, T. I., Mitchell, K., Kenworthy, C., Guerlavais, V., Annis, D. A., Bartholdy, B. A., Will, B., Anampa Mesias, J. D., Mantzaris, I., Aivado, M., Singer, R. H., Coleman, R. A. & 2 othersVerma, A. K. & Steidl, U. G., Apr 11 2018, In : Science Translational Medicine. 10, 436, aao3003.

Research output: Contribution to journal › Article

Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints