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Robert A. Coleman, Ph.D.

  • 550 Citations
  • 11 h-Index
1995 …2022
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  • 10 Similar Profiles
TATA-Box Binding Protein Medicine & Life Sciences
Transcription Factor TFIID Medicine & Life Sciences
DNA Medicine & Life Sciences
Transcription Factor TFIIA Medicine & Life Sciences
RNA Polymerase II Medicine & Life Sciences
Transcription Chemical Compounds
Cryoelectron Microscopy Medicine & Life Sciences
Dimerization Medicine & Life Sciences

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Grants 2018 2022

Dissecting the dynamic interplay between p53, chromatin and transcriptional bursting in single cells

Coleman, R. A.

National Institutes of Health

4/1/18 → 3/31/22

Project: Research project

Chromatin
DNA Polymerase II
Histones
Histone Acetyltransferases
Transcription Factors

Publications 1995 2018

  • 550 Citations
  • 11 h-Index
  • 13 Article
  • 1 Conference contribution
  • 1 Review article

A new era of studying p53-mediated transcription activation

Liu, W. L., Coleman, R. A. & Singh, S. K., Mar 15 2018, In : Transcription. 9, 2, p. 102-107 6 p.

Research output: Contribution to journal › Review article

Cryoelectron Microscopy
RNA Polymerase II
Transcription
Transcriptional Activation
Carcinogenesis
23 Citations (Scopus)

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Carvajal, L. A., Ben Neriah, D., Senecal, A., Benard, L., Thiruthuvanathan, V., Yatsenko, T., Narayanagari, S. R., Wheat, J. C., Todorova, T. I., Mitchell, K., Kenworthy, C., Guerlavais, V., Annis, D. A., Bartholdy, B., Will, B., Anampa, J. D., Mantzaris, I., Aivado, M., Singer, R. H., Coleman, R. A. & 2 others, Verma, A. & Steidl, U., Apr 11 2018, In : Science Translational Medicine. 10, 436, aao3003.

Research output: Contribution to journal › Article

Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints
4 Citations (Scopus)

Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process

Limi, S., Senecal, A., Coleman, R. A., Lopez-Jones, M., Guo, P., Polumbo, C., Singer, R. H., Skoultchi, A. I. & Cvekl, A., Jan 1 2018, In : Journal of Biological Chemistry. 293, 34, p. 13176-13190 15 p.

Research output: Contribution to journal › Article

Lenses
Cell Differentiation
Fibers
Genes
Chromatin
5 Citations (Scopus)

p53 dynamically directs TFIID assembly on target gene promoters

Coleman, R. A., Qiao, Z., Singh, S. K., Peng, C. S., Cianfrocco, M., Zhang, Z., Piasecka, A., Aldeborgh, H., Basishvili, G. & Liu, W. L., Jul 1 2017, In : Molecular and Cellular Biology. 37, 13, e00085-17.

Research output: Contribution to journal › Article

Transcription Factor TFIID
Genes
DNA
Nucleic Acid Conformation
Cryoelectron Microscopy
22 Citations (Scopus)

Imaging transcription: Past, present, and future

Coleman, R. A., Liu, Z., Darzacq, X., Tjian, R., Singer, O. H. & Lionnet, T., 2016, 21st Century Genetics Genes at Work, 2015. Cold Spring Harbor Laboratory Press, Vol. 80. p. 1-8 8 p. (Cold Spring Harbor Symposia on Quantitative Biology; vol. 80).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Transcription
Technology
Imaging techniques
Biochemical Phenomena
Stochastic Processes