• 4646 Citations
  • 27 h-Index
1981 …2019

Research output per year

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Publications

  • 4646 Citations
  • 27 h-Index
  • 36 Article
  • 1 Comment/debate
  • 1 Review article
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Article
2019

P21CIP1 promotes mammary cancer-initiating cells via activation of Wnt/TCF1/CyclinD1 signaling

Benard, O., Qian, X., Liang, H., Ren, Z., Suyama, K., Norton, L. & Hazan, R. B., Jul 1 2019, In : Molecular Cancer Research. 17, 7, p. 1571-1581 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

An Akt3 splice variant lacking the serine 472 phosphorylation site promotes apoptosis and suppresses mammary tumorigenesis

Suyama, K., Yao, J., Liang, H., Benard, O., Loudig, O. D., Amgalan, D., McKimpson, W. M., Phillips, G. R., Segall, J., Wang, Y., Fineberg, S., Norton, L., Kitsis, R. N. & Hazan, R. B., Jan 1 2018, In : Cancer research. 78, 1, p. 103-114 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2015

Tracking surface glycans on live cancer cells with single-molecule sensitivity

Jiang, H., English, B. P., Hazan, R. B., Wu, P. & Ovryn, B., Feb 9 2015, In : Angewandte Chemie - International Edition. 54, 6, p. 1765-1769 5 p.

Research output: Contribution to journalArticle

44 Scopus citations
2014

N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties

Qian, X., Anzovino, A., Kim, S., Suyama, K., Yao, J., Hulit, J., Agiostratidou, G., Chandiramani, N., McDaid, H. M., Nagi, C., Cohen, H. W., Phillips, G. R., Norton, L. & Hazan, R. B., Jun 26 2014, In : Oncogene. 33, 26, p. 3411-3421 11 p.

Research output: Contribution to journalArticle

71 Scopus citations

Slug promotes survival during metastasis through suppression of puma-mediated apoptosis

Kim, S., Yao, J., Suyama, K., Qian, X., Qian, B. Z., Bandyopadhyay, S., Loudig, O., De Leon-Rodriguez, C., Zhou, Z. N., Segall, J., Macian, F., Norton, L. & Hazan, R. B., Jul 15 2014, In : Cancer Research. 74, 14, p. 3695-3706 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
2013

Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma

Hou, J. Y., Rodriguez-Gabin, A., Samaweera, L., Hazan, R., Goldberg, G. L., Horwitz, S. B. & McDaid, H. M., Feb 4 2013, In : PloS one. 8, 2, e54103.

Research output: Contribution to journalArticle

18 Scopus citations

N-cadherin regulates mammary tumor cell migration through Akt3 suppression

Chung, S., Yao, J., Suyama, K., Bajaj, S., Qian, X., Loudig, O. D., Eugenin, E. A., Phillips, G. R. & Hazan, R. B., Jan 24 2013, In : Oncogene. 32, 4, p. 422-430 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

P21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis

Qian, X., Hulit, J., Suyama, K., Eugenin, E. A., Belbin, T. J., Loudig, O., Smirnova, T., Zhou, Z. N., Segall, J., Locker, J., Phillips, G. R., Norton, L. & Hazan, R. B., May 2 2013, In : Oncogene. 32, 18, p. 2292-2303 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
2012

Effective DNA/RNA co-extraction for analysis of microRNAs, mRNAs, and genomic DNA from formalin-fixed paraffin-embedded specimens

Kotorashvili, A., Ramnauth, A., Liu, C., Lin, J., Ye, K., Kim, R., Hazan, R., Rohan, T., Fineberg, S. & Loudig, O., Apr 13 2012, In : PloS one. 7, 4, e34683.

Research output: Contribution to journalArticle

44 Scopus citations
2010

LC3-dependent intracellular membrane tubules induced by γ-protocadherins A3 and B2: A role for intraluminal interactions

Hanson, H. H., Kang, S., Fernández-Monreal, M., Oung, T., Yildirim, M., Lee, R., Suyama, K., Hazan, R. B. & Phillips, G. R., Jul 2 2010, In : Journal of Biological Chemistry. 285, 27, p. 20982-20992 11 p.

Research output: Contribution to journalArticle

24 Scopus citations
2009

Loss of retinal cadherin facilitates mammary tumor progression and metastasis

Agiostratidou, G., Li, M., Suyama, K., Badano, I., Keren, R., Chung, S., Anzovino, A., Hulit, J., Qian, B., Bouzahzah, B., Eugenin, E., Loudig, O., Phillips, G. R., Locker, J. & Hazan, R. B., Jun 15 2009, In : Cancer research. 69, 12, p. 5030-5038 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Profilin-1 overexpression restores adherens junctions in MDA-MB-231 breast cancer cells in R-cadherin-dependent manner

Zou, L., Hazan, R. & Roy, P., Dec 2009, In : Cell motility and the cytoskeleton. 66, 12, p. 1048-1056 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
2007

Differential cadherin expression: Potential markers for epithelial to mesenchymal transformation during tumor progression

Agiostratidou, G., Hulit, J., Phillips, G. R. & Hazan, R. B., Sep 1 2007, In : Journal of Mammary Gland Biology and Neoplasia. 12, 2-3, p. 127-133 7 p.

Research output: Contribution to journalArticle

73 Scopus citations

N-cadherin signaling potentiates mammary tumor metastasis via enhanced extracellular signal-regulated kinase activation

Hulit, J., Suyama, K., Chung, S., Keren, R., Agiostratidou, G., Shan, W., Dong, X., Williams, T. M., Lisanti, M. P., Knudsen, K. & Hazan, R. B., Apr 1 2007, In : Cancer research. 67, 7, p. 3106-3116 11 p.

Research output: Contribution to journalArticle

145 Scopus citations
2006

Heparanase promotes growth, angiogenesis and survival of primary breast tumors

Cohen, I., Pappo, O., Elkin, M., San, T., Bar-Shavit, R., Hazan, R., Peretz, T., Vlodavsky, I. & Abramovitch, R., Apr 1 2006, In : International Journal of Cancer. 118, 7, p. 1609-1617 9 p.

Research output: Contribution to journalArticle

118 Scopus citations
2005

Cadherins and catenins in clival chordomas: Correlation of expression with tumor aggressiveness

Triana, A., Sen, C., Wolfe, D. & Hazan, R., Nov 1 2005, In : American Journal of Surgical Pathology. 29, 11, p. 1422-1434 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

N-cadherin expression in breast cancer: Correlation with an aggressive histologic variant - Invasive micropapillary carcinoma

Nagi, C., Guttman, M., Jaffer, S., Qiao, R., Keren, R., Triana, A., Li, M., Godbold, J., Bleiweiss, I. J. & Hazan, R. B., Dec 1 2005, In : Breast Cancer Research and Treatment. 94, 3, p. 225-235 11 p.

Research output: Contribution to journalArticle

67 Scopus citations
2004

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo: Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion

Williams, T. M., Medina, F., Badano, I., Hazan, R. B., Hutchinson, J., Muller, W. J., Chopra, N. G., Scherer, P. E., Pestell, R. G. & Lisanti, M. P., Dec 3 2004, In : Journal of Biological Chemistry. 279, 49, p. 51630-51646 17 p.

Research output: Contribution to journalArticle

253 Scopus citations
2002

A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

Suyama, K., Shapiro, I., Guttman, M. & Hazan, R. B., Oct 2002, In : Cancer Cell. 2, 4, p. 301-314 14 p.

Research output: Contribution to journalArticle

386 Scopus citations
2000

Basement membrane alterations in psoriasis are accompanied by epidermal overexpression of MMP-2 and its inhibitor TIMP-2

Fleischmajer, R., Kuroda, K., Hazan, R., Gordon, R. E., Lebwohl, M. G., Sapadin, A. N., Unda, F., Iehara, N. & Yamada, Y., Jan 1 2000, In : Journal of Investigative Dermatology. 115, 5, p. 771-777 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis

Hazan, R. B., Phillips, G. R., Qiao, R. F., Norton, L. & Aaronson, S. A., Feb 21 2000, In : Journal of Cell Biology. 148, 4, p. 779-790 12 p.

Research output: Contribution to journalArticle

692 Scopus citations
1998

The epidermal growth factor receptor modulates the interaction of E- cadherin with the actin cytoskeleton

Hazan, R. B. & Norton, L., Apr 10 1998, In : Journal of Biological Chemistry. 273, 15, p. 9078-9084 7 p.

Research output: Contribution to journalArticle

208 Scopus citations
1997

N-Cadherin Promotes Adhesion between Invasive Breast Cancer Cells and the Stroma

Hazan, R. B., Kang, L., Whooley, B. P. & Borgen, P. I., 1997, In : Cell Communication and Adhesion. 4, 6, p. 399-411 13 p.

Research output: Contribution to journalArticle

Open Access
175 Scopus citations

Vinculin is associated with the E-cadherin adhesion complex

Hazan, R. B., Kang, L., Roe, S., Borgen, P. I. & Rimm, D. L., Dec 19 1997, In : Journal of Biological Chemistry. 272, 51, p. 32448-32453 6 p.

Research output: Contribution to journalArticle

122 Scopus citations
1995

EGF receptor‐mediated signals are differentially modulated by concanavalin A

Hazan, R., Krushel, L. & Crossin, K. L., Jan 1995, In : Journal of Cellular Physiology. 162, 1, p. 74-85 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Functional analysis of posttranslational cleavage products of the neuron- glia cell adhesion molecule, Ng-CAM

Burgoon, M. P., Hazan, R. B., Phillips, G. R., Crossin, K. L., Edelman, G. M. & Cunningham, B. A., 1995, In : Journal of Cell Biology. 130, 3, p. 733-744 12 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
1991

Epidermal Growth Factor (EGF) Stimulates Association and Kinase Activity of Raf-1 with the EGF Receptor

App, H., Hazan, R., Zilberstein, A., Ullrich, A., Schlessinger, J. & Rapp, U., Feb 1991, In : Molecular and cellular biology. 11, 2, p. 913-919 7 p.

Research output: Contribution to journalArticle

Open Access
81 Scopus citations
1990

Identification of autophosphorylation sites of HER2/neu.

Hazan, R., Margolis, B., Dombalagian, M., Ullrich, A., Zilberstein, A. & Schlessinger, J., Jan 1990, In : Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1, 1, p. 3-7 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: Prognostic significance of erbB-2 protein overexpression in primary breast cancer

Paik, S., Hazan, R., Fisher, E. R., Sass, R. E., Fisher, B., Redmond, C., Schlessinger, J., Lippman, M. E. & King, C. R., 1990, In : Journal of Clinical Oncology. 8, 1, p. 103-112 10 p.

Research output: Contribution to journalArticle

533 Scopus citations
1987

High sensitivity immunolocalization of double and single-stranded DNA by a monoclonal antibody.

Scheer, U., Messner, K., Hazan, R., Raska, I., Hansmann, P., Falk, H., Spiess, E. & Franke, W. W., Jun 1 1987, In : European Journal of Cell Biology. 43, 3, p. 358-371 14 p.

Research output: Contribution to journalArticle

69 Scopus citations

Identification of the bombesin receptor on murine and human cells by cross-linking experiments

Kris, R. M., Hazan, R., Villines, J., Moody, T. W. & Schlessinger, J., Oct 19 1987, In : Journal of Biological Chemistry. 262, 23, p. 11215-11220 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

Di Fiore, P. P., Pierce, J. H., Fleming, T. P., Hazan, R., Ullrich, A., King, C. R., Schlessinger, J. & Aaronson, S. A., Dec 24 1987, In : Cell. 51, 6, p. 1063-1070 8 p.

Research output: Contribution to journalArticle

486 Scopus citations
1986

Change of cytokeratin organization during development of Mallory bodies as revealed by a monoclonal antibody

Hazan, R., Denk, H., Franke, W. F., Lackinger, E. & Schiller, D. L., Oct 1 1986, In : Laboratory Investigation. 54, 5, p. 543-553 11 p.

Research output: Contribution to journalArticle

78 Scopus citations
1985

Localization of ribosomal protein S1 in the granular component of the interphase nucleolus and its distribution during mitosis

Hügle, B., Hazan, R., Scheer, U. & Franke, W. W., Mar 1 1985, In : Journal of Cell Biology. 100, 3, p. 873-886 14 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations
1984
Open Access
79 Scopus citations
1981

Recruitment of effector T lymphocytes by initiator T lymphocytes: application for specific immunosuppression.

Cohen, I. R., Belldegrün, A., Ben-Nun, A. & Hazan, R., Mar 1 1981, In : Transplantation Proceedings. 13, 1 Pt 1, p. 623-625 3 p.

Research output: Contribution to journalArticle

4 Scopus citations