Melissa P. Wasserstein, M.D.

Crandall, J. P., Crandall, J. P., Keller, M. J., Herold, B., Siegal, F., Marom, Z. V. I., Cobin, R., Ginsberg-Fellner, F., Coccaro, E., Caroscio, J., Lipton, J., Warner, R., Ginsberg, H., Bierer, L., Gabrilove, J. L., Paciucci, P., Le, M., Franklin, B., van Woert, M., Conn, M., Miller, M., Schacter, N., Serby, M., Rabin, D., Shiavi, R., Knittle, J., Densnick, R., Dunaif, A., C-Rundles, C., Caccaro, E., Aledort, L., Krakoff, L., Davis, B., Graf, M., Lauer, A., Arthur, K., Yohr, M., Witt, M., Rayfield, E., Miller, C., Davidson, M., Leleiko, N., Cunningham, C., Ginsberg-Fellner, F., Plaitakis, A., Meyers, B., Packer, M., Halpertin, J., Gilbert, H., Roman, S., Cuttner, J., Lawlor, B., Seremetis, S., Schiavi, R., Thys-Jacobs, S., Luckey, M., Larson, S., Grabowski, G., Landrigan, P., Siris, S., Crowell, J., Davies, T., Yahr, M., Cohen, M., Lieberman, K., Krieger, D., Stein, M., Alter, B., Hassett, J., Levine, A., Kupersmith, J., vanwoert, M., Glenn, J., Meier, D., Klotman, M. E., Ambrose, J., Dirocco, A., Min, A., Martignetti, J., Wasserstein, M., Cheung, T., Farren, C., Golier, J., Bovbjerg, D. H., Gelb, B., Morgello, S., Simpson, D., Winston, J., Tuhrim, S., Ferrari, A., Feierman, D., Kaufmann, H., Yehuda, R., Burroughs, M., Christine, E., Vlassara, H., Wong, C., Sampson, H., Rubenstein, A. H., McGovern, M., Wolff, M., Chsebro, J., Brin, M., Grossman, R., Badimon, J. J., Willner, J., Lieberman, F. S., Sung, M., Sutton, M., Vorchheimer, D., Mistry, P., Hall, S., Buchsbaum, M. S., Berkowitz, G. S., Brin, M., New, A., Kase, N., Desnick, R., Wasserstein, M., Cheung, T., Willner, J., Farren, C., Sutton, M., Phillips, R. A., New, A., Schuchman, E., Golier, J., Vorchheimer, D., Bovbjerg, D. H., Gelb, B., Morgello, S., Mistry, P., Lieberman, F. S., Simeon, D., Simpson, D., Winston, J., Tuhrim, S., Chesebro, J., Ferrari, A., Feierman, D., Olanow, C. W., Hall, S., Buchsbaum, M. S., Kaufmann, H., Sacks, H., Yehuda, R., Berkowitz, G. S., Grossman, R., Burroughs, M., Christine, E., Siever, L., Brin, M., Vlassara, H., Wong, C., Sung, M., Sampson, H., Atweh, G., Schneider, A., Dieterich, D. T., Badimon, J. J., Pickering, T., Smith, D., Tuhrim, S., Isola, L., Itzkowitz, S., Baliga, B., Gagner, M., Kaufmann, H., Sierra, M., Busse, P., Prakash-Cheng, A., Bovbjerg, D. H., Ferrari, A., Grossman, H., Erblich, J., Murphy, B. T., Morgenstern, J. O. N., Desnick, R., Ommen, E., Wolberg, J., Gorman, J. M., Golier, J., Banikazemi, M., Bromberg, J., Simpson, D., Yehuda, R., Shneider, B. L., Sacks, H., Hirschowitz, J., Posada, R., Kattan, M., Friedman, J., Fierer, D. S., Rafey, M. A., Johnson-Byrne, J., Clelland, C., Miller, A., Schecter, A., Jang, J., Atweh, G., Schnaider Beeri, M., Goldstein, M., [No Value], M. I., Lipkowitz, M., Schulz, K. P., Herman-Ommen, E., Badimon, J., Greenwald, B., Ambrosone, C. B., Levin, L., Ivanov, I., Silverman, M., Frenette, P., Velinov, M., Sprung, L., Prohovnik, I., Loudon, H., Neade, T., Suchy, F., Borod, J., Reichenberg, A., Olivera, C., Naidich, T., Charney, D. S., New, A., McGovern, M., Morgello, S., Valdimarsdottir, H., Simeon, D., Koenigsberg, H., Buchsbaum, M. S., Siever, L., Sung, M., Sampson, H., Mathew, S., Wolff, M., Lange, D., Nowak-Wegrzyn, A. H., Vlassara, H., Wasserstein, M., Ohnuma, T., Fan, J. I. N., Saland, J., Ryan, E. L., Feder, A., Bartz, J. A., Geer, E. B., Brenner, B., Busse, P., Newcorn, J., Grossman, H., Balwani, M., Erblich, J., Pappagallo, M., Hazlett, E. A., Higgins, S., Goodman, M., Wang, J., Kolevzon, A., Fishbein, D., Wisnivesky, J., Sicherer, S., Anagnostou, A., Ommen, E., Buxbaum, J. D., Ketay, S. B., Kirmse, B. M., Grodberg, D., Ashman, T., Chou, J. C. -., Sacks, H., Murphy, B. T., Shi, P., Diaz, G., Li, X., Aiken, R., Silverman, L., Ozbay, F., Liu, X. U. N., Hollander, E., Hollander, E., Hollander, E., Coller, B., Mohs, R., Lieber, C., Dorfman, D., Miller, C., Gold, G., Kase, N., Borod, J., Pastores, G., Newman, L., Marmur, J., Berkowitz, G., Greenberg, D., Friedman, A., Halperin, J., Arkin, S., Moline, J., Lebwohl, M., Kattan, M., Marin, D., Aisen, P., Trestman, R., Desnick, R., Phillips, R., Schuchman, E., Simeon, D., Chesebro, J., Olanow, C. W., Sacks, H., Siever, L., Atweh, G., Davis, K., Marom, Z. V. I., Gabrilove, J. L., Crowell, J., Klotman, M. E., Bovbjerg, D. H., Rubenstein, A. H., Charney, D. S., Berkowitz, G. S., Phillips, R. A., Bovbjerg, D. H., Olanow, C. W., Berkowitz, G. S., Bovbjerg, D. H., Murphy, B. T., Morgenstern, J. O. N., Gorman, J. M., Shneider, B. L., [No Value], M. I., Schulz, K. P., Fan, J. I. N., Ambrosone, C. B., Hazlett, E. A., Buxbaum, J. D., Ketay, S. B., Chou, J. C. -., Murphy, B. T., Liu, X. U. N., New, A., McGovern, M., Morgello, S., Valdimarsdottir, H., Simeon, D., Koenigsberg, H., Buchsbaum, M. S., Siever, L., Sung, M., Sampson, H., Desnick, R., Wolberg, J., Gorman, J. M., Ommen, E., Golier, J., Banikazemi, M., Bromberg, J., Simpson, D., Yehuda, R., Coller, B., Mohs, R., Lieber, C., Dorfman, D., Miller, C., Gold, G., Kase, N., Borod, J., Pastores, G., Newman, L., Marmur, J., Berkowitz, G., Greenberg, D., Friedman, A., Halperin, J., Arkin, S., Moline, J., Lebwohl, M., Kattan, M., Marin, D., Aisen, P., Trestman, R., Desnick, R., Phillips, R., Schuchman, E., Simeon, D., Chesebro, J., Olanow, C. W., Sacks, H., Siever, L., Atweh, G., Davis, K., Wasserstein, M. P., Wasserstein, M. P. & Wasserstein, M. P.

National Institutes of Health

10/1/75 → 2/28/11

Project: Research project

genetic traits

biomedical research

quality control

genetic techniques and protocols

rodents

Publications 1999 2019

2448 Citations
29 h-Index
56 Article
8 Review article
4 Chapter
2 Comment/debate
1 More
- 1 Letter

Aberrant Function of the C-Terminal Tail of HIST1H1E Accelerates Cellular Senescence and Causes Premature Aging

Flex, E., Martinelli, S., Van Dijck, A., Ciolfi, A., Cecchetti, S., Coluzzi, E., Pannone, L., Andreoli, C., Radio, F. C., Pizzi, S., Carpentieri, G., Bruselles, A., Catanzaro, G., Pedace, L., Miele, E., Carcarino, E., Ge, X., Chijiwa, C., Lewis, M. E. S., Meuwissen, M. & 40 others, Kenis, S., Van der Aa, N., Larson, A., Brown, K., Wasserstein, M. P., Skotko, B. G., Begtrup, A., Person, R., Karayiorgou, M., Roos, J. L., Van Gassen, K. L., Koopmans, M., Bijlsma, E. K., Santen, G. W. E., Barge-Schaapveld, D. Q. C. M., Ruivenkamp, C. A. L., Hoffer, M. J. V., Lalani, S. R., Streff, H., Craigen, W. J., Graham, B. H., van den Elzen, A. P. M., Kamphuis, D. J., Õunap, K., Reinson, K., Pajusalu, S., Wojcik, M. H., Viberti, C., Di Gaetano, C., Bertini, E., Petrucci, S., De Luca, A., Rota, R., Ferretti, E., Matullo, G., Dallapiccola, B., Sgura, A., Walkiewicz, M., Kooy, R. F. & Tartaglia, M., Sep 5 2019, In : American Journal of Human Genetics. 105, 3, p. 493-508 16 p.

Research output: Contribution to journal › Article

Premature Aging

Chromatin Assembly and Disassembly

Cell Aging

Histones

Chromatin

The Genomic Medicine Integrative Research Framework: A Conceptual Framework for Conducting Genomic Medicine Research

Horowitz, C. R., Orlando, L. A., Slavotinek, A. M., Peterson, J., Angelo, F., Biesecker, B., Bonham, V. L., Cameron, L. D., Fullerton, S. M., Gelb, B. D., Goddard, K. A. B., Hailu, B., Hart, R., Hindorff, L. A., Jarvik, G. P., Kaufman, D., Kenny, E. E., Knight, S. J., Koenig, B. A., Korf, B. R. & 7 others, Madden, E., McGuire, A. L., Ou, J., Wasserstein, M. P., Robinson, M., Leventhal, H. & Sanderson, S. C., Jun 6 2019, In : American Journal of Human Genetics. 104, 6, p. 1088-1096 9 p.

Research output: Contribution to journal › Article

Integrative Medicine

Medicine

Research

Translational Medical Research

Program Evaluation

5 Citations (Scopus)

Long-term safety and efficacy of pegvaliase for the treatment of phenylketonuria in adults: Combined phase 2 outcomes through PAL-003 extension study

Longo, N., Zori, R., Wasserstein, M. P., Vockley, J., Burton, B. K., Decker, C., Li, M., Lau, K., Jiang, J., Larimore, K. & Thomas, J. A., Jul 4 2018, In : Orphanet Journal of Rare Diseases. 13, 1, 108.

Research output: Contribution to journal › Article

Phenylketonurias

Phenylalanine

Safety

Phenylalanine Ammonia-Lyase

Social Adjustment

10 Citations (Scopus)

Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months

Wasserstein, M. P., Diaz, G. A., Lachmann, R. H., Jouvin, M. H., Nandy, I., Ji, A. J. & Puga, A. C., Jan 5 2018, (Accepted/In press) In : Journal of Inherited Metabolic Disease. p. 1-10 10 p.

Research output: Contribution to journal › Article

Type A Niemann-Pick Disease

Safety

Acids

Therapeutics

Enzyme Replacement Therapy

2 Citations (Scopus)

Recommendations for clinical monitoring of patients with acid sphingomyelinase deficiency (ASMD)

Wasserstein, M. P., Dionisi-Vici, C., Giugliani, R., Hwu, W. L., Lidove, O., Lukacs, Z., Mengel, E., Mistry, P. K., Schuchman, E. H. & McGovern, M., Jan 1 2018, (Accepted/In press) In : Molecular Genetics and Metabolism.

Research output: Contribution to journal › Article

Type A Niemann-Pick Disease

Sphingomyelin Phosphodiesterase

Physiologic Monitoring

Acids

Monitoring