• 4949 Citations
  • 19 h-Index
20062019

Research output per year

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Publications

  • 4949 Citations
  • 19 h-Index
  • 23 Article
  • 4 Comment/debate
  • 1 Review article
2019

Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts

Bhagat, T. D., Von Ahgrens, D., Dawlaty, M., Zou, Y., Baddour, J., Achreja, A., Zhao, H., Yang, L., Patel, B., Kwak, C., Choudhary, G. S., Gordon-Mitchell, S., Alluri, S., Bhattacharyya, S., Sahu, S., Yu, Y., Bartenstein, M., Giricz, O., Suzuki, M., Sohal, D. & 12 others, Gupta, S., Guerrero, P., Batra, S., Goggins, M., Steidl, U., Greally, J., Agarwal, B., Pradhan, K., Banerjee, D., Nagrath, D., Maitra, A. & Verma, A., Oct 2019, In : eLife. 8, e50663.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis

Ito, K., Lee, J., Chrysanthou, S., Zhao, Y., Josephs, K., Sato, H., Teruya-Feldstein, J., Zheng, D., Dawlaty, M. M. & Ito, K., Sep 3 2019, In : Cell Reports. 28, 10, p. 2480-2490.e4

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells

Ravichandran, M., Lei, R., Tang, Q., Zhao, Y., Lee, J., Ma, L., Chrysanthou, S., Lorton, B. M., Cvekl, A., Shechter, D., Zheng, D. & Dawlaty, M. M., Aug 20 2019, In : Cell Reports. 28, 8, p. 1993-2003.e5

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2017

Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways

Bhattacharyya, S., Pradhan, K., Campbell, N., Mazdo, J., Vasantkumar, A., Maqbool, S., Bhagat, T. D., Gupta, S., Suzuki, M., Yu, Y., Greally, J. M., Steidl, U., Bradner, J., Dawlaty, M., Godley, L., Maitra, A. & Verma, A., Nov 2017, In : Genome research. 27, 11, p. 1830-1842 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

Feng, J., Pena, C. J., Purushothaman, I., Engmann, O., Walker, D., Brown, A. N., Issler, O., Doyle, M., Harrigan, E., Mouzon, E., Vialou, V., Shen, L., Dawlaty, M. M., Jaenisch, R. & Nestler, E. J., Jul 1 2017, In : Neuropsychopharmacology. 42, 8, p. 1657-1669 13 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

Tet1 and Tet2 protect DNA methylation canyons against hypermethylation

Wiehle, L., Raddatz, G., Musch, T., Dawlaty, M. M., Jaenisch, R., Lyko, F. & Breiling, A., 2016, In : Molecular and Cellular Biology. 36, 3, p. 452-461 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs

Yang, J., Guo, R., Wang, H., Ye, X., Zhou, Z., Dan, J., Wang, H., Gong, P., Deng, W., Yin, Y., Mao, S. Q., Wang, L., Ding, J., Li, J., Keefe, D. L., Dawlaty, M. M., Wang, J., Xu, G. L. & Liu, L., May 24 2016, In : Cell Reports. 15, 8, p. 1809-1821 13 p.

Research output: Contribution to journalArticle

31 Scopus citations
2015

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

Zhao, Z., Chen, L., Dawlaty, M. M., Pan, F., Weeks, O., Zhou, Y., Cao, Z., Shi, H., Wang, J., Lin, L., Chen, S., Yuan, W., Qin, Z., Ni, H., Nimer, S. D., Yang, F. C., Jaenisch, R., Jin, P. & Xu, M., Nov 24 2015, In : Cell Reports. 13, 8, p. 1692-1704 13 p.

Research output: Contribution to journalArticle

48 Scopus citations

Erratum: TET1 is a tumor suppressor of hematopoietic malignancy

Cimmino, L., Dawlaty, M. M., Ndiaye-Lobry, D., Yap, Y. S., Bakogianni, S., Yu, Y., Bhattacharyya, S., Shaknovich, R., Geng, H., Lobry, C., Mullenders, J., King, B., Trimarchi, T., Aranda-Orgilles, B., Liu, C., Shen, S., Verma, A. K., Jaenisch, R. & Aifantis, I., Jul 21 2015, In : Nature Immunology. 16, 8, 1 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

TET1 is a tumor suppressor of hematopoietic malignancy

Cimmino, L., Dawlaty, M. M., Ndiaye-Lobry, D., Yap, Y. S., Bakogianni, S., Yu, Y., Bhattacharyya, S., Shaknovich, R., Geng, H., Lobry, C., Mullenders, J., King, B., Trimarchi, T., Aranda-Orgilles, B., Liu, C., Shen, S., Verma, A. K., Jaenisch, R. & Aifantis, I., May 19 2015, In : Nature Immunology. 16, 6, p. 653-662 10 p.

Research output: Contribution to journalArticle

104 Scopus citations
2014

Erratum: Systematic identification of culture conditions for induction and maintenance of naive human pluripotency (Cell Stem Cell (2014) 15 (471-487))

Theunissen, T. W., Powell, B. E., Wang, H., Mitalipova, M., Faddah, D. A., Reddy, J., Fan, Z. P., Maetzel, D., Ganz, K., Shi, L., Lungjangwa, T., Imsoonthornruksa, S., Stelzer, Y., Rangarajan, S., D'Alessio, A., Zhang, J., Gao, Q., Dawlaty, M. M., Young, R. A., Gray, N. S. & 1 others, Jaenisch, R., 2014, In : Cell Stem Cell. 15, 4, p. 524-526 3 p.

Research output: Contribution to journalComment/debate

19 Scopus citations

Erratum: Systematic identification of culture conditions for induction and maintenance of naive human pluripotency (Cell Stem Cell (2014) 15 (471-487))

Theunissen, T. W., Powell, B. E., Wang, H., Mitalipova, M., Faddah, D. A., Reddy, J., Fan, Z. P., Maetzel, D., Ganz, K., Shi, L., Lungjangwa, T., Imsoonthornruksa, S., Stelzer, Y., Rangarajan, S., D'Alessio, A., Zhang, J., Gao, Q., Dawlaty, M. M., Young, R. A., Gray, N. S. & 1 others, Jaenisch, R., 2014, In : Cell Stem Cell. 15, 4, p. 523 1 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Loss of tet enzymes compromises proper differentiation of embryonic stem cells

Dawlaty, M. M., Breiling, A., Le, T., Barrasa, M. I., Raddatz, G., Gao, Q., Powell, B. E., Cheng, A. W., Faull, K. F., Lyko, F. & Jaenisch, R., Apr 14 2014, In : Developmental cell. 29, 1, p. 102-111 10 p.

Research output: Contribution to journalArticle

159 Scopus citations

Systematic identification of culture conditions for induction and maintenance of naive human pluripotency

Theunissen, T. W., Powell, B. E., Wang, H., Mitalipova, M., Faddah, D. A., Reddy, J., Fan, Z. P., Maetzel, D., Ganz, K., Shi, L., Lungjangwa, T., Imsoonthornruksa, S., Stelzer, Y., Rangarajan, S., D'Alessio, A., Zhang, J., Gao, Q., Dawlaty, M. M., Young, R. A., Gray, N. S. & 1 others, Jaenisch, R., 2014, In : Cell Stem Cell. 15, 4, p. 471-487 17 p.

Research output: Contribution to journalArticle

409 Scopus citations
2013

Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

Dawlaty, M. M., Breiling, A., Le, T., Raddatz, G., Barrasa, M. I., Cheng, A. W., Gao, Q., Powell, B. E., Li, Z., Xu, M., Faull, K. F., Lyko, F. & Jaenisch, R., Feb 11 2013, In : Developmental cell. 24, 3, p. 310-323 14 p.

Research output: Contribution to journalArticle

268 Scopus citations

Different Roles for Tet1 and Tet2 Proteins in Reprogramming-Mediated Erasure of Imprints Induced by EGC Fusion

Piccolo, F. M., Bagci, H., Brown, K. E., Landeira, D., Soza-Ried, J., Feytout, A., Mooijman, D., Hajkova, P., Leitch, H. G., Tada, T., Kriaucionis, S., Dawlaty, M. M., Jaenisch, R., Merkenschlager, M. & Fisher, A. G., Mar 28 2013, In : Molecular Cell. 49, 6, p. 1023-1033 11 p.

Research output: Contribution to journalArticle

72 Scopus citations

Errata to Different roles for tet1 and tet2 proteins in reprogramming-mediated erasure of imprints induced by egc fusion [Molecular Cell, 49 (2013) 1023-1033]

Piccolo, F. M., Bagci, H., Brown, K. E., Landeira, D., Soza-Ried, J., Feytout, A., Mooijman, D., Hajkova, P., Leitch, H. G., Tada, T., Kriaucionis, S., Dawlaty, M. M., Jaenisch, R., Merkenschlager, M. & Fisher, A. G., Mar 28 2013, In : Molecular Cell. 49, 6, 1 p.

Research output: Contribution to journalComment/debate

Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan

Baker, D. J., Dawlaty, M. M., Wijshake, T., Jeganathan, K. B., Malureanu, L., Van Ree, J. H., Crespo-Diaz, R., Reyes, S., Seaburg, L., Shapiro, V., Behfar, A., Terzic, A., Van De Sluis, B. & Van Deursen, J. M., Jan 1 2013, In : Nature Cell Biology. 15, 1, p. 96-102 7 p.

Research output: Contribution to journalArticle

155 Scopus citations

One-step generation of mice carrying mutations in multiple genes by CRISPR/cas-mediated genome engineering

Wang, H., Yang, H., Shivalila, C. S., Dawlaty, M. M., Cheng, A. W., Zhang, F. & Jaenisch, R., May 9 2013, In : Cell. 153, 4, p. 910-918 9 p.

Research output: Contribution to journalArticle

2090 Scopus citations

Tet1 is critical for neuronal activity-regulated gene expression and memory extinction

Rudenko, A., Dawlaty, M. M., Seo, J., Cheng, A. W., Meng, J., Le, T., Faull, K. F., Jaenisch, R. & Tsai, L. H., Sep 18 2013, In : Neuron. 79, 6, p. 1109-1122 14 p.

Research output: Contribution to journalArticle

261 Scopus citations

TET1 plays an essential oncogenic role in MLL-rearranged leukemia

Huang, H., Jiang, X., Li, Z., Li, Y., Song, C. X., He, C., Sun, M., Chen, P., Gurbuxani, S., Wang, J., Hong, G. M., Elkahloun, A. G., Arnovitz, S., Wang, J., Szulwach, K., Lin, L., Street, C., Wunderlich, M., Dawlaty, M., Neilly, M. B. & 9 others, Jaenisch, R., Yang, F. C., Mulloy, J. C., Jin, P., Liu, P. P., Rowley, J. D., Xu, M., He, C. & Chen, J., Jul 16 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 29, p. 11994-11999 6 p.

Research output: Contribution to journalArticle

122 Scopus citations
2011

Functional integration of dopaminergic neurons directly converted from mouse fibroblasts

Kim, J., Su, S. C., Wang, H., Cheng, A. W., Cassady, J. P., Lodato, M. A., Lengner, C. J., Chung, C. Y., Dawlaty, M. M., Tsai, L. H. & Jaenisch, R., Nov 4 2011, In : Cell Stem Cell. 9, 5, p. 413-419 7 p.

Research output: Contribution to journalArticle

183 Scopus citations

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

Kim, J., Lengner, C. J., Kirak, O., Hanna, J., Cassady, J. P., Lodato, M. A., Wu, S. U., Faddah, D. A., Steine, E. J., Qing, G. A. O., Fu, D., Dawlaty, M. & Jaenisch, R., Jun 2011, In : STEM CELLS. 29, 6, p. 992-1000 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development

Dawlaty, M. M., Ganz, K., Powell, B. E., Hu, Y. C., Markoulaki, S., Cheng, A. W., Gao, Q., Kim, J., Choi, S. W., Page, D. C. & Jaenisch, R., Aug 5 2011, In : Cell Stem Cell. 9, 2, p. 166-175 10 p.

Research output: Contribution to journalArticle

331 Scopus citations
2010

Reprogramming of human peripheral blood cells to induced pluripotent stem cells

Staerk, J., Dawlaty, M. M., Gao, Q., Maetzel, D., Hanna, J., Sommer, C. A., Mostoslavsky, G. & Jaenisch, R., Jul 2010, In : Cell Stem Cell. 7, 1, p. 20-24 5 p.

Research output: Contribution to journalArticle

267 Scopus citations
2008

Resolution of Sister Centromeres Requires RanBP2-Mediated SUMOylation of Topoisomerase IIα

Dawlaty, M. M., Malureanu, L., Jeganathan, K. B., Kao, E., Sustmann, C., Tahk, S., Shuai, K., Grosschedl, R. & van Deursen, J. M., Apr 4 2008, In : Cell. 133, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

216 Scopus citations
2007

Mitotic regulation of the anaphase-promoting complex

Baker, D. J., Dawlaty, M. M., Galardy, P. & Van Deursen, J. M., Mar 1 2007, In : Cellular and Molecular Life Sciences. 64, 5, p. 589-600 12 p.

Research output: Contribution to journalReview article

67 Scopus citations
2006

Gene targeting methods for studying nuclear transport factors in mice

Dawlaty, M. M. & van Deursen, J. M., Aug 1 2006, In : Methods. 39, 4, p. 370-378 9 p.

Research output: Contribution to journalArticle

12 Scopus citations