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Matthew J. Gamble, Ph.D.

  • 1997 Citations
  • 16 h-Index
19992022
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  • 14 Similar Profiles
Histones Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Histone Code Medicine & Life Sciences
NAD Medicine & Life Sciences
Genes Medicine & Life Sciences
Transcriptional Activation Medicine & Life Sciences
Acetylation Medicine & Life Sciences
Cytoplasmic and Nuclear Receptors Medicine & Life Sciences

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Grants 2008 2022

The role of macroH2A variants in cancer and senescence

Gamble, M. J.

National Institutes of Health

5/4/12 → 3/31/22

Project: Research project

Neoplasms
Histones
Gene Expression
Genome
Poly Adenosine Diphosphate Ribose

Role of MacroH2A in Estrogen-Regulated Gene Expression

Gamble, M. J.

National Institutes of Health

3/5/08 → 3/4/10

Project: Research project

Estrogen Receptors
Estrogens
Chromatin
Gene Expression
NAD

Publications 1999 2019

  • 1997 Citations
  • 16 h-Index
  • 25 Article

MacroH2A1 Regulation of Poly(ADP-Ribose) Synthesis and Stability Prevents Necrosis and Promotes DNA Repair

Ruiz, P. D., Hamilton, G. A., Park, J. W. & Gamble, M. J., Dec 11 2019, In : Molecular and cellular biology. 40, 1

Research output: Contribution to journal › Article

Open Access
Poly Adenosine Diphosphate Ribose
DNA Repair
DNA Damage
Necrosis
NAD
1 Citation (Scopus)

The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening

Kim, J., Sun, C., Tran, A. D., Chin, P. J., Ruiz, P. D., Wang, K., Gibbons, R. J., Gamble, M. J., Liu, Y. & Oberdoerffer, P., Mar 1 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 213-219 7 p.

Research output: Contribution to journal › Article

Telomere Homeostasis
Histones
Telomere
Homologous Recombination
Epigenomics
1 Citation (Scopus)

Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition

Hodge, D. Q., Cui, J., Gamble, M. J. & Guo, W., Dec 1 2018, In : Scientific Reports. 8, 1, 841.

Research output: Contribution to journal › Article

Epithelial-Mesenchymal Transition
Histones
Protein Isoforms
Epigenomics
Stem Cells
1 Citation (Scopus)

MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20

Ruiz, P. D. & Gamble, M. J., Dec 1 2018, In : Nature Communications. 9, 1, 5143.

Research output: Contribution to journal › Article

acetylation
Acetylation
chromatin
lysine
Lysine
2 Citations (Scopus)

S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms

Dulyaninova, N. G., Ruiz, P. D., Gamble, M. J., Backer, J. M. & Bresnicka, A. R., Mar 1 2018, In : Molecular Biology of the Cell. 29, 5, p. 632-642 11 p.

Research output: Contribution to journal › Article

Myosins
Macrophages
Nonmuscle Myosin Type IIA
Chemotaxis
Acetylation