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Kostantin Dobrenis, Ph.D.

  • 2440 Citations
  • 25 h-Index
1987 …2019

Research output per year

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Grants

Zeiss Confocal Microscope with Airyscan for Einstein Neural Cell Engineering and Imaging Core

Dobrenis, K.

NIH Office of the Director

9/2/19 → 8/31/20

Project: Research project

    • Endosomal lysosomal function in neuronal storage disease

    Dobrenis, K. & Walkley, S. U.

    Eunice Kennedy Shriver National Institute of Child Health and Human Development

    7/20/17 → 6/30/18

    Project: Research project

    • Support for the Rose F. Kennedy IDDRC

    Dobrenis, K., Walkley, S. U., Molholm, S., Walkley, S. U., Greally, J. M. & Schwartz, G. J.

    Eunice Kennedy Shriver National Institute of Child Health and Human Development

    9/22/16 → 5/31/17

    Project: Research project

    • Mechanisms of Substrate Reduction Therapy for Niemann-Pick C Disease

    Dobrenis, K. & Walkley, S. U.

    National Institute of Neurological Disorders and Stroke

    2/15/12 → 1/31/13

    Project: Research project

    • GM2 Gangliosidosis Therapy Using Neurotropic Enzyme

    Dobrenis, K.

    National Institute of Neurological Disorders and Stroke

    7/20/09 → 6/30/10

    Project: Research project

    • Publications

    • 2440 Citations
    • 25 h-Index
    • 46 Article
    • 1 Chapter
    • 1 Review article

    Reduced Hippocampal Dendrite Branching, Spine Density and Neurocognitive Function in Premature Rabbits, and Reversal with Estrogen or TrkB Agonist Treatment

    Klebe, D., Tibrewal, M., Sharma, D. R., Vanaparthy, R., Krishna, S., Varghese, M., Cheng, B., Mouton, P. R., Velíšková, J., Dobrenis, K., Hof, P. R. & Ballabh, P., Dec 1 2019, In : Cerebral Cortex. 29, 12, p. 4932-4947 16 p.

    Research output: Contribution to journal › Article

    • Inhibition of Lysosome Membrane Recycling Causes Accumulation of Gangliosides that Contribute to Neurodegeneration

    Boutry, M., Branchu, J., Lustremant, C., Pujol, C., Pernelle, J., Matusiak, R., Seyer, A., Poirel, M., Chu-Van, E., Pierga, A., Dobrenis, K., Puech, J. P., Caillaud, C., Durr, A., Brice, A., Colsch, B., Mochel, F., El Hachimi, K. H., Stevanin, G. & Darios, F., Jun 26 2018, In : Cell Reports. 23, 13, p. 3813-3826 14 p.

    Research output: Contribution to journal › Article

    • 17 Scopus citations

    Pathobiology of Christianson syndrome: Linking disrupted endosomal-lysosomal function with intellectual disability and sensory impairments

    Kerner-Rossi, M., Gulinello, M. E., Walkley, S. U. & Dobrenis, K., Jan 1 2018, (Accepted/In press) In : Neurobiology of Learning and Memory.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice

    Yang, D. S., Stavrides, P., Kumar, A., Jiang, Y., Mohan, P. S., Ohno, M., Dobrenis, K., Davidson, C. D., Saito, M., Pawlik, M., Huo, C., Walkley, S. U. & Nixon, R. A., Mar 1 2017, In : Human molecular genetics. 26, 5, p. 843-859 17 p., ddx001.

    Research output: Contribution to journal › Article

    • 14 Scopus citations

    Diversity of glycosphingolipid GM2 and cholesterol accumulation in NPC1 patient-specific iPSC-derived neurons

    Trilck, M., Peter, F., Zheng, C., Frank, M., Dobrenis, K., Mascher, H., Rolfs, A. & Frech, M. J., Feb 15 2017, In : Brain Research. 1657, p. 52-61 10 p.

    Research output: Contribution to journal › Article

    • 6 Scopus citations