• 1615 Citations
  • 12 h-Index
1994 …2021
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  • 9 Similar Profiles
Acute Myeloid Leukemia Medicine & Life Sciences
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Leukemia Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Zebrafish Medicine & Life Sciences
Hematopoiesis Medicine & Life Sciences

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Grants 2010 2021

Myeloid Leukemia
Hematopoiesis
Phosphatidylinositol 3-Kinases
Protein Isoforms
Acute Myeloid Leukemia

The p110 alpha and delta isoforms of PI3 kinase in hematopoiesis and leukemia

Gritsman, K.

National Institutes of Health

9/15/108/31/15

Project: Research projectClinical Investigator Award (CIA)

Hematopoiesis
Phosphatidylinositol 3-Kinases
Protein Isoforms
Leukemia
Hematopoietic Stem Cells

Publications 1994 2018

  • 1615 Citations
  • 12 h-Index
  • 20 Article
  • 1 Review article
2 Citations

IL1RAP potentiates multiple oncogenic signaling pathways in AML

Mitchell, K., Barreyro, L., Todorova, T. I., Taylor, S. J., Antony-Debré, I., Narayanagari, S-R., Carvajal, L. A., Leite, J., Piperdi, Z., Pendurti, G., Mantzaris, I., Paietta, E. M., Verma, A. K., Gritsman, K. & Steidl, U. G., Jun 1 2018, In : Journal of Experimental Medicine. 215, 6, p. 1709-1727 19 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptor Accessory Protein
Acute Myeloid Leukemia
Interleukin-1 Receptors
Receptor Protein-Tyrosine Kinases
Protein Transport
1 Citations

North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies

Shah, U. A., Chung, E. Y. L., Giricz, O., Pradhan, K., Kataoka, K., Gordon-Mitchel, S., Bhagat, T. D., Mai, Y., Wei, Y., Ishida, E., Choudhary, G. S., Joseph, A., Rice, R., Gitego, N., Parrish, C., Bartenstein, M., Goel, S., Mantzaris, I., Shastri, A., Derman, O. & 13 othersBinder, A., Gritsman, K., Kornblum, N., Braunschweig, I., Bhagat, C., Hall, J., Graber, A., Ratner, L., Wang, Y., Ogawa, S., Verma, A. K., Ye, B. H. & Janakiram, M., Oct 4 2018, In : Blood. 132, 14, p. 1507-1518 12 p.

Research output: Contribution to journalArticle

Adult T Cell Leukemia Lymphoma
T-cells
Epigenomics
decitabine
Mutation Rate

A myeloid tumor suppressor role for NOL3

Stanley, R. F., Piszczatowski, R. T., Bartholdy, B. A., Mitchell, K., McKimpson, W. M., Narayanagari, S-R., Walter, D., Todorova, T. I., Hirsch, C., Makishima, H., Will, B., McMahon, C., Gritsman, K., Maciejewski, J. P., Kitsis, R. N. & Steidl, U. G., Mar 6 2017, In : The Journal of experimental medicine. 214, 3, p. 753-771 19 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Neoplasms
Nuclear Proteins
Cyclin-Dependent Kinase 6
Cell Biology
10 Citations

Epigenetically aberrant stroma in MDS propagates disease via Wnt/β-catenin activation

Bhagat, T. D., Chen, S., Bartenstein, M., Barlowe, A. T., Von Ahrens, D., Choudhary, G. S., Tivnan, P., Amin, E., Marcondes, A. M., Sanders, M. A., Hoogenboezem, R. M., Kambhampati, S., Ramachandra, N., Mantzaris, I., Sukrithan, V., Laurence, R., Lopez, R., Bhagat, P., Giricz, O., Sohal, D. & 18 othersWickrema, A., Yeung, C., Gritsman, K., Aplan, P., Hochedlinger, K., Yu, Y., Pradhan, K., Zhang, J., Greally, J. M., Mukherjee, S., Pellagatti, A., Boultwood, J., Will, B., Steidl, U. G., Raaijmakers, M. H. G. P., Deeg, H. J., Kharas, M. G. & Verma, A. K., Sep 15 2017, In : Cancer Research. 77, 18, p. 4846-4857 12 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
beta Catenin
Catenins
Bone Marrow
Methyltransferases

Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia

Darbinyan, K., Shastri, A., Budhathoki, A., Helbig, D., Snyder, R., Pradhan, K., Saleh-Esa, J., Kornblum, N., Binder, A. F., Goel, S., Janakiram, M., Derman, O., Gritsman, K., Steidl, U. G., Braunschweig, I., Verma, A. & Mantzaris, I., Nov 14 2017, In : Blood advances. 1, 24, p. 2120-2123 4 p.

Research output: Contribution to journalArticle

Hispanic Americans
Acute Myeloid Leukemia
Mutation