• 1556 Citations
  • 12 h-Index
1994 …2021
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  • 11 Similar Profiles
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Leukemia Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Zebrafish Medicine & Life Sciences
Hematopoiesis Medicine & Life Sciences

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Grants 2010 2021

Myeloid Leukemia
Hematopoiesis
Phosphatidylinositol 3-Kinases
Protein Isoforms
Acute Myeloid Leukemia

The p110 alpha and delta isoforms of PI3 kinase in hematopoiesis and leukemia

Gritsman, K.

National Institutes of Health

9/15/108/31/15

Project: Research projectClinical Investigator Award (CIA)

Hematopoiesis
Phosphatidylinositol 3-Kinases
Protein Isoforms
Leukemia
Hematopoietic Stem Cells

Publications 1994 2018

  • 1556 Citations
  • 12 h-Index
  • 18 Article
  • 1 Review article

IL1RAP potentiates multiple oncogenic signaling pathways in AML

Mitchell, K., Barreyro, L., Todorova, T. I., Taylor, S. J., Antony-Debré, I., Narayanagari, S. R., Carvajal, L. A., Leite, J., Piperdi, Z., Pendurti, G., Mantzaris, I., Paietta, E., Verma, A., Gritsman, K. & Steidl, U., Jun 1 2018, In : Journal of Experimental Medicine. 215, 6, p. 1709-1727 19 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptor Accessory Protein
Acute Myeloid Leukemia
Interleukin-1 Receptors
Receptor Protein-Tyrosine Kinases
Protein Transport

A myeloid tumor suppressor role for NOL3

Stanley, R. F., Piszczatowski, R. T., Bartholdy, B., Mitchell, K., McKimpson, W. M., Narayanagari, S., Walter, D., Todorova, T. I., Hirsch, C., Makishima, H., Will, B., McMahon, C., Gritsman, K., Maciejewski, J. P., Kitsis, R. N. & Steidl, U., Mar 6 2017, In : The Journal of experimental medicine. 214, 3, p. 753-771 19 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Neoplasms
Nuclear Proteins
Cyclin-Dependent Kinase 6
Cell Biology
3 Citations

Epigenetically aberrant stroma in MDS propagates disease via Wnt/β-catenin activation

Bhagat, T. D. , Chen, S. , Bartenstein, M. , Barlowe, A. T. , Von Ahrens, D. , Choudhary, G. S. , Tivnan, P. , Amin, E. , Marcondes, A. M. , Sanders, M. A. , Hoogenboezem, R. M. , Kambhampati, S. , Ramachandra, N. , Mantzaris, I. , Sukrithan, V. , Laurence, R. , Lopez, R. , Bhagat, P. , Giricz, O. , Sohal, D. & 18 others Wickrema, A., Yeung, C., Gritsman, K., Aplan, P., Hochedlinger, K., Yu, Y., Pradhan, K., Zhang, J., Greally, J. M., Mukherjee, S., Pellagatti, A., Boultwood, J., Will, B., Steidl, U., Raaijmakers, M. H. G. P., Deeg, H. J., Kharas, M. G. & Verma, A., Sep 15 2017, In : Cancer Research. 77, 18, p. 4846-4857 12 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
beta Catenin
Catenins
Bone Marrow
Methyltransferases
3 Citations

Inflammatory signaling pathways in preleukemic and leukemic stem cells

Hemmati, S., Haque, T. & Gritsman, K., Nov 13 2017, In : Frontiers in Oncology. 7, NOV, 265

Research output: Contribution to journalReview article

Hematopoietic Stem Cells
Stem Cells
Acute Myeloid Leukemia
Bone Marrow
Myelopoiesis
42 Citations

Control of the innate immune response by the mevalonate pathway

Akula, M. K. , Shi, M. , Jiang, Z. , Foster, C. E. , Miao, D. , Li, A. S. , Zhang, X. , Gavin, R. M. , Forde, S. D. , Germain, G. , Carpenter, S. , Rosadini, C. V. , Gritsman, K. , Chae, J. J. , Hampton, R. , Silverman, N. , Gravallese, E. M. , Kagan, J. C. , Fitzgerald, K. A. , Kastner, D. L. & 3 others Golenbock, D. T., Bergo, M. O. & Wang, D., Jun 6 2016, (Accepted/In press) In : Nature Immunology.

Research output: Contribution to journalArticle

Protein Prenylation
Inflammasomes
Mevalonic Acid
Phosphatidylinositol 3-Kinases
Innate Immunity