• 2482 Citations
  • 15 h-Index
19942013
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Fingerprint Dive into the research topics where Ken Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Transgenic Mice Medicine & Life Sciences
myc Genes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Yeasts Medicine & Life Sciences
Human immunodeficiency virus 1 Agriculture & Biology
Tumor Suppressor Genes Medicine & Life Sciences
Sin3 Histone Deacetylase and Corepressor Complex Medicine & Life Sciences
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Medicine & Life Sciences

Publications 1994 2013

  • 2482 Citations
  • 15 h-Index
  • 16 Article
21 Citations (Scopus)

Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A New Model for Investigating HIV-1 Transmission and Treatment Efficacy

Seay, K., Qi, X., Zheng, J. H., Zhang, C., Chen, K., Dutta, M., Deneroff, K., Ochsenbauer, C., Kappes, J. C., Littman, D. R. & Goldstein, H., May 15 2013, In : PLoS One. 8, 5, e63537.

Research output: Contribution to journalArticle

Cyclin T
cyclins
Human immunodeficiency virus 1
Luciferases
Transgenic Mice
58 Citations (Scopus)

Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody

Joseph, A., Zheng, J. H., Chen, K., Dutta, M., Chen, C., Stiegler, G., Kunert, R., Follenzi, A. & Goldstein, H., Jul 2010, In : Journal of Virology. 84, 13, p. 6645-6653 9 p.

Research output: Contribution to journalArticle

HIV Antibodies
gene therapy
HIV infections
Hematopoietic Stem Cells
Neutralizing Antibodies
68 Citations (Scopus)

Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity

Joseph, A., Jian, H. Z., Follenzi, A., DiLorenzo, T. P., Sango, K., Hyman, J., Chen, K., Piechocka-Trocha, A., Brander, C., Hooijberg, E., Vignali, D. A., Walker, B. D. & Goldstein, H., Mar 2008, In : Journal of Virology. 82, 6, p. 3078-3089 12 p.

Research output: Contribution to journalArticle

T-Cell Receptor Genes
cytotoxic T-lymphocytes
Cytotoxic T-Lymphocytes
Human immunodeficiency virus 1
HIV-1
21 Citations (Scopus)

Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice

Huang, S., Liang, J., Zheng, M., Li, X., Wang, M., Wang, P., Vanegas, D., Wu, D., Chakraborty, B., Hays, A. P., Chen, K., Chen, S. G., Booth, S., Cohen, M., Gambetti, P. & Kong, Q., Apr 17 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 16, p. 6800-6805 6 p.

Research output: Contribution to journalArticle

Muscular Diseases
Transgenic Mice
Muscles
Doxycycline
Prion Proteins
57 Citations (Scopus)

Conditional deletion of the colony stimulating factor-1 receptor (c-fms proto-oncogene) in mice

Li, J., Chen, K., Zhu, L. & Pollard, J. W., Jul 2006, In : Genesis. 44, 7, p. 328-335 8 p.

Research output: Contribution to journalArticle

fms Genes
Colony-Stimulating Factor Receptors
Macrophage Colony-Stimulating Factor
Alleles
Phenotype