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Ebolavirus Medicine & Life Sciences
Glycoproteins Medicine & Life Sciences
Peptides Medicine & Life Sciences
Antibodies Medicine & Life Sciences
Viruses Chemical Compounds
Marburgvirus Medicine & Life Sciences
Bispecific Antibodies Medicine & Life Sciences
Virus Internalization Medicine & Life Sciences

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Grants 2010 2021

Ebolavirus
Monoclonal Antibodies
Antibodies
Marburgvirus
Viruses

Engineered Dengue EDIIIs as Broad Immunogens

Lai, J. R.

National Institutes of Health

1/1/1712/31/18

Project: Research projectExploratory/Developmental Grants

Dengue
Subunit Vaccines
Glycoproteins
Infection
Flavivirus

Consortium for Immunotherapeutics Against Viral Hemorrhagic Fevers

Lai, J. R. & Chandran, K.

National Institutes of Health

3/15/142/28/19

Project: Research projectResearch Program--Cooperative Agreements

Ebolavirus
Virology
Marburgvirus
Monoclonal Antibodies
Antibodies

Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease

Lai, J. R.

National Institutes of Health

7/5/166/30/17

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase I

Ebola Hemorrhagic Fever
Bispecific Antibodies
Epitopes
Ebolavirus
Antibodies

Methods to Identify High-Affinity Antibodies that Target Tumor-Associated Glycans

Lai, J. R.

National Institutes of Health

7/1/116/30/14

Project: Research projectExploratory/Developmental Grants

Neoplasm Antibodies
Antibody Affinity
Polysaccharides
Antibodies
Neoplasms

Publications 2001 2018

  • 1250 Citations
  • 21 h-Index
  • 50 Article
  • 1 Review article

Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins

Nyakatura, E. K., Zak, S. E., Wec, A. Z., Hofmann, D., Shulenin, S., Bakken, R. R., Javad Aman, M., Chandran, K., Dye, J. M. & Lai, J. R. Jan 1 2018 In : Journal of Biological Chemistry. 293, 16, p. 6201-6211 11 p.

Research output: Contribution to journalArticle

Delta wing aircraft
Hangars
Ebolavirus
Bispecific Antibodies
Glycoproteins
9 Citations

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses

Wec, A. Z. , Herbert, A. S. , Murin, C. D. , Nyakatura, E. K. , Abelson, D. M. , Fels, J. M. , He, S. , James, R. M. , de La Vega, M. A. , Zhu, W. , Bakken, R. R. , Goodwin, E. , Turner, H. L. , Jangra, R. K. , Zeitlin, L. , Qiu, X. , Lai, J. R. , Walker, L. M. , Ward, A. B. , Dye, J. M. & 2 others Chandran, K. & Bornholdt, Z. A. May 18 2017 In : Cell. 169, 5, p. 878-890.e15

Research output: Contribution to journalArticle

Ebolavirus
Glycoproteins
Antibodies
Ebola Hemorrhagic Fever
Fusion reactions
1 Citations

Bispecific antibodies for viral immunotherapy

Nyakatura, E. K., Soare, A. Y. & Lai, J. R. Apr 3 2017 In : Human vaccines & immunotherapeutics. 13, 4, p. 836-842 7 p.

Research output: Contribution to journalReview article

Bispecific Antibodies
Immunotherapy
Epitopes
Monoclonal Antibodies
Inflammation
1 Citations

Exploring human antimicrobial antibody responses on a single B cell level

Hofmann, D. & Lai, J. R. May 1 2017 In : Clinical and Vaccine Immunology. 24, 5, e00544

Research output: Contribution to journalArticle

Antibody Formation
B-Lymphocytes
Cloning
Cells
Pathogens
Bacteriophages
Libraries
Polysaccharides
Display devices
Antibodies