Jonathan R. Lai, Ph.D.

Wec, A. Z. , Herbert, A. S. , Murin, C. D. , Nyakatura, E. K. , Abelson, D. M. , Fels, J. M. , He, S. , James, R. M. , de La Vega, M. A. , Zhu, W. , Bakken, R. R. , Goodwin, E. , Turner, H. L. , Jangra, R. K. , Zeitlin, L. , Qiu, X. , Lai, J. R. , Walker, L. M. , Ward, A. B. , Dye, J. M. & 2 others Chandran, K. & Bornholdt, Z. A. May 18 2017 In : Cell. 169, 5, p. 878-890.e15

Research output: Contribution to journal › Article

Ebolavirus

Glycoproteins

Antibodies

Fusion reactions

Infection

Bispecific antibodies for viral immunotherapy

Nyakatura, E. K., Soare, A. Y. & Lai, J. R. Apr 3 2017 In : Human vaccines & immunotherapeutics. 13, 4, p. 836-842 7 p.

Research output: Contribution to journal › Review article

Bispecific Antibodies

Immunotherapy

Epitopes

Monoclonal Antibodies

Inflammation

Exploring human antimicrobial antibody responses on a single B cell level

Hofmann, D. & Lai, J. R. May 1 2017 In : Clinical and Vaccine Immunology. 24, 5, e00544

Research output: Contribution to journal › Article

Antibody Formation

B-Lymphocytes

Castration

Immunotherapy

Organism Cloning

15 Citations

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

Howell, K. A. , Qiu, X. , Brannan, J. M. , Bryan, C. , Davidson, E. , Holtsberg, F. W. , Wec, A. Z. , Shulenin, S. , Biggins, J. E. , Douglas, R. , Enterlein, S. G. , Turner, H. L. , Pallesen, J. , Murin, C. D. , He, S. , Kroeker, A. , Vu, H. , Herbert, A. S. , Fusco, M. L. , Nyakatura, E. K. & 11 others Lai, J. R., Keck, Z. Y., Foung, S. K. H., Saphire, E. O., Zeitlin, L., Ward, A. B., Chandran, K., Doranz, B. J., Kobinger, G. P., Dye, J. M. & Aman, M. J. May 17 2016 In : Cell Reports. 15, 7, p. 1514-1526 13 p.

Research output: Contribution to journal › Article

Ebolavirus

Epitopes

Glycoproteins

Binding Sites

Antibodies

10 Citations

A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses

Wec, A. Z., Nyakatura, E. K., Herbert, A. S., Howell, K. A., Holtsberg, F. W., Bakken, R. R., Mittler, E., Christin, J. R., Shulenin, S., Jangra, R. K., Bharrhan, S., Kuehne, A. I., Bornholdt, Z. A., Flyak, A. I., Saphire, E. O., Crowe, J. E., Aman, M. J., Dye, J. M., Lai, J. R. & Chandran, K. Oct 21 2016 In : Science. 354, 6310, p. 350-354 5 p.

Research output: Contribution to journal › Article

Ebolavirus

Bispecific Antibodies

Monoclonal Antibodies

Endosomes

Virion