Projects per year
Fingerprint Dive into the research topics where Jonathan R. Lai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Ebolavirus
Medicine & Life Sciences
Glycoproteins
Medicine & Life Sciences
Antibodies
Medicine & Life Sciences
Viruses
Chemical Compounds
Peptides
Medicine & Life Sciences
Monoclonal Antibodies
Medicine & Life Sciences
Marburgvirus
Medicine & Life Sciences
Epitopes
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2010 2022
A Trojan Horse bispecific antibody strategy for broad filovirus therapeutics
7/14/17 → 6/30/22
Project: Research project
Bispecific Antibodies
Monoclonal Antibodies
Ebolavirus
Epitopes
Sudan
Engineered, multispecific antibodies as broad anti-filovirus therapeutics
6/1/17 → 5/31/21
Project: Research project
Ebolavirus
Monoclonal Antibodies
Antibodies
Marburgvirus
Viruses
Consortium for Immunotherapeutics Against Viral Hemorrhagic Fevers
3/15/14 → 2/29/20
Project: Research project
Ebolavirus
Virology
Marburgvirus
Monoclonal Antibodies
Antibodies
Dengue
Subunit Vaccines
Glycoproteins
Infection
Flavivirus
Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease
7/5/16 → 6/30/19
Project: Research project
Ebola Hemorrhagic Fever
Bispecific Antibodies
Ebolavirus
Viruses
Antibodies
Publications 2001 2019
Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins
Quiroz, J. A., Malonis, R. J., Thackray, L. B., Cohen, C. A., Pallesen, J., Jangra, R. K., Brown, R. S., Hofmann, D., Holtsberg, F. W., Shulenin, S., Nyakatura, E. K., Durnell, L. A., Rayannavar, V., Daily, J. P., Ward, A. B., Aman, M. J., Dye, J. M., Chandran, K., Diamond, M. S., Kielian, M. & 1 others, , Nov 1 2019, In : PLoS pathogens. 15, 11, p. e1008061Research output: Contribution to journal › Article
Open Access
Chikungunya virus
Epitopes
Glycoproteins
Monoclonal Antibodies
Dominican Republic
Isolation of Synthetic Antibodies Against BCL-2-Associated X Protein (BAX)
Dai, Z. & Lai, J. R., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 351-357 7 p. (Methods in Molecular Biology; vol. 1877).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Antibodies
Proteins
Immunoglobulin Fragments
Mitochondrial Membranes
Bacteriophages
22
Citations
(Scopus)
A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus
Gunn, B. M., Yu, W. H., Karim, M. M., Brannan, J. M., Herbert, A. S., Wec, A. Z., Halfmann, P. J., Fusco, M. L., Schendel, S. L., Gangavarapu, K., Krause, T., Qiu, X., He, S., Das, J., Suscovich, T. J., Lai, J. R., Chandran, K., Zeitlin, L., Crowe, J. E., Lauffenburger, D. & 6 others, , Aug 8 2018, In : Cell Host and Microbe. 24, 2, p. 221-233.e5Research output: Contribution to journal › Article
Ebolavirus
Monoclonal Antibodies
Antibodies
Therapeutics
Neutralizing Antibodies
4
Citations
(Scopus)
Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins
Nyakatura, E. K., Zak, S. E., Wec, A. Z., Hofmann, D., Shulenin, S., Bakken, R. R., Javad Aman, M., Chandran, K., Dye, J. M. & Lai, J. R., Jan 1 2018, In : Journal of Biological Chemistry. 293, 16, p. 6201-6211 11 p.Research output: Contribution to journal › Article
Ebolavirus
Bispecific Antibodies
Viruses
Glycoproteins
Marburgvirus
5
Citations
(Scopus)
Engineered dengue virus domain III proteins elicit cross-neutralizing antibody responses in mice
Frei, J. C., Wirchnianski, A. S., Govero, J., Vergnolle, O. M., Dowd, K. A., Pierson, T. C., Kielian, M., Girvin, M. E., Diamond, M. S. & Lai, J. R., Sep 1 2018, In : Journal of Virology. 92, 18, e01023.Research output: Contribution to journal › Article
Dengue virus
Dengue Virus
Neutralizing Antibodies
neutralizing antibodies
Antibody Formation