Projects per year
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Dive into the research topics where James C.M. Brust is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Mentoring of multidisciplinary global health research in tuberculosis and HIV
National Institute of Allergy and Infectious Diseases
7/1/21 → 6/30/22
Project: Research project
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Emergence of bedaquiline and clofazimine resistance after interruption of drug-resistant TB therapy in a high HIV prevalence setting
12/26/19 → 11/30/24
Project: Research project
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Safety, pharmacokinetics, and resistance to bedaquiline in XDR TB and HIV
2/5/15 → 1/31/21
Project: Research project
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Safety, pharmacokinetics, and resistance to bedaquiline in XDR TB and HIV
National Institute of Allergy and Infectious Diseases
2/5/15 → 1/31/21
Project: Research project
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Evidence-based definition for extensively drug-resistant tuberculosis
Roelens, M., Migliori, G. B., Rozanova, L., Estill, J., Campbell, J. R., Cegielski, J. P., Tiberi, S., Palmero, D., Fox, G. J., Guglielmetti, L., Sotgiu, G., Brust, J. C. M., Bang, D., Lienhardt, C., Lange, C., Menzies, D., Keiser, O. & Raviglione, M., Sep 15 2021, In: American journal of respiratory and critical care medicine. 204, 6, p. 713-722 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Relationship between plasma and intracellular concentrations of bedaquiline and its m2 metabolite in South African patients with rifampin-resistant tuberculosis
Ngwalero, P., Brust, J. C. M., van Beek, S. W., Wasserman, S., Maartens, G., Meintjes, G., Joubert, A., Norman, J., Castel, S., Gandhi, N. R., Denti, P., McIlleron, H., Svensson, E. M. & Wiesner, L., Nov 2021, In: Antimicrobial agents and chemotherapy. 65, 11, e02399-20.Research output: Contribution to journal › Article › peer-review
Open Access -
TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis
Collins, J. M., Jones, D. P., Sharma, A., Khadka, M., Liu, K. H., Kempker, R. R., Prideaux, B., Maner-Smith, K., Tukvadze, N., Shah, N. S., Brust, J. C. M., Sekaly, R. P., Gandhi, N. R., Blumberg, H. M., Ortlund, E. A. & Ziegler, T. R., Sep 2021, In: PLoS pathogens. 17, 9, e1009941.Research output: Contribution to journal › Article › peer-review
Open Access -
Clofazimine pharmacokinetics in patients with TB: Dosing implications
Abdelwahab, M. T., Wasserman, S., Brust, J. C. M., Gandhi, N. R., Meintjes, G., Everitt, D., Diacon, A., Dawson, R., Wiesner, L., Svensson, E. M., Maartens, G. & Denti, P., Nov 1 2020, In: Journal of Antimicrobial Chemotherapy. 75, 11, p. 3269-3277 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis
Lan, Z., Ahmad, N., Baghaei, P., Barkane, L., Benedetti, A., Brode, S. K., Brust, J. C. M., Campbell, J. R., Chang, V. W. L., Falzon, D., Guglielmetti, L., Isaakidis, P., Kempker, R. R., Kipiani, M., Kuksa, L., Lange, C., Laniado-Laborín, R., Nahid, P., Rodrigues, D., Singla, R. & 21 others, , Apr 2020, In: The Lancet Respiratory Medicine. 8, 4, p. 383-394 12 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations