• 1257 Citations
  • 19 h-Index
1975 …2024

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Article
2020

Capsular glycan recognition provides antibody-mediated immunity against tuberculosis

Chen, T., Blanc, C., Liu, Y., Ishida, E., Singer, S., Xu, J., Joe, M., Jenny-Avital, E. R., Chan, J., Lowary, T. L. & Achkar, J. M., Apr 1 2020, In : Journal of Clinical Investigation. 130, 4, p. 1808-1822 15 p.

Research output: Contribution to journalArticle

Open Access

Effects of anticoagulants and Ficoll on human serum antibody reactivities and functions against Mycobacterium tuberculosis

Gadsden, N. J., Liu, Y., Gati, S., Chen, T., Jenny-Avital, E. R. & Achkar, J. M., Jan 2020, In : Tuberculosis. 120, 101901.

Research output: Contribution to journalArticle

Open Access
2019

Combining urine lipoarabinomannan with antibody detection as a simple non-sputum-based screening method for HIV-associated tuberculosis

Younis, H., Kerschbaumer, I., Moon, J. Y., Kim, R. S., Blanc, C. J., Chen, T., Wood, R., Lawn, S. & Achkar, J. M., Jan 1 2019, In : PloS one. 14, 6, p. e0218606

Research output: Contribution to journalArticle

Open Access

Factors Associated With Sputum Culture-Negative vs Culture-Positive Diagnosis of Pulmonary Tuberculosis

Nguyen, M. V. H., Levy, N. S., Ahuja, S. D., Trieu, L., Proops, D. C. & Achkar, J. M., Feb 1 2019, In : JAMA Network Open. 2, 2, p. e187617

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Serum-Mediated Cleavage of Bacillus anthracis Protective Antigen Is a Two-Step Process That Involves a Serum Carboxypeptidase

Goldman, D. L., Nieves, E., Nakouzi, A., Rivera, J., Phyu, E. E., Win, T. H., Achkar, J. M. & Casadevall, A., Jun 27 2018, In : mSphere. 3, 3

Research output: Contribution to journalArticle

1 Scopus citations

Soluble CD14 as a diagnostic biomarker for smear-negative HIV-associated tuberculosis

Liu, Y., Ndumnego, O. C., Chen, T., Kim, R. S., Jenny-Avital, E. R., Ndung’u, T., Wilson, D. & Achkar, J. M., Mar 2018, In : Pathogens. 7, 1, 26.

Research output: Contribution to journalArticle

2 Scopus citations

Utilization and clinical value of diagnostic modalities for tuberculosis in a high HIV prevalence setting

Gati, S., Chetty, R., Wilson, D. & Achkar, J. M., Jan 1 2018, In : American Journal of Tropical Medicine and Hygiene. 99, 2, p. 317-322 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine

Prados-Rosales, R., Carreño, L., Cheng, T., Blanc, C., Weinrick, B., Malek, A., Lowary, T. L., Baena, A., Joe, M., Bai, Y., Kalscheuer, R., Batista-Gonzalez, A., Saavedra, N. A., Sampedro, L., Tomás, J., Anguita, J., Hung, S. C., Tripathi, A., Xu, J., Glatman-Freedman, A. & 5 others, Jacobs, W. R., Chan, J., Porcelli, S. A., Achkar, J. M. & Casadevall, A., Mar 2017, In : PLoS pathogens. 13, 3, e1006250.

Research output: Contribution to journalArticle

41 Scopus citations

Identification of antibody targets for tuberculosis serology using High-Density Nucleic Acid Programmable Protein Arrays

Song, L., Wallstrom, G., Yu, X., Hopper, M., Van Duine, J., Steel, J., Park, J., Wiktor, P., Kahn, P., Brunner, A., Wilson, D., Jenny-Avital, E. R., Qiu, J., Labaer, J., Magee, D. M. & Achkar, J. M., Apr 1 2017, In : Molecular and Cellular Proteomics. 16, 4, p. S277-S289

Research output: Contribution to journalArticle

19 Scopus citations

Multiplexed Nucleic Acid programmable protein arrays

Yu, X., Song, L., Petritis, B., Bian, X., Wang, H., Viloria, J., Park, J., Bui, H., Li, H., Wang, J., Liu, L., Yang, L., Duan, H., McMurray, D. N., Achkar, J. M., Magee, M., Qiu, J. & LaBaer, J., 2017, In : Theranostics. 7, 16, 20151.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Association of Human Antibodies to Arabinomannan with Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction

Chen, T., Blanc, C., Eder, A. Z., Prados-Rosales, R., Souza, A. C. O., Kim, R. S., Glatman-Freedman, A., Joe, M., Bai, Y., Lowary, T. L., Tanner, R., Brennan, M. J., Fletcher, H. A., McShane, H., Casadevall, A. & Achkar, J. M., Jul 15 2016, In : Journal of Infectious Diseases. 214, 2, p. 300-310 11 p.

Research output: Contribution to journalArticle

48 Scopus citations
2015

B cells and antibodies in the defense against Mycobacterium tuberculosis infection

Achkar, J. M., Chan, J. & Casadevall, A., Mar 1 2015, In : Immunological Reviews. 264, 1, p. 167-181 15 p.

Research output: Contribution to journalArticle

90 Scopus citations

Clinical and radiographic manifestations of sputum culture-negative pulmonary tuberculosis

Nguyen, M. V. H., Jenny-Avital, E. R., Burger, S., Leibert, E. M. & Achkar, J. M., Oct 8 2015, In : PloS one. 10, 10, e0140003.

Research output: Contribution to journalArticle

9 Scopus citations

Developing aerosol vaccines for Mycobacterium tuberculosis: Workshop proceedings. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA, April 9, 2014.

Aerosol Vaccines for Tuberculosis Workshop Summary Group, Jun 12 2015, In : Vaccine. 33, 26, p. 3038-3046 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Host Protein Biomarkers Identify Active Tuberculosis in HIV Uninfected and Co-infected Individuals

Achkar, J. M., Cortes, L., Croteau, P., Yanofsky, C., Mentinova, M., Rajotte, I., Schirm, M., Zhou, Y., Junqueira-Kipnis, A. P., Kasprowicz, V. O., Larsen, M., Allard, R., Hunter, J. & Paramithiotis, E., Sep 1 2015, In : EBioMedicine. 2, 9, p. 1160-1168 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

National trends in benign pulmonary resections: Association with CT and PET imaging

Hsu, L., Achkar, J. M., Keller, S. M., Bailey, J. J., Cohen, H. W. & Haramati, L. B., Feb 1 2015, In : Chest. 147, 2, p. e61-e62

Research output: Contribution to journalArticle

Role of B cells and antibodies in acquired immunity against Mycobacterium tuberculosis

Achkar, J. M., Chan, J. & Casadevall, A., Jan 1 2015, In : Cold Spring Harbor Perspectives in Medicine. 5, 3, a018432.

Research output: Contribution to journalArticle

15 Scopus citations
2014

Antibodies against mycobacterial proteins as biomarkers for HIV-associated smear-negative tuberculosis

Siev, M., Wilson, D., Kainth, S., Kasprowicz, V. O., Feintuch, C. M., Jenny-Avital, E. R. & Achkar, J. M., Jun 2014, In : Clinical and Vaccine Immunology. 21, 6, p. 791-798 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mycobacterial membrane vesicles administered systemically in mice induce a protective immune response to surface compartments of mycobacterium tuberculosis

Prados-Rosales, R., Carreño, L. J., Batista-Gonzalez, A., Baena, A., Venkataswamy, M. M., Xu, J., Yu, X., Wallstrom, G., Mitchell Magee, D., LaBaer, J., Achkar, J. M., Jacobs, W. R., Chan, J., Porcelli, S. A. & Casadevall, A., Sep 30 2014, In : mBio. 5, 5, e01921-14.

Research output: Contribution to journalArticle

44 Scopus citations
2013

Diagnosis and inflammatory response of patients with candiduria

Helbig, S., Achkar, J. M., Jain, N., Wang, X., Gialanella, P., Levi, M. & Fries, B. C., Jan 1 2013, In : Mycoses. 56, 1, p. 61-69 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immunogenicity of mycobacterial vesicles in humans: Identification of a new tuberculosis antibody biomarker

Ziegenbalg, A., Prados-Rosales, R., Jenny-Avital, E. R., Kim, R. S., Casadevall, A. & Achkar, J. M., Jul 1 2013, In : Tuberculosis. 93, 4, p. 448-455 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253

Swindells, S., Komarow, L., Tripathy, S., Cain, K. P., MacGregor, R. R., Achkar, J. M., Gupta, A., Veloso, V. G., Asmelash, A., Omoz-Oarhe, A. E., Gengiah, S., Lalloo, U., Allen, R., Shiboski, C., Andersen, J., Qasba, S. S. & Katzenstein, D. K., Apr 1 2013, In : International Journal of Tuberculosis and Lung Disease. 17, 4, p. 532-539 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
2012

Comparative evaluation of profiles of antibodies to mycobacterial capsular polysaccharides in tuberculosis patients and controls stratified by HIV status

Yu, X., Prados-Rosales, R., Jenny-Avital, E. R., Sosa, K., Casadevall, A. & Achkar, J. M., Feb 1 2012, In : Clinical and Vaccine Immunology. 19, 2, p. 198-208 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Independent association of younger age with hemoptysis in adults with pulmonary tuberculosis

Achkar, J. M. & Joseph, G., Jul 1 2012, In : International Journal of Tuberculosis and Lung Disease. 16, 7, p. 897-902 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2011

Adjunctive tests for diagnosis of tuberculosis: Serology, ELISPOT for site-specific lymphocytes, urinary lipoarabinomannan, string test, and fine needle aspiration

Achkar, J. M., Lawn, S. D., Moosa, M. Y. S., Wright, C. A. & Kasprowicz, V. O., Nov 15 2011, In : Journal of Infectious Diseases. 204, SUPPL. 4, p. S1130-S1141

Research output: Contribution to journalArticle

42 Scopus citations

Correlation between serum and plasma antibody titers to mycobacterial antigens

Siev, M., Yu, X., Prados-Rosales, R., Martiniuk, F. T., Casadevall, A. & Achkar, J. M., Jan 1 2011, In : Clinical and Vaccine Immunology. 18, 1, p. 173-175 3 p.

Research output: Contribution to journalArticle

19 Scopus citations

Incipient and subclinical tuberculosis: Defining early disease states in the context of host immune response

Achkar, J. M. & Jenny-Avital, E. R., Nov 15 2011, In : Journal of Infectious Diseases. 204, SUPPL. 4, p. S1179-S1186

Research output: Contribution to journalArticle

47 Scopus citations
2010

Antibodies against immunodominant antigens of Mycobacterium tuberculosis in subjects with suspected tuberculosis in the United States compared by HIV status

Achkar, J. M., Jenny-Avital, E., Yu, X., Burger, S., Leibert, E., Bilder, P. W., Almo, S. C., Casadevall, A. & Laal, S., Mar 1 2010, In : Clinical and Vaccine Immunology. 17, 3, p. 384-392 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
2008

Differences in clinical presentation among persons with pulmonary tuberculosis: A comparison of documented and undocumented foreign-born versus US-born persons

Achkar, J. M., Sherpa, T., Cohen, H. W. & Holzman, R. S., Nov 15 2008, In : Clinical Infectious Diseases. 47, 10, p. 1277-1283 7 p.

Research output: Contribution to journalArticle

38 Scopus citations
2006

Genetic analysis of HIV-1 strains in rural eastern Cameroon indicates the evolution of second-generation recombinants to circulating recombinant forms

Konings, F. A. J., Haman, G. R., Xue, Y., Urbanski, M. M., Hertzmark, K., Nanfack, A., Achkar, J. M., Burda, S. T. & Nyambi, P. N., Jul 1 2006, In : Journal of Acquired Immune Deficiency Syndromes. 42, 3, p. 331-341 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Mycobacterium tuberculosis Malate Synthase- And MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis

Achkar, J. M., Dong, Y., Holzman, R. S., Belisle, J., Kourbeti, I. S., Sherpa, T., Condos, R., Rom, W. N. & Laal, S., Nov 1 2006, In : Clinical and Vaccine Immunology. 13, 11, p. 1291-1293 3 p.

Research output: Contribution to journalArticle

30 Scopus citations
2005

Neutralizing antibody patterns and viral escape in HIV-1 non-B subtype chronically infected treatment-naive individuals

Kelly, H. R., Urbanski, M., Burda, S., Zhong, P., Konings, F., Nanfack, J., Tongo, M., Kinge, T., Achkar, J. & Nyambi, P., Dec 1 2005, In : Human Antibodies. 14, 3-4, p. 89-99 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2004

Infection with HIV type 1 group M non-B subtypes in individuals living in New York City

Achkar, J. M., Burda, S. T., Konings, F. A. J., Urbanski, M. M., Williams, C. A. U., Seifen, D., Kahirimbanyi, M. N., Vogler, M., Parta, M., Lupatkin, H. C., Zolla-Pazner, S. & Nyambi, P. N., Jul 1 2004, In : Journal of Acquired Immune Deficiency Syndromes. 36, 3, p. 835-844 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Protease Mutations in HIV-1 Non-B Strains Infecting Drug-Naive Villagers of Cameroon

Konings, F. A. J., Zhong, P., Agwara, M., Agyingi, L., Zekeng, L., Achkar, J. M., Ewane, L., Saa, Ze, E. A., Kinge, T. & Nyambi, P. N., Jan 1 2004, In : AIDS Research and Human Retroviruses. 20, 1, p. 105-109 5 p.

Research output: Contribution to journalArticle

34 Scopus citations
2003

Combined use of serum and urinary antibody for diagnosis of tuberculosis

Singh, K. K., Dong, Y., Hinds, L., Keen, M. A., Belisle, J. T., Zolla-Pazner, S., Achkar, J. M., Nadas, A. J., Arora, V. K. & Laal, S., Aug 1 2003, In : Journal of Infectious Diseases. 188, 3, p. 371-377 7 p.

Research output: Contribution to journalArticle

25 Scopus citations
2002

Ramsay hunt syndrome: An unusual variant after dental infection: Case report and literature review

Achkar, J. M., Wieczorek, R. & Zolla-Pazner, S., Nov 1 2002, In : Infectious Diseases in Clinical Practice. 11, 8, p. 456-458 3 p.

Research output: Contribution to journalArticle

2000

Polymerase chain reaction-based assay for antibody-mediated neutralization of HIV-1 reveals a population of nonneutralized virus undetected by conventional p24 assay

Achkar, J. M., Wang, X. H., Nyambi, P., Gorny, M. K., Zolla-Pazner, S. & Bandrés, J. C., Jul 1 2000, In : Journal of Acquired Immune Deficiency Syndromes. 24, 3, p. 203-210 8 p.

Research output: Contribution to journalArticle

7 Scopus citations