• 372 Citations
  • 12 h-Index
20092019
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Fingerprint Dive into the research topics where Ian T. Cook is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Sulfotransferases Medicine & Life Sciences
Phosphoadenosine Phosphosulfate Medicine & Life Sciences
Allosteric Site Medicine & Life Sciences
Nucleotides Medicine & Life Sciences
Dehydroepiandrosterone Medicine & Life Sciences
Sulfonation Chemical Compounds
Catalytic Domain Medicine & Life Sciences
Enzymes Medicine & Life Sciences

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Publications 2009 2019

  • 372 Citations
  • 12 h-Index
  • 22 Article

Allosteres to regulate neurotransmitter sulfonation

Darrah, K., Wang, T., Cook, I. T., Cacace, M., Deiters, A. & Leyh, T. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 7, p. 2293-2301 9 p.

Research output: Contribution to journalArticle

Sulfotransferases
Sulfonation
Neurotransmitter Agents
Free energy
Allosteric Site

Isoform-specific therapeutic control of sulfonation in humans

Cook, I. T., Wang, T. & Leyh, T. S., Jan 1 2019, In : Biochemical Pharmacology. 159, p. 25-31 7 p.

Research output: Contribution to journalArticle

Sulfonation
Acetaminophen
Sulfotransferases
Mefenamic Acid
Protein Isoforms
4 Citations (Scopus)
Neurotransmitter Agents
Sulfotransferases
Catechin
Allosteric Site
Binding Sites
2 Citations (Scopus)

The NSAID allosteric site of human cytosolic sulfotransferases

Wang, T., Cook, I. T. & Leyh, T. S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 49, p. 20305-20312 8 p.

Research output: Contribution to journalArticle

Allosteric Site
Sulfotransferases
Anti-Inflammatory Agents
Pharmaceutical Preparations
Mefenamic Acid
5 Citations (Scopus)

Controlling Sulfuryl-Transfer Biology

Cook, I. T., Wang, T., Wang, W., Kopp, F., Wu, P. & Leyh, T. S., May 19 2016, In : Cell Chemical Biology. 23, 5, p. 579-586 8 p.

Research output: Contribution to journalArticle

Sulfotransferases
Sulfonation
Estrogen Receptors
Phosphoadenosine Phosphosulfate
Selective Estrogen Receptor Modulators