• 6584 Citations
  • 39 h-Index
1981 …2019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Herbert M. Lachman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Schizophrenia Medicine & Life Sciences
Catechol O-Methyltransferase Medicine & Life Sciences
Bipolar Disorder Medicine & Life Sciences
Genes Medicine & Life Sciences
Alleles Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Genotype Medicine & Life Sciences
Psychiatry Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 1985 2019

Induced Pluripotent Stem Cells
Neurons
Alleles
Genes
Schizophrenia
Long Noncoding RNA
Schizophrenia
Neurons
RNA
Induced Pluripotent Stem Cells
Induced Pluripotent Stem Cells
MicroRNAs
Schizophrenia
Neurons
Knockout Mice
Induced Pluripotent Stem Cells
Schizophrenia
Neurons
High-Throughput Nucleotide Sequencing
Pyramidal Cells
Schizophrenia
Alleles
Genes
Genome-Wide Association Study
DNA

Publications 1981 2018

  • 6584 Citations
  • 39 h-Index
  • 105 Article
  • 1 Comment/debate
9 Citations (Scopus)

Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons

Wang, P., Zhao, D., Lachman, H. M. & Zheng, D., Dec 1 2018, In : Translational Psychiatry. 8, 1, 58.

Research output: Contribution to journalArticle

Gene Expression
Neurons
Gene Regulatory Networks
Autism Spectrum Disorder
Single-Cell Analysis
3 Citations (Scopus)

Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: Defective F-actin polymerization and WAVE-1 expression in neuronal cells

Barnes, J., Salas, F., Mokhtari, R., Dolstra, H., Pedrosa, E. & Lachman, H. M., Aug 15 2018, In : Molecular Autism. 9, 1, 44.

Research output: Contribution to journalArticle

Oculocerebrorenal Syndrome
Induced Pluripotent Stem Cells
Polymerization
Actins
Developmental Disabilities
2 Citations (Scopus)

Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

Zhao, D., Lin, M., Pedrosa, E., Lachman, H. M. & Zheng, D., Nov 10 2017, In : BMC Genomics. 18, 1, 860.

Research output: Contribution to journalArticle

RNA
Gene Expression
Brain
Genes
Psychiatry
42 Citations (Scopus)

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

Wang, P., Mokhtari, R., Pedrosa, E., Kirschenbaum, M., Bayrak, C., Zheng, D. & Lachman, H. M., Mar 20 2017, In : Molecular Autism. 8, 1, 11.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Organoids
Induced Pluripotent Stem Cells
Gene Knockout Techniques
Gene Regulatory Networks
11 Citations (Scopus)
Rett Syndrome
Macrophage Activation
Microglia
Gene Expression Profiling
Gene Expression