Projects per year
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- 3 Similar Profiles
Schizophrenia
Medicine & Life Sciences
Catechol O-Methyltransferase
Medicine & Life Sciences
Bipolar Disorder
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Alleles
Medicine & Life Sciences
Induced Pluripotent Stem Cells
Medicine & Life Sciences
Genotype
Medicine & Life Sciences
Psychiatry
Medicine & Life Sciences
Network
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Grants 1985 2019
- 8 Finished
Monoallelic expression in neurons derived from induced pluripotent stem cells
8/15/13 → 5/31/19
Project: Research project
Induced Pluripotent Stem Cells
Neurons
Alleles
Genes
Schizophrenia
Schizophrenia-associated long non-coding RNAs in neurons derived from iPS cells
8/1/13 → 7/31/15
Project: Research project
Long Noncoding RNA
Schizophrenia
Neurons
RNA
Induced Pluripotent Stem Cells
microRNA analysis of neurons generated from patient-specific iPSCs
7/1/12 → 6/30/14
Project: Research project
Induced Pluripotent Stem Cells
MicroRNAs
Schizophrenia
Neurons
Knockout Mice
Analysis of Glutamatergic Neurons Derived from Patient-Specific iPS Cells
Lachman, H. M. & Lachman, H.
9/30/09 → 8/31/14
Project: Research project
Induced Pluripotent Stem Cells
Schizophrenia
Neurons
High-Throughput Nucleotide Sequencing
Pyramidal Cells
Schizophrenia
Alleles
Genes
Genome-Wide Association Study
DNA
Publications 1981 2018
8
Citations
(Scopus)
Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons
Wang, P., Zhao, D., Lachman, H. M. & Zheng, D., Dec 1 2018, In : Translational Psychiatry. 8, 1, 58.Research output: Contribution to journal › Article
Gene Expression
Neurons
Gene Regulatory Networks
Autism Spectrum Disorder
Single-Cell Analysis
2
Citations
(Scopus)
Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: Defective F-actin polymerization and WAVE-1 expression in neuronal cells
Barnes, J., Salas, F., Mokhtari, R., Dolstra, H., Pedrosa, E. & Lachman, H. M., Aug 15 2018, In : Molecular Autism. 9, 1, 44.Research output: Contribution to journal › Article
Oculocerebrorenal Syndrome
Induced Pluripotent Stem Cells
Polymerization
Actins
Developmental Disabilities
2
Citations
(Scopus)
Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis
Zhao, D., Lin, M., Pedrosa, E., Lachman, H. M. & Zheng, D., Nov 10 2017, In : BMC Genomics. 18, 1, 860.Research output: Contribution to journal › Article
RNA
Gene Expression
Brain
Genes
Psychiatry
36
Citations
(Scopus)
CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells
Wang, P., Mokhtari, R., Pedrosa, E., Kirschenbaum, M., Bayrak, C., Zheng, D. & Lachman, H. M., Mar 20 2017, In : Molecular Autism. 8, 1, 11.Research output: Contribution to journal › Article
Clustered Regularly Interspaced Short Palindromic Repeats
Organoids
Induced Pluripotent Stem Cells
Gene Knockout Techniques
Gene Regulatory Networks
7
Citations
(Scopus)
Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress
Zhao, D., Mokhtari, R., Pedrosa, E., Birnbaum, R., Zheng, D. & Lachman, H. M., Mar 29 2017, In : Molecular Autism. 8, 1, 17.Research output: Contribution to journal › Article
Rett Syndrome
Macrophage Activation
Microglia
Gene Expression Profiling
Gene Expression