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Herbert M. Lachman, M.D.

  • 6691 Citations
  • 39 h-Index
1981 …2019

Research output per year

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Grants

Monoallelic expression in neurons derived from induced pluripotent stem cells

Lachman, H. M.

National Institutes of Health

8/15/13 → 5/31/19

Project: Research project

    • Schizophrenia-associated long non-coding RNAs in neurons derived from iPS cells

    Lachman, H. M.

    National Institutes of Health

    8/1/13 → 7/31/15

    Project: Research project

    • microRNA analysis of neurons generated from patient-specific iPSCs

    Lachman, H. M.

    National Institutes of Health

    7/1/12 → 6/30/14

    Project: Research project

    • Analysis of Glutamatergic Neurons Derived from Patient-Specific iPS Cells

    Lachman, H. M. & Lachman, H.

    National Institutes of Health

    9/30/09 → 8/31/14

    Project: Research project

    • Analysis of bipolar and schizophrenia candidate alleles

    Lachman, H. M.

    National Institutes of Health

    12/1/04 → 5/31/14

    Project: Research project

    • Publications

    Mitochondrial deficits in human iPSC-derived neurons from patients with 22q11.2 deletion syndrome and schizophrenia

    Li, J., Ryan, S. K., Deboer, E., Cook, K., Fitzgerald, S., Lachman, H. M., Wallace, D. C., Goldberg, E. M. & Anderson, S. A., Dec 1 2019, In : Translational psychiatry. 9, 1, 302.

    Research output: Contribution to journal › Article

    Open Access

    • Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons

    Wang, P., Zhao, D., Lachman, H. M. & Zheng, D., Dec 1 2018, In : Translational psychiatry. 8, 1, 58.

    Research output: Contribution to journal › Article

    • 11 Scopus citations

    Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: Defective F-actin polymerization and WAVE-1 expression in neuronal cells

    Barnes, J., Salas, F., Mokhtari, R., Dolstra, H., Pedrosa, E. & Lachman, H. M., Aug 15 2018, In : Molecular Autism. 9, 1, 44.

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

    Zhao, D., Lin, M., Pedrosa, E., Lachman, H. M. & Zheng, D., Nov 10 2017, In : BMC Genomics. 18, 1, 860.

    Research output: Contribution to journal › Article

    • 4 Scopus citations

    CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

    Wang, P., Mokhtari, R., Pedrosa, E., Kirschenbaum, M., Bayrak, C., Zheng, D. & Lachman, H. M., Mar 20 2017, In : Molecular Autism. 8, 1, 11.

    Research output: Contribution to journal › Article

    • 51 Scopus citations